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2HC2
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BU of 2hc2 by Molmil
Engineered protein tyrosine phosphatase beta catalytic domain
Descriptor: MAGNESIUM ION, Receptor-type tyrosine-protein phosphatase beta, SODIUM ION
Authors:Evdokimov, A.G, Pokross, M, Walter, R, Mekel, M.
Deposit date:2006-06-15
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
Acta Crystallogr.,Sect.D, 62, 2006
2H04
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BU of 2h04 by Molmil
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Descriptor: Protein tyrosine phosphatase, receptor type, B,, ...
Authors:Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M, Gray, J.L, Peters, K.G, Maier, M.B, Amarasinghe, K.D, Clark, C.M, Nichols, R.
Deposit date:2006-05-13
Release date:2006-06-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
Bioorg.Med.Chem.Lett., 16, 2006
3NDZ
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BU of 3ndz by Molmil
The structure of the catalytic and carbohydrate binding domain of endoglucanase D from Clostridium cellulovorans bound to cellotriose
Descriptor: Endoglucanase D, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Bianchetti, C.M, Smith, R.W, Bingman, C.A, Phillips Jr, G.N.
Deposit date:2010-06-08
Release date:2011-06-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:The structure of the catalytic and carbohydrate binding domain of endoglucanase D bound to cellotriose
To be Published
2I4H
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BU of 2i4h by Molmil
Structural studies of protein tyrosine phosphatase beta catalytic domain co-crystallized with a sulfamic acid inhibitor
Descriptor: CHLORIDE ION, MAGNESIUM ION, N-(TERT-BUTOXYCARBONYL)-L-TYROSYL-N-METHYL-4-(SULFOAMINO)-L-PHENYLALANINAMIDE, ...
Authors:Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
Deposit date:2006-08-21
Release date:2006-08-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
Acta Crystallogr.,Sect.D, 62, 2006
3PJQ
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BU of 3pjq by Molmil
Trypanosoma cruzi trans-sialidase-like inactive isoform (including the natural mutation Tyr342His) in complex with lactose
Descriptor: Trans-sialidase, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
Authors:Oppezzo, P, Baraibar, M, Obal, G, Pritsch, O, Alzari, P.M, Buschiazzo, A.
Deposit date:2010-11-10
Release date:2011-06-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of an enzymatically inactive trans-sialidase-like lectin from Trypanosoma cruzi: the carbohydrate binding mechanism involves residual sialidase activity.
Biochim.Biophys.Acta, 1814, 2011
2PU3
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BU of 2pu3 by Molmil
Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida
Descriptor: CHLORIDE ION, Endonuclease I, MAGNESIUM ION
Authors:Altermark, B, Helland, R, Moe, E, Willassen, N.P, Smalas, A.O.
Deposit date:2007-05-08
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida.
Acta Crystallogr.,Sect.D, 64, 2008
5TND
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BU of 5tnd by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 1,2-Epoxycyclohexane hydrolysis intermediate
Descriptor: (1R,2R)-cyclohexane-1,2-diol, (1S,2S)-cyclohexane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNM
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BU of 5tnm by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (R)-1,2-Epoxyoctane hydrolysis intermediate
Descriptor: (2R)-octane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNE
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BU of 5tne by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted cis-Stilbene Oxide hydrolysis intermediate
Descriptor: (1R,2R)-1,2-diphenylethane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNP
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BU of 5tnp by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted Styrene oxide hydrolysis intermediate
Descriptor: (1R)-1-phenylethane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNI
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BU of 5tni by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted S-Styrene oxide hydrolysis intermediate
Descriptor: (1R)-1-phenylethane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
2NR9
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BU of 2nr9 by Molmil
Crystal structure of GlpG, Rhomboid Peptidase from Haemophilus influenzae
Descriptor: (R)-2-(FORMYLOXY)-3-(PHOSPHONOOXY)PROPYL PENTANOATE, 3,6,12,15,18,21,24-HEPTAOXAHEXATRIACONTAN-1-OL, Protein glpG homolog
Authors:Lemieux, M.J, Fischer, S.J, Cherney, M.M, Bateman, K.S, James, M.N.G.
Deposit date:2006-11-01
Release date:2006-11-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis.
Proc.Natl.Acad.Sci.USA, 104, 2007
2QA1
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BU of 2qa1 by Molmil
Crystal structure of PgaE, an aromatic hydroxylase involved in angucycline biosynthesis
Descriptor: 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Koskiniemi, H, Dobritzsch, D, Metsa-Ketela, M, Kallio, P, Niemi, J, Schneider, G.
Deposit date:2007-06-14
Release date:2007-08-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis
