PDB: 45522 resultsInfo pagesStatus searchChemie searchBIRD

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3SX9	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-132 Descriptor: 3-(6-ethoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 Authors: Larson, E.T, Merritt, E.A. Deposit date: 2011-07-14 Release date: 2012-03-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1. J.Med.Chem., 55, 2012
2WFB	High resolution structure of the apo form of the orange protein (ORP) from Desulfovibrio gigas Descriptor: ACETATE ION, PHOSPHATE ION, PUTATIVE UNCHARACTERIZED PROTEIN ORP Authors: Najmudin, S, Bonifacio, C, Duarte, A.G, Pereira, A.S, Moura, I, Moura, J.M, Romao, M.J. Deposit date: 2009-04-03 Release date: 2010-05-26 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: High Resolution Crystal Structure of the Apo Form of the Orange Protein (Apo-Orp) from Desulfovibrio Gigas To be Published
3T0L	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening Descriptor: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... Authors: Thiel, P, Ottmann, C. Deposit date: 2011-07-20 Release date: 2012-12-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
3T0S	Crystal structure of Pseudomonas aeruginosa OccK4 (OpdL) Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, porin Authors: van den Berg, B, Eren, E. Deposit date: 2011-07-20 Release date: 2012-02-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Substrate Specificity within a Family of Outer Membrane Carboxylate Channels. Plos Biol., 10, 2012
3T15	Structure of green-type Rubisco activase from tobacco Descriptor: Ribulose bisphosphate carboxylase/oxygenase activase 1, chloroplastic Authors: Stotz, M, Wendler, P, Mueller-Cajar, O, Hartl, F.U, Bracher, A, Hayer-Hartl, M. Deposit date: 2011-07-21 Release date: 2011-11-09 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structure of green-type Rubisco activase from tobacco. Nat.Struct.Mol.Biol., 18, 2011
3T5X	PCID2:DSS1 Structure Descriptor: 26S proteasome complex subunit DSS1, PCI domain-containing protein 2 Authors: Stewart, M, Ellisdon, A.M. Deposit date: 2011-07-28 Release date: 2012-02-22 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.123 Å) Cite: Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex. Nat.Struct.Mol.Biol., 19, 2012
3SQZ	Crystal structure of HMG_CoA synthase complexed with CoA Descriptor: COENZYME A, GLYCEROL, Putative hydroxymethylglutaryl-CoA synthase Authors: Liu, Y.H, Fu, T.M, Liu, X, Su, X.D. Deposit date: 2011-07-06 Release date: 2012-07-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Crystal structure of HMG-CoA synthase from Streptococcus mutans To be Published
3D65	Crystal structure of Textilinin-1, a Kunitz-type serine protease inhibitor from the Australian Common Brown snake venom, in complex with trypsin Descriptor: CALCIUM ION, Cationic trypsin, Textilinin Authors: Millers, E.-K.I, Masci, P.P, Lavin, M.F, de Jersey, J, Guddat, L.W. Deposit date: 2008-05-19 Release date: 2009-06-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Crystal structure of Textilinin-1, a Kunitz-type serine protease inhibitor from the Australian Common Brown snake venom, in complex with trypsin To be Published
3CYE	Cyrstal structure of the native 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... Authors: Zhu, X, Xu, X, Wilson, I.A. Deposit date: 2008-04-25 Release date: 2008-08-05 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure determination of the 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects Acta Crystallogr.,Sect.D, 64, 2008
2W4S	novel RNA-binding domain in Cryptosporidium parvum at 2.5 angstrom resolution Descriptor: Ankyrin-repeat protein Authors: Varrot, A, Mackereth, C, Mourao, A, Sattler, M, Cusack, S. Deposit date: 2008-12-02 Release date: 2009-12-29 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax. RNA, 16, 2010
3CEK	Crystal structure of human dual specificity protein kinase (TTK) Descriptor: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Dual specificity protein kinase TTK Authors: Filippakopoulos, P, Soundararajan, M, Keates, T, Elkins, J.M, King, O, Fedorov, O, Picaud, S.S, Pike, A.C.W, Roos, A, Pilka, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2008-02-29 Release date: 2008-03-18 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat.Chem.Biol., 6, 2010
3CFO	Triple Mutant APO structure Descriptor: DNA polymerase, GUANOSINE, SULFATE ION Authors: Wang, J, Klimenko, D, Wang, M, Steitz, T.A, Konigsberg, W.H. Deposit date: 2008-03-04 Release date: 2009-03-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Insights into base selectivity from the structures of an RB69 DNA Polymerase triple mutant To be Published
2VW8	Crystal Structure of Quinolone signal response protein pqsE from Pseudomonas aeruginosa Descriptor: 1,2-ETHANEDIOL, CACODYLATE ION, FE (II) ION, ... Authors: Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Oke, M, Naismith, J.H, White, M.F. Deposit date: 2008-06-17 Release date: 2010-07-14 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The Scottish Structural Proteomics Facility: Targets, Methods and Outputs. J.Struct.Funct.Genomics, 11, 2010
