PDB: 221716 resultsInfo pagesStatus searchChemie searchBIRD

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8SXW	X-ray crystal structure of UDP- 2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase from Thermus thermophilus strain HB27, D98N mutation, apo structure at pH 6 Descriptor: CHLORIDE ION, SODIUM ION, UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase Authors: Kroft, C.W, Thoden, J.B, Holden, H.M. Deposit date: 2023-05-24 Release date: 2023-09-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis. J.Biol.Chem., 299, 2023
8SXV	X-ray crystal structure of UDP- 2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase from Thermus thermophilus strain HB27, apo form, pH 9 Descriptor: CHLORIDE ION, UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase Authors: McKnight, J.O, Thoden, J.B, Holden, H.M. Deposit date: 2023-05-24 Release date: 2023-09-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis. J.Biol.Chem., 299, 2023
8SXU	Structure of LINE-1 ORF2p with an oligo(A) template Descriptor: LINE-1 retrotransposable element ORF2 protein, RNA (25-MER) Authors: van Eeuwen, T, Taylor, M.S, Rout, M.P. Deposit date: 2023-05-24 Release date: 2024-01-10 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.66 Å) Cite: Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626, 2024
8SXT	Structure of LINE-1 ORF2p with template:primer hybrid Descriptor: DNA primer, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... Authors: van Eeuwen, T, Taylor, M.S, Rout, M.P. Deposit date: 2023-05-24 Release date: 2024-01-10 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626, 2024
8SXS	Crystal structure of a Nudix hydrolase effector from Magnaporthe oryzae Descriptor: Nudix hydrolase domain-containing protein Authors: McCombe, C.L, Ericsson, D.J, Williams, S.J. Deposit date: 2023-05-23 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Plant pathogenic fungi hijack phosphate starvation signaling with conserved enzymatic effectors Biorxiv, 2023
8SXR	Crystal structure of SARS-CoV-2 Mpro with C5a Descriptor: 3C-like proteinase nsp5, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(5-hydroxyisoquinolin-4-yl)acetamide Authors: Worrall, L.J, Kenward, C, Lee, J, Strynadka, N.C.J. Deposit date: 2023-05-23 Release date: 2023-08-30 Method: X-RAY DIFFRACTION (2.114 Å) Cite: A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
8SXQ	Crystal structure of Sel-1 repeat protein LceB from Legionella pneumophila Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, SEL-1 repeat protein Authors: Penner, T.V, Prehna, G. Deposit date: 2023-05-23 Release date: 2024-01-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural characterization of the Sel1-like repeat protein LceB from Legionella pneumophila. Protein Sci., 33, 2024
8SXP	Crystal structure of long neurotoxin from the venom of the king cobra (3FTx-L15) in complex with Fab of broadly neutralizing antibody 95Mat5 Descriptor: 95Mat5 Fab heavy chain, 95Mat5 Fab light chain, Long neurotoxin 2 Authors: Nguyen, T.K.Y. Deposit date: 2023-05-23 Release date: 2024-03-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Synthetic development of a broadly neutralizing antibody against snake venom long-chain neurotoxins Sci Transl Med, 16, 2024
8SXO	Crystal Structure of SARS-CoV-2 Main Protease (Mpro) H164I Mutant Descriptor: 3C-like proteinase nsp5 Authors: Kohaal, N, Lewandowski, E.M, Wang, J, Chen, Y. Deposit date: 2023-05-23 Release date: 2023-06-14 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Crystal Structure of SARS-CoV-2 Main Protease (Mpro) H164I Mutant To Be Published
8SXN	Structure of NLRP3 and NEK7 complex Descriptor: 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-TRIPHOSPHATE, NACHT, ... Authors: Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S. Deposit date: 2023-05-22 Release date: 2024-02-14 Method: ELECTRON MICROSCOPY (4.04 Å) Cite: Cryo-EM structures of NLRP3 reveal its self-activation mechanism Nat Commun, 2024
8SXM	NMR structure of the ZNF750 zinc finger domain, Z* Descriptor: ZINC ION, Zinc finger protein 750 Authors: Rua, A.J, Alexandrescu, A.T. Deposit date: 2023-05-22 Release date: 2023-08-23 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: NMR structure verifies the eponymous zinc finger domain of transcription factor ZNF750. J Struct Biol X, 8, 2023
