7TNY
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![BU of 7tny by Molmil](/molmil-images/mine/7tny) | Cryo-EM structure of RIG-I in complex with p2dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TO0
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![BU of 7to0 by Molmil](/molmil-images/mine/7to0) | Cryo-EM structure of RIG-I in complex with OHdsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, OHdsRNA, ZINC ION | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TNZ
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![BU of 7tnz by Molmil](/molmil-images/mine/7tnz) | Cryo-EM structure of RIG-I in complex with p1dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p1dsRNA | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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4PEI
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![BU of 4pei by Molmil](/molmil-images/mine/4pei) | Dbr1 in complex with synthetic branched RNA analog | Descriptor: | GLYCEROL, NICKEL (II) ION, RNA (5'-R(*(G46)P*U)-3'), ... | Authors: | Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res., 42, 2014
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6RH3
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![BU of 6rh3 by Molmil](/molmil-images/mine/6rh3) | Cryo-EM structure of E. coli RNA polymerase elongation complex bound to CTP substrate | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | Deposit date: | 2019-04-18 | Release date: | 2019-07-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation. Mol.Cell, 75, 2019
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3O3G
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![BU of 3o3g by Molmil](/molmil-images/mine/3o3g) | T. maritima RNase H2 in complex with nucleic acid substrate and calcium ions | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), ... | Authors: | Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M. | Deposit date: | 2010-07-24 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage. Mol.Cell, 40, 2010
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7KQM
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![BU of 7kqm by Molmil](/molmil-images/mine/7kqm) | Binary complex of TERT (telomerase reverse transcriptase) with RNA/telomeric DNA hybrid | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*GP*CP*AP*CP*CP*TP*G)-3'), ... | Authors: | Choi, W.S, Weng, P.J, Yang, W. | Deposit date: | 2020-11-17 | Release date: | 2022-03-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Flexibility of telomerase in binding the RNA template and DNA telomeric repeat. Proc.Natl.Acad.Sci.USA, 119, 2022
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6GD1
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![BU of 6gd1 by Molmil](/molmil-images/mine/6gd1) | Structure of HuR RRM3 | Descriptor: | SODIUM ION, Thioredoxin 1,ELAV-like protein 1 | Authors: | Pabis, M, Sattler, M. | Deposit date: | 2018-04-21 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs. Nucleic Acids Res., 47, 2019
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6O0Y
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![BU of 6o0y by Molmil](/molmil-images/mine/6o0y) | Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium | Descriptor: | 3' product of target strand DNA, 5' product of target strand DNA, CRISPR-associated endonuclease Cas9/Csn1, ... | Authors: | Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S. | Deposit date: | 2019-02-17 | Release date: | 2019-07-10 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9. Nat.Struct.Mol.Biol., 26, 2019
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4ZLR
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![BU of 4zlr by Molmil](/molmil-images/mine/4zlr) | Structure of the Brat-NHL domain bound to consensus RNA motif | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Brain tumor protein, PENTAETHYLENE GLYCOL, ... | Authors: | Jakob, L, Treiber, N, Treiber, T, Stotz, M, Loedige, I, Meister, G. | Deposit date: | 2015-05-01 | Release date: | 2015-11-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation. Cell Rep, 13, 2015
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7MKI
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![BU of 7mki by Molmil](/molmil-images/mine/7mki) | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR (-5G to C) promoter DNA | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Saecker, R.M, Darst, S.A, Chen, J. | Deposit date: | 2021-04-23 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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5HSW
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![BU of 5hsw by Molmil](/molmil-images/mine/5hsw) | KSHV SOX RNA complex | Descriptor: | ACETATE ION, ORF 37, RNA (5'-R(P*UP*CP*UP*UP*GP*AP*AP*GP*CP*AP*GP*CP*UP*UP*CP*CP*AP*G)-3') | Authors: | Barrett, T.E. | Deposit date: | 2016-01-26 | Release date: | 2017-02-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing. Nucleic Acids Res., 45, 2017
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6O6V
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![BU of 6o6v by Molmil](/molmil-images/mine/6o6v) | |
1OOA
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![BU of 1ooa by Molmil](/molmil-images/mine/1ooa) | CRYSTAL STRUCTURE OF NF-kB(p50)2 COMPLEXED TO A HIGH-AFFINITY RNA APTAMER | Descriptor: | Nuclear factor NF-kappa-B p105 subunit, RNA aptamer | Authors: | Huang, D.B, Vu, D, Cassiday, L.A, Zimmerman, J.M, Maher III, L.J, Ghosh, G. | Deposit date: | 2003-03-03 | Release date: | 2003-07-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer. Proc.Natl.Acad.Sci.USA, 100, 2003
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6I2N
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![BU of 6i2n by Molmil](/molmil-images/mine/6i2n) | Helical RNA-bound Hantaan virus nucleocapsid | Descriptor: | Nucleoprotein, RNA (5'-R(P*UP*UP*U)-3') | Authors: | Arragain, B, Reguera, J, Desfosses, A, Gutsche, I, Schoehn, G, Malet, H. | Deposit date: | 2018-11-01 | Release date: | 2019-01-23 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms. Elife, 8, 2019
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1P16
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![BU of 1p16 by Molmil](/molmil-images/mine/1p16) | Structure of an mRNA capping enzyme bound to the phosphorylated carboxyl-terminal domain of RNA polymerase II | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, ... | Authors: | Fabrega, C, Shen, V, Shuman, S, Lima, C.D. | Deposit date: | 2003-04-11 | Release date: | 2003-07-15 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II. Mol.Cell, 11, 2003
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6O6X
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![BU of 6o6x by Molmil](/molmil-images/mine/6o6x) | |
6UV0
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![BU of 6uv0 by Molmil](/molmil-images/mine/6uv0) | |
6OZJ
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![BU of 6ozj by Molmil](/molmil-images/mine/6ozj) | |
6OZQ
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![BU of 6ozq by Molmil](/molmil-images/mine/6ozq) | |
6OZL
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![BU of 6ozl by Molmil](/molmil-images/mine/6ozl) | |
6OZK
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![BU of 6ozk by Molmil](/molmil-images/mine/6ozk) | |
6OZR
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![BU of 6ozr by Molmil](/molmil-images/mine/6ozr) | |
7UM0
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![BU of 7um0 by Molmil](/molmil-images/mine/7um0) | Structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with two DNA oligonucleotides containing the AR9 P077 promoter as determined by cryo-EM | Descriptor: | DNA (5'-D(P*GP*UP*U)-3'), DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, ... | Authors: | Leiman, P.G, Fraser, A, Sokolova, M.L. | Deposit date: | 2022-04-05 | Release date: | 2022-07-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
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7UM1
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![BU of 7um1 by Molmil](/molmil-images/mine/7um1) | Structure of bacteriophage AR9 non-virion RNAP polymerase holoenzyme determined by cryo-EM | Descriptor: | DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... | Authors: | Leiman, P.G, Fraser, A, Sokolova, M.L. | Deposit date: | 2022-04-05 | Release date: | 2022-07-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
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