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6A5U
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BU of 6a5u by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation
Descriptor: DNA (198-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5P
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BU of 6a5p by Molmil
RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5O
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BU of 6a5o by Molmil
RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
7NW0
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BU of 7nw0 by Molmil
RNA polymerase II pre-initiation complex with open promoter DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7NVZ
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BU of 7nvz by Molmil
RNA polymerase II pre-initiation complex with closed promoter DNA in distal position
Descriptor: CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7NVY
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BU of 7nvy by Molmil
RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position
Descriptor: CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7OB9
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BU of 7ob9 by Molmil
Cryo-EM structure of human RNA Polymerase I in elongation state
Descriptor: DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ...
Authors:Misiaszek, A.D, Girbig, M, Mueller, C.W.
Deposit date:2021-04-21
Release date:2021-12-08
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structures of human RNA polymerase I.
Nat.Struct.Mol.Biol., 28, 2021
6YSR
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BU of 6ysr by Molmil
Structure of the P+9 stalled ribosome complex
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
6AGB
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BU of 6agb by Molmil
Cryo-EM structure of yeast Ribonuclease P
Descriptor: RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, Ribonuclease P protein subunit RPR2, ...
Authors:Lan, P, Tan, M, Wu, J, Lei, M.
Deposit date:2018-08-10
Release date:2018-10-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structural insight into precursor tRNA processing by yeast ribonuclease P.
Science, 362, 2018
8H1B
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BU of 8h1b by Molmil
Crystal structure of MnmM from S. aureus complexed with SAM and tRNA anti-codon stem loop (ASL) (1.55 A)
Descriptor: RNA (5'-R(*AP*CP*GP*GP*AP*CP*UP*UP*UP*GP*AP*CP*UP*CP*CP*GP*U)-3'), S-ADENOSYLMETHIONINE, SODIUM ION, ...
Authors:Kim, J, Cho, G, Lee, J.
Deposit date:2022-10-01
Release date:2023-01-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification.
Nucleic Acids Res., 51, 2023
7S7B
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BU of 7s7b by Molmil
Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)
Descriptor: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
7S7C
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BU of 7s7c by Molmil
Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2)
Descriptor: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
5M0I
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BU of 5m0i by Molmil
Crystal structure of the nuclear complex with She2p and the ASH1 mRNA E3-localization element
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ASH1-E3 element, ...
Authors:Edelmann, F.T, Janowski, R, Niessing, D.
Deposit date:2016-10-05
Release date:2017-01-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex.
Nat. Struct. Mol. Biol., 24, 2017
7KEF
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BU of 7kef by Molmil
RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state
Descriptor: (1S)-1,4-anhydro-1-(3-methoxynaphthalen-2-yl)-5-O-phosphono-D-ribitol, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Oh, J, Wang, D.
Deposit date:2020-10-10
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.89 Å)
Cite:Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II.
Nat.Chem.Biol., 17, 2021
7KEE
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BU of 7kee by Molmil
RNA polymerase II elongation complex with unnatural base dTPT3, rNaMTP bound to E-site
Descriptor: (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Oh, J, Wang, D.
Deposit date:2020-10-10
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II.
Nat.Chem.Biol., 17, 2021
8CTI
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BU of 8cti by Molmil
Cryo-EM structure of human METTL1-WDR4-tRNA(Val) complex
Descriptor: tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4, tRNA-Val-TAC-2-1
Authors:Li, J, Wang, L, Fontana, P, Hunkeler, M, Roy-Burman, S.S, Wu, H, Fischer, E.S, Gregory, R.I.
Deposit date:2022-05-14
Release date:2022-12-07
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.
Nature, 613, 2023
7KED
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BU of 7ked by Molmil
RNA polymerase II elongation complex with unnatural base dTPT3
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Oh, J, Wang, W, Wang, D.
Deposit date:2020-10-10
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II.
Nat.Chem.Biol., 17, 2021
6N4O
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BU of 6n4o by Molmil
Human Argonaute2-miR-122 bound to a seed and supplementary paired target
Descriptor: Protein argonaute-2, RNA (5'-R(*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-11-19
Release date:2019-05-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2.
Embo J., 38, 2019
5G5L
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BU of 5g5l by Molmil
RNA polymerase I-Rrn3 complex at 4.8 A resolution
Descriptor: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ...
Authors:Engel, C, Plitzko, J, Cramer, P.
Deposit date:2016-05-26
Release date:2016-07-27
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:RNA Polymerase I-Rrn3 Complex at 4.8 A Resolution
Nat.Commun., 7, 2016
7KI3
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BU of 7ki3 by Molmil
Human Argonaute2:miR-122 bound to the HCV genotype 1a site-1 RNA
Descriptor: BARIUM ION, HCV genotype 1a miR-122 site-1, Protein argonaute-2, ...
Authors:Gebert, L.F.R, MacRae, I.J.
Deposit date:2020-10-22
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:A structured RