PDB: 92137 resultsInfo pagesStatus searchChemie searchBIRD

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3B6W	Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686S Mutant in Complex with Glutamate at 1.7 Resolution Descriptor: GLUTAMIC ACID, Glutamate receptor 2, SULFATE ION Authors: Cho, Y, Lolis, E, Howe, J.R. Deposit date: 2007-10-29 Release date: 2008-02-05 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. J.Neurosci., 28, 2008
1MYJ	DISTAL POLARITY IN LIGAND BINDING TO MYOGLOBIN: STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A THREONINE68(E11) MUTANT Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION Authors: Smerdon, S.J, Oldfield, T.J, Wilkinson, A.J, Dauter, Z, Petratos, K, Wilson, K.S. Deposit date: 1992-02-27 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Distal pocket polarity in ligand binding to myoglobin: structural and functional characterization of a threonine68(E11) mutant. Biochemistry, 30, 1991
1S50	X-ray structure of the GluR6 ligand binding core (S1S2A) in complex with glutamate at 1.65 A resolution Descriptor: GLUTAMIC ACID, Glutamate Receptor 6 Authors: Mayer, M.L. Deposit date: 2004-01-19 Release date: 2005-02-08 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005
5FUO	Extending the half-life of a Fab fragment through generation of a humanised anti-Human Serum Albumin (HSA) Fv domain: an investigation into the correlation between affinity and serum half-life Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, SERUM ALBUMIN Authors: Adams, R, Ceska, T. Deposit date: 2016-01-28 Release date: 2016-06-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Extending the Half-Life of a Fab Fragment Through Generation of a Humanized Anti-Human Serum Albumin Fv Domain: An Investigation Into the Correlation between Affinity and Serum Half-Life. Mabs, 8, 2016
5FUZ	Extending the half-life of a Fab fragment through generation of a humanised anti-Human Serum Albumin (HSA) Fv domain: an investigation into the correlation between affinity and serum half-life Descriptor: 645 FAB, HEAVY CHAIN, LIGHT CHAIN Authors: Adams, R, Ceska, T. Deposit date: 2016-02-01 Release date: 2016-06-29 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Extending the Half-Life of a Fab Fragment Through Generation of a Humanized Anti-Human Serum Albumin Fv Domain: An Investigation Into the Correlation between Affinity and Serum Half-Life. Mabs, 8, 2016
2LKS	Ff11-60 Descriptor: Pre-mRNA-processing factor 40 homolog A Authors: Barette, J, Velyvis, A, Religa, T.L, Korzhnev, D.M, Kay, L.E. Deposit date: 2011-10-19 Release date: 2012-01-11 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Cross-Validation of the Structure of a Transiently Formed and Low Populated FF Domain Folding Intermediate Determined by Relaxation Dispersion NMR and CS-Rosetta. J.Phys.Chem.B, 116, 2012
1SD3	Crystal structure of the GLUR6 ligand binding core in complex with 2S,4R-4-methylglutamate at 1.8 Angstrom resolution Descriptor: 2S,4R-4-METHYLGLUTAMATE, Glutamate receptor, ionotropic kainate 2 Authors: Mayer, M.L. Deposit date: 2004-02-12 Release date: 2005-02-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. Neuron, 45, 2005
3QZX	3D Structure of ferric methanosarcina acetivorans protoglobin Y61A mutant with unknown ligand Descriptor: GLYCEROL, Methanosarcina acetivorans protoglobin, PHOSPHATE ION, ... Authors: Pesce, A, Tilleman, L, Dewilde, S, Ascenzi, P, Coletta, M, Ciaccio, C, Bruno, S, Moens, L, Bolognesi, M, Nardini, M. Deposit date: 2011-03-07 Release date: 2011-06-08 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants. Iubmb Life, 63, 2011
