1ZVW
| The Crystal Structure of TrpD (Rv2192c) from Mycobacterium tuberculosis in Complex with PRPP and Magnesium | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, BENZAMIDINE, ... | Authors: | Lee, C.E, Lott, J.S, Baker, E.N, Arcus, V.L, Javid-Majd, F, Goodfellow, C, Hung, L.-W, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-06-02 | Release date: | 2006-01-17 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Crystal Structure of TrpD, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate. J.Mol.Biol., 355, 2006
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7YKR
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2BPQ
| Anthranilate phosphoribosyltransferase (TrpD) from Mycobacterium tuberculosis (Apo structure) | Descriptor: | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE, BENZAMIDINE, GLYCEROL | Authors: | Lee, C.E, Goodfellow, C, Javid-Majd, F, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-04-22 | Release date: | 2006-01-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Crystal Structure of Trpd, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium Tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate J.Mol.Biol., 355, 2006
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8SR9
| Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium | Descriptor: | CHOLESTEROL, MAGNESIUM ION, TRPM2 chanzyme | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
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8SR8
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8SRA
| Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium | Descriptor: | CALCIUM ION, CHOLESTEROL, TRPM2 chanzyme | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
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8SRC
| Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
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8SR7
| Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate | Descriptor: | 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (1.97 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
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8SRB
| Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA and ADP-ribose | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, TRPM2 chanzyme | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
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2I1D
| DPC micelle-bound NMR structures of Tritrp1 | Descriptor: | 13-mer from Prophenin-1 containing WWW | Authors: | Schibli, D.J, Nguyen, L.T. | Deposit date: | 2006-08-14 | Release date: | 2006-11-28 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of tritrpticin analogs: potential relationships between antimicrobial activities, model membrane interactions, and their micelle-bound NMR structures Biophys.J., 91, 2006
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2I1F
| DPC micelle-bound NMR structures of Tritrp3 | Descriptor: | 13-mer analogue of Prophenin-1 containing WWW | Authors: | Schibli, D.J, Nguyen, L.T. | Deposit date: | 2006-08-14 | Release date: | 2006-11-28 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of tritrpticin analogs: potential relationships between antimicrobial activities, model membrane interactions, and their micelle-bound NMR structures Biophys.J., 91, 2006
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2I1G
| DPC micelle-bound NMR structures of Tritrp5 | Descriptor: | 13-mer analogue of Prophenin-1 containing WWW | Authors: | Schibli, D.J, Nguyen, L.T. | Deposit date: | 2006-08-14 | Release date: | 2006-11-28 | Last modified: | 2020-06-24 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of tritrpticin analogs: potential relationships between antimicrobial activities, model membrane interactions, and their micelle-bound NMR structures Biophys.J., 91, 2006
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2I1I
| DPC micelle-bound NMR structures of Tritrp8 | Descriptor: | 13-mer analogue of Prophenin-1 containing WWW | Authors: | Schibli, D.J, Nguyen, L.T. | Deposit date: | 2006-08-14 | Release date: | 2006-11-28 | Last modified: | 2020-06-24 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of tritrpticin analogs: potential relationships between antimicrobial activities, model membrane interactions, and their micelle-bound NMR structures Biophys.J., 91, 2006
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2I1E
| DPC micelle-bound NMR structures of Tritrp2 | Descriptor: | 13-mer analogue of Prophenin-1 containing WWW | Authors: | Schibli, D.J, Nguyen, L.T. | Deposit date: | 2006-08-14 | Release date: | 2006-11-28 | Last modified: | 2020-06-24 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of tritrpticin analogs: potential relationships between antimicrobial activities, model membrane interactions, and their micelle-bound NMR structures Biophys.J., 91, 2006
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3UC8
| Trp-cage cyclo-TC1 - tetragonal crystal form | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, cyclo-TC1 | Authors: | Scian, M, Le Trong, I, Stenkamp, R.E, Andersen, N.H. | Deposit date: | 2011-10-26 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction. Proc.Natl.Acad.Sci.USA, 109, 2012
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3UC7
| Trp-cage cyclo-TC1 - monoclinic crystal form | Descriptor: | CHLORIDE ION, Cyclo-TC1 | Authors: | Scian, M, Le Trong, I, Stenkamp, R.E, Andersen, N.H. | Deposit date: | 2011-10-26 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction. Proc.Natl.Acad.Sci.USA, 109, 2012
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3SSW
| E. coli trp aporepressor | Descriptor: | Trp operon repressor | Authors: | Benoff, B, Carey, J, Berman, H.M, Lawson, C.L. | Deposit date: | 2011-07-08 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6693 Å) | Cite: | Environment-dependent long-range structural distortion in a temperature-sensitive point mutant. Protein Sci., 21, 2012
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6RMV
| The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer | Descriptor: | GLYCEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Gruss, F, Oberwinkler, J, Ulens, C. | Deposit date: | 2019-05-07 | Release date: | 2020-10-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The structural basis for an on-off switch controlling G beta gamma-mediated inhibition of TRPM3 channels. Proc.Natl.Acad.Sci.USA, 117, 2020
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2I1H
| DPC micelle-bound NMR structures of Tritrp7 | Descriptor: | 13-mer analogue of Prophenin-1 containing WWW | Authors: | Schibli, D.J, Nguyen, L.T. | Deposit date: | 2006-08-14 | Release date: | 2006-11-28 | Last modified: | 2020-06-24 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of tritrpticin analogs: potential relationships between antimicrobial activities, model membrane interactions, and their micelle-bound NMR structures Biophys.J., 91, 2006
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5YE1
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6AYG
| Human Apo-TRPML3 channel at pH 4.8 | Descriptor: | Mucolipin-3 | Authors: | Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J. | Deposit date: | 2017-09-08 | Release date: | 2017-11-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.65 Å) | Cite: | Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states. Nat. Struct. Mol. Biol., 24, 2017
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6AYE
| Human apo-TRPML3 channel at pH 7.4 | Descriptor: | Mucolipin-3 | Authors: | Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J. | Deposit date: | 2017-09-08 | Release date: | 2017-11-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.06 Å) | Cite: | Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states. Nat. Struct. Mol. Biol., 24, 2017
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4B27
| Trp RNA-binding attenuation protein: modifying symmetry and stability of a circular oligomer | Descriptor: | TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN | Authors: | Bayfield, O.W, Chen, C, Patterson, A.R, Luan, W, Smits, C, Gollnick, P, Antson, A.A. | Deposit date: | 2012-07-12 | Release date: | 2012-09-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Trp RNA-Binding Attenuation Protein: Modifying Symmetry and Stability of a Circular Oligomer. Plos One, 7, 2012
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7B1G
| TRPC4 in complex with Calmodulin | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CALCIUM ION, Calmodulin-1, ... | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | Deposit date: | 2020-11-24 | Release date: | 2020-12-09 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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7B16
| TRPC4 in complex with inhibitor GFB-9289 | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, 5-chloranyl-4-(4-cyclohexyl-3-oxidanylidene-piperazin-1-yl)-1~{H}-pyridazin-6-one, CALCIUM ION, ... | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | Deposit date: | 2020-11-23 | Release date: | 2020-12-09 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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