8SXL	RNA UU template binding to AMP monomer Descriptor: ADENOSINE MONOPHOSPHATE, RNA (5'-R(*(TLN)P*(TLN)P*(LCA)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*U)-3') Authors: Zhang, W, Dantsu, Y. Deposit date: 2023-05-22 Release date: 2023-05-31 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Insight into the structures of unusual base pairs in RNA complexes containing a primer/template/adenosine ligand. Rsc Chem Biol, 4, 2023
8SXJ	CH505 Disulfide Stapled SOSIP Bound to CH235.12 Fab Descriptor: CH235.12 Heavy Chain, CH235.12 Light Chain, Envelope glycoprotein gp160, ... Authors: Henderson, R. Deposit date: 2023-05-22 Release date: 2024-02-14 Method: ELECTRON MICROSCOPY (4 Å) Cite: Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv, 10, 2024
8SXI	CH505 Disulfide Stapled SOSIP Bound to b12 Fab Descriptor: Envelope glycoprotein gp160, HIV-1 gp41, b12 Heavy Chain, ... Authors: Henderson, R. Deposit date: 2023-05-22 Release date: 2024-02-14 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv, 10, 2024
8SXH	Structure of the C-terminal protease CtpA-LbcA complex of Pseudomonas aeruginosa Descriptor: Carboxyl-terminal protease, TPR repeat-containing protein PA4667, unidentified peptide Authors: Hsu, H.-C, Li, H. Deposit date: 2023-05-22 Release date: 2024-03-06 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.94 Å) Cite: P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process. Embo J., 43, 2024
8SXG	The C-terminal protease CtpA-LbcA complex of pseudomonas aeruginosa with the TPR at the low position Descriptor: Probable carboxyl-terminal protease, TPR repeat-containing protein PA4667, unidentified peptide Authors: Hsu, H.-C, Li, H. Deposit date: 2023-05-22 Release date: 2024-03-06 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (4.14 Å) Cite: P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process. Embo J., 43, 2024
8SXF	The C-terminal protease CtpA-LbcA complex of pseudomonas aeruginosa with the TPR at the high position Descriptor: Probable carboxyl-terminal protease, TPR repeat-containing protein PA4667, polyA Authors: Hsu, H.-C, Li, H. Deposit date: 2023-05-22 Release date: 2024-03-06 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.92 Å) Cite: P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process. Embo J., 43, 2024
8SXE	Structure of the C-terminal protease CtpA-LbcA complex of Pseudomonas aeruginosa Descriptor: Probable carboxyl-terminal protease, TPR repeat-containing protein PA4667, unidentified peptide Authors: Hsu, H.-C, Li, H. Deposit date: 2023-05-22 Release date: 2024-03-06 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.55 Å) Cite: P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process. Embo J., 43, 2024
8SXD	Campylobacter jejuni keto-acid reductoisomerase in complex with intermediate and NADP+ Descriptor: 3-hydroxy-3-methyl-2-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase, ... Authors: Lin, X, Lonhienne, T, Guddat, L.W. Deposit date: 2023-05-21 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase Acs Catalysis, 2024
8SXC	Crystal Structure of Fluorescent Protein Fusion Red 2 Descriptor: Far-red Fluorescent Protein Fusion Red 2, GLYCEROL, HEXAETHYLENE GLYCOL, ... Authors: Pletnev, S, Pletneva, N, Pletnev, V. Deposit date: 2023-05-21 Release date: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of Fluorescent Protein Fusion Red 2 To Be Published
8SXB	Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E2 in MSP lipid nanodisc Descriptor: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Multidrug resistance-associated protein 4 isoform X1 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SXA	Inward-facing wide conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc Descriptor: Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SX9	Inward-facing narrow conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc Descriptor: Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SX8	Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E1 in MSP lipid nanodisc Descriptor: 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid, Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SX7	Bovine multidrug resistance protein 4 (MRP4) bound to DHEA-S in MSP lipid nanodisc Descriptor: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024

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