1PBP	FINE TUNING OF THE SPECIFICITY OF THE PERIPLASMIC PHOSPHATE TRANSPORT RECEPTOR: SITE-DIRECTED MUTAGENESIS, LIGAND BINDING, AND CRYSTALLOGRAPHIC STUDIES Descriptor: PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN Authors: Wang, Z, Choudhary, A, Ledvina, P.S, Quiocho, F.A. Deposit date: 1994-07-20 Release date: 1994-10-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Fine tuning the specificity of the periplasmic phosphate transport receptor. Site-directed mutagenesis, ligand binding, and crystallographic studies. J.Biol.Chem., 269, 1994
1YMA	STRUCTURAL CHARACTERIZATION OF HEME LIGATION IN THE HIS64-->TYR VARIANT OF MYOGLOBIN Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION Authors: Maurus, R, Brayer, G.D. Deposit date: 1993-09-27 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural characterization of heme ligation in the His64-->Tyr variant of myoglobin. J.Biol.Chem., 269, 1994
4B2Y	Probing the active center of catalase-phenol oxidase from Scytalidium thermophilum Descriptor: CALCIUM ION, CATALASE-PHENOL OXIDASE, PROTOPORPHYRIN IX CONTAINING FE Authors: Yuzugullu, Y, Trinh, C.H, Pearson, A.R, Ogel, Z.B, McPherson, M.J. Deposit date: 2012-07-19 Release date: 2013-04-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Investigating the Active Centre of the Scytalidium Thermophilum Catalase Acta Crystallogr.,Sect.F, 69, 2013
3TGS	Crystal structure of HIV-1 clade C strain C1086 gp120 core in complex with NBD-556 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade C1086 gp120 core, N-(4-chlorophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)ethanediamide Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2011-08-17 Release date: 2012-04-04 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc.Natl.Acad.Sci.USA, 109, 2012
4B40	Probing the active center of catalase-phenol oxidase from Scytalidium thermophilum Descriptor: CALCIUM ION, CATALASE-PHENOL OXIDASE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE Authors: Yuzugullu, Y, Trinh, C.H, Pearson, A.R, Ogel, Z.B, McPherson, M.J. Deposit date: 2012-07-27 Release date: 2013-04-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Investigating the Active Centre of the Scytalidium Thermophilum Catalase Acta Crystallogr.,Sect.F, 69, 2013
2REA	Crystal structures of C2ALPHA-PI3 kinase PX-domain domain indicate conformational change associated with ligand binding. Descriptor: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide Authors: Parkinson, G.N, Vines, D, Driscoll, P.C, Djordjevic, S. Deposit date: 2007-09-26 Release date: 2007-11-27 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding Bmc Struct.Biol., 8, 2008
2XJA	Structure of MurE from M.tuberculosis with dipeptide and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE, ... Authors: Basavannacharya, C, Moody, P.R, Bhakta, S, Keep, N. Deposit date: 2010-07-03 Release date: 2010-08-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Essential Residues for the Enzyme Activity of ATP-Dependent Mure Ligase from Mycobacterium Tuberculosis. Protein Cell, 1, 2010
4B5K	Probing the active center of catalase-phenol oxidase from Scytalidium thermophilum Descriptor: CALCIUM ION, CATALASE-PHENOL OXIDASE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE Authors: Yuzugullu, Y, Trinh, C.H, Pearson, A.R, Ogel, Z.B, McPherson, M.J. Deposit date: 2012-08-03 Release date: 2013-04-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Investigating the Active Centre of the Scytalidium Thermophilum Catalase Acta Crystallogr.,Sect.F, 69, 2013
4B31	Probing the active center of catalase-phenol oxidase from Scytalidium thermophilum Descriptor: CALCIUM ION, CATALASE-PHENOL OXIDASE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE Authors: Yuzugullu, Y, Trinh, C.H, Pearson, A.R, Ogel, Z.B, McPherson, M.J. Deposit date: 2012-07-20 Release date: 2013-04-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Investigating the Active Centre of the Scytalidium Thermophilum Catalase Acta Crystallogr.,Sect.F, 69, 2013