J.Mol.Biol., 372, 2007
2QB0
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BU of 2qb0 by Molmil
Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.
Descriptor: MANGANESE (II) ION, Transcription factor ETV6, Transcription factor ETV6,Endolysin
Authors:Nauli, S, Bowie, J.U.
Deposit date:2007-06-15
Release date:2008-10-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Polymer-driven crystallization.
Protein Sci., 16, 2007
2QA2
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BU of 2qa2 by Molmil
Crystal structure of CabE, an aromatic hydroxylase from angucycline biosynthesis, determined to 2.7 A resolution
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Polyketide oxygenase CabE
Authors:Koskiniemi, H, Dobritzsch, D, Metsa-Ketela, M, Kallio, P, Niemi, J, Schneider, G.
Deposit date:2007-06-14
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis
J.Mol.Biol., 372, 2007
2H03
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BU of 2h03 by Molmil
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Descriptor: (4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M, Gray, J.L, Peters, K.G, Maier, M.B, Amarasinghe, K.D, Clark, C.M, Nichols, R.
Deposit date:2006-05-13
Release date:2006-06-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
Bioorg.Med.Chem.Lett., 16, 2006
2QLH
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BU of 2qlh by Molmil
mPlum I65L mutant
Descriptor: Fluorescent protein plum
Authors:Shu, X, Remington, S.J.
Deposit date:2007-07-12
Release date:2008-07-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies of Far-Red Emission in mPlum, a Monomeric Red Fluorescent Protein
To be Published
3PG1
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BU of 3pg1 by Molmil
MAP kinase LmaMPK10 from Leishmania major (1.95 angs resolution)
Descriptor: Mitogen-activated protein kinase, putative (Map kinase-like protein)
Authors:Horjales, S, Buschiazzo, A.
Deposit date:2010-10-29
Release date:2011-11-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms.
Structure, 20, 2012
2QAR
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BU of 2qar by Molmil
Structure of the 2TEL crystallization module fused to T4 lysozyme with a helical linker.
Descriptor: AMMONIUM ION, E80-TELSAM domain, Lysozyme, ...
Authors:Nauli, S, Bowie, J.U.
Deposit date:2007-06-15
Release date:2008-01-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Polymer-driven crystallization.
Protein Sci., 16, 2007
2QLG
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BU of 2qlg by Molmil
mPlum
Descriptor: Fluorescent protein plum
Authors:Shu, X, Remington, S.J.
Deposit date:2007-07-12
Release date:2008-07-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Studies of Far-Red Emission in mPlum, a Monomeric Red Fluorescent Protein
To be Published
2QLI
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BU of 2qli by Molmil
mPlum E16Q mutant
Descriptor: Fluorescent protein plum
Authors:Shu, X, Remington, S.J.
Deposit date:2007-07-12
Release date:2008-07-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structural Studies of Far-Red Emission in mPlum, a Monomeric Red Fluorescent Protein
To be Published
2R5O
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BU of 2r5o by Molmil
Crystal structure of the C-terminal domain of wzt
Descriptor: CHLORIDE ION, Putative ATP binding component of ABC-transporter, SODIUM ION, ...
Authors:Kimber, M.S, Cuthbertson, L, Whitfield, C.
Deposit date:2007-09-04
Release date:2007-12-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Substrate binding by a bacterial ABC transporter involved in polysaccharide export.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4EX6
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BU of 4ex6 by Molmil
Crystal structure of the alnumycin P phosphatase AlnB
Descriptor: AlnB, BORIC ACID, MAGNESIUM ION
Authors:Oja, T, Niiranen, L, Sandalova, T, Klika, K.D, Niemi, J, Mantsala, P, Schneider, G, Metsa-Ketela, M.
Deposit date:2012-04-30
Release date:2013-01-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural basis for C-ribosylation in the alnumycin A biosynthetic pathway.
Proc.Natl.Acad.Sci.USA, 110, 2013
2BGM
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BU of 2bgm by Molmil
X-Ray structure of ternary-Secoisolariciresinol Dehydrogenase
Descriptor: MATAIRESINOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), RHIZOME SECOISOLARICIRESINOL DEHYDROGENASE
Authors:Youn, B, Moinuddin, S.G, Davin, L.B, Lewis, N.G, Kang, C.
Deposit date:2004-12-23
Release date:2005-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Apo-Form and Binary/Ternary Complexes of Podophyllum Secoisolariciresinol Dehydrogenase, an Enzyme Involved in Formation of Health-Protecting and Plant Defense Lignans
J.Biol.Chem., 280, 2005
4EHB
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BU of 4ehb by Molmil
Crystal structure of the CFTR inhibitory factor Cif with the D129S mutation bound to epoxyhexane
Descriptor: (2R)-2-butyloxirane, Putative hydrolase
Authors:Hvorecny, K.L, Bahl, C.D, Madden, D.R.
Deposit date:2012-04-02
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif.
Biochemistry, 55, 2016

222624

数据于2024-07-17公开中

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