3D3X	Crystal structure of botulinum neurotoxin serotype E catalytic domain in complex with SNAP-25 substrate peptide Descriptor: SNAP-25 substrate peptide, SULFATE ION, Type E botulinum toxin, ... Authors: Agarwal, R, Swaminathan, S. Deposit date: 2008-05-13 Release date: 2008-07-08 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.25 Å) Cite: SNAP-25 substrate peptide (residues 180-183) binds to but bypasses cleavage by catalytically active Clostridium botulinum neurotoxin E. J.Biol.Chem., 283, 2008
2VQ1	anti trimeric Lewis X Fab54-5C10-A Descriptor: ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION, AZIDE ION, GLYCEROL, ... Authors: de Geus, D.C, van Roon, A.M.M, Thomassen, E.A.J, Hokke, C.H, Deelder, A.M, Abrahams, J.P. Deposit date: 2008-03-10 Release date: 2009-01-27 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Characterization of a Diagnostic Fab Fragment Binding Trimeric Lewis X. Proteins, 76, 2009
3CNW	Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196. Descriptor: Protein XoxI Authors: Kuzin, A.P, Abashidze, M, Seetharaman, J, Wang, H, Ciccosanti, C, Mao, L, Xiao, R, Nair, R, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) Deposit date: 2008-03-26 Release date: 2008-04-08 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196. To Be Published
2WD7	PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH NADP AND DDD00066750 Descriptor: 6-chloro-1H-benzimidazol-2-amine, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE Authors: Robinson, D.A, Wyatt, P.G, Spinks, D, Brenk, R. Deposit date: 2009-03-20 Release date: 2009-06-30 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening. J.Med.Chem., 52, 2009
3POT	Structural analysis of a Ni(III)-methyl species in methyl-coenzyme M reductase from Methanothermobacter marburgensis Descriptor: 1,2-ETHANEDIOL, 1-THIOETHANESULFONIC ACID, Coenzyme B, ... Authors: Cedervall, P.E, Wilmot, C.M. Deposit date: 2010-11-23 Release date: 2011-04-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Structural Analysis of a Ni-Methyl Species in Methyl-Coenzyme M Reductase from Methanothermobacter marburgensis. J.Am.Chem.Soc., 133, 2011
3PQD	Crystal structure of L-lactate dehydrogenase from Bacillus subtilis complexed with FBP and NAD+ Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Zhang, Y, Garavito, R.M. Deposit date: 2010-11-26 Release date: 2012-01-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.376 Å) Cite: Crystal structure of L-lactate dehydrogenase from Bacillus subtilis complexed with FBP and NAD+ To be Published
3CSG	Crystal Structure of Monobody YS1(MBP-74)/Maltose Binding Protein Fusion Complex Descriptor: Maltose-binding protein Monobody YS1 Fusion Authors: Gilbreth, R.N, Koide, S. Deposit date: 2008-04-09 Release date: 2008-07-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.798 Å) Cite: A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-Protein Interfaces J.Mol.Biol., 381, 2008
3PWQ	The Phenylacetyl-CoA monooxygenase PaaAC subcomplex Descriptor: Phenylacetic acid degradation protein paaA, Phenylacetic acid degradation protein paaC Authors: Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2010-12-08 Release date: 2011-01-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex. J.Biol.Chem., 286, 2011
2VYN	Structure of E.Coli GAPDH Rat Sperm GAPDH heterotetramer Descriptor: FORMIC ACID, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Frayne, J, Taylor, A, Hall, L, Hadfield, A. Deposit date: 2008-07-25 Release date: 2008-08-05 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of Insoluble Rat Sperm Glyceraldehyde-3-Phosphate Dehydrogenase (Gapdh) Via Heterotetramer Formation with Escherichia Coli Gapdh Reveals Target for Contraceptive Design. J.Biol.Chem., 284, 2009
3RF4	Ancylostoma ceylanicum mif in complex with furosemide Descriptor: 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, ACETATE ION, IMIDAZOLE, ... Authors: Cho, Y, Lolis, E. Deposit date: 2011-04-05 Release date: 2011-10-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors. Chem.Biol., 18, 2011
3QZV	Crystal Structure of BPTF PHD-linker-bromo in complex with histone H4K12ac peptide Descriptor: Histone H4, Nucleosome-remodeling factor subunit BPTF, ZINC ION Authors: Li, H, Ruthenburg, A.J, Patel, D.J. Deposit date: 2011-03-07 Release date: 2011-06-01 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.999 Å) Cite: Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions. Cell(Cambridge,Mass.), 145, 2011
2VYV	Structure of E.Coli GAPDH Rat Sperm GAPDH heterotetramer Descriptor: FORMIC ACID, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Frayne, J, Taylor, A, Hall, L, Hadfield, A. Deposit date: 2008-07-29 Release date: 2008-08-05 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Structure of Insoluble Rat Sperm Glyceraldehyde-3-Phosphate Dehydrogenase (Gapdh) Via Heterotetramer Formation with Escherichia Coli Gapdh Reveals Target for Contraceptive Design. J.Biol.Chem., 284, 2009

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