1OYB	OLD YELLOW ENZYME AT 2 ANGSTROMS RESOLUTION: OVERALL STRUCTURE, LIGAND BINDING AND COMPARISON WITH RELATED FLAVOPROTEINS Descriptor: FLAVIN MONONUCLEOTIDE, OLD YELLOW ENZYME, P-HYDROXYBENZALDEHYDE Authors: Fox, K.M, Karplus, P.A. Deposit date: 1994-08-25 Release date: 1994-11-30 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Old yellow enzyme at 2 A resolution: overall structure, ligand binding, and comparison with related flavoproteins. Structure, 2, 1994
1OYA	OLD YELLOW ENZYME AT 2 ANGSTROMS RESOLUTION: OVERALL STRUCTURE, LIGAND BINDING AND COMPARISON WITH RELATED FLAVOPROTEINS Descriptor: FLAVIN MONONUCLEOTIDE, OLD YELLOW ENZYME Authors: Fox, K.M, Karplus, P.A. Deposit date: 1994-08-25 Release date: 1995-03-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Old yellow enzyme at 2 A resolution: overall structure, ligand binding, and comparison with related flavoproteins. Structure, 2, 1994
5BUE	ERK2 complexed with N-benzylpyridone tetrahydroazaindazole Descriptor: 1-benzyl-4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1H)-one, Mitogen-activated protein kinase 1, NICKEL (II) ION Authors: Bellamacina, C.R, Shu, W, Bussiere, D.E, Bagdanoff, J.T. Deposit date: 2015-06-03 Release date: 2015-07-15 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase. Bioorg.Med.Chem.Lett., 25, 2015
1OYC	OLD YELLOW ENZYME AT 2 ANGSTROMS RESOLUTION: OVERALL STRUCTURE, LIGAND BINDING AND COMPARISON WITH RELATED FLAVOPROTEINS Descriptor: FLAVIN MONONUCLEOTIDE, OLD YELLOW ENZYME Authors: Fox, K.M, Karplus, P.A. Deposit date: 1994-08-25 Release date: 1994-11-30 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Old yellow enzyme at 2 A resolution: overall structure, ligand binding, and comparison with related flavoproteins. Structure, 2, 1994
3OED	The structure of the complex between complement receptor CR2 and its ligand complement fragment C3d Descriptor: Complement C3, Complement receptor type 2 Authors: Isenman, D.E, van den Elsen, J.M.H. Deposit date: 2010-08-12 Release date: 2011-05-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.16 Å) Cite: A crystal structure of the complex between human complement receptor 2 and its ligand C3d. Science, 332, 2011
5FRB	Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with a tetrazole-based inhibitor VT-1598 Descriptor: (R)-4-((4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1H-tetrazol-1-yl)propyl)pyridin-3-yl)ethynyl)phenoxy)methyl)benzonitrile, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE, ... Authors: Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. Deposit date: 2015-12-16 Release date: 2017-04-26 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.99 Å) Cite: Crystal Structure of the New Investigational Drug Candidate VT-1598 in Complex with Aspergillus fumigatus Sterol 14 alpha-Demethylase Provides Insights into Its Broad-Spectrum Antifungal Activity. Antimicrob. Agents Chemother., 61, 2017
2HJE	Crystal structure of Vibrio harveyi LuxQ periplasmic domain Descriptor: Autoinducer 2 sensor kinase/phosphatase luxQ, NICKEL (II) ION Authors: Neiditch, M.B, Kelly, R.C, Hughson, F.M. Deposit date: 2006-06-30 Release date: 2006-09-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing. Cell(Cambridge,Mass.), 126, 2006
1EJC	Crystal structure of unliganded mura (type2) Descriptor: GLYCEROL, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE Authors: Eschenburg, S, Schonbrunn, E. Deposit date: 2000-03-02 Release date: 2000-10-25 Last modified: 2011-07-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Comparative X-ray analysis of the un-liganded fosfomycin-target murA. Proteins, 40, 2000

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