4EHB

Crystal structure of the CFTR inhibitory factor Cif with the D129S mutation bound to epoxyhexane

Summary for 4EHB

Entry DOI	10.2210/pdb4ehb/pdb
Related	3KD2 3KDA 3PI6 4DLN 4DM7 4DMC 4DMF 4DMH 4DNF 4DNO
Descriptor	Putative hydrolase, (2R)-2-butyloxirane (3 entities in total)
Functional Keywords	alpha beta hydrolase, epoxide hydrolase, secreted, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	4
Total formula weight	136947.40
Authors	Hvorecny, K.L.,Bahl, C.D.,Madden, D.R. (deposition date: 2012-04-02, release date: 2013-08-07, Last modification date: 2017-11-15)
Primary citation	Bahl, C.D.,Hvorecny, K.L.,Morisseau, C.,Gerber, S.A.,Madden, D.R. Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif. Biochemistry, 55:788-797, 2016 Cited by PubMed: 26752215 DOI: 10.1021/acs.biochem.5b01229 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation