4DNF
Crystal structure of the CFTR inhibitory factor Cif with the E153Q mutation adducted with the epibromohydrin hydrolysis intermediate
Summary for 4DNF
Entry DOI | 10.2210/pdb4dnf/pdb |
Related | 3KD2 3KDA 3PI6 4DLN 4DM7 4DMC 4DMF 4DMH 4DMK 4DNO |
Descriptor | Putative hydrolase, (2S)-1-bromopropan-2-ol (3 entities in total) |
Functional Keywords | alpha beta hydrolase, epoxide hydrolase, covalently adducted with the epibromohydrin hydrolysis intermediate, secreted, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 4 |
Total formula weight | 137210.82 |
Authors | Bahl, C.D.,Madden, D.R. (deposition date: 2012-02-08, release date: 2013-08-07, Last modification date: 2023-09-13) |
Primary citation | Bahl, C.D.,Hvorecny, K.L.,Morisseau, C.,Gerber, S.A.,Madden, D.R. Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif. Biochemistry, 55:788-797, 2016 Cited by PubMed: 26752215DOI: 10.1021/acs.biochem.5b01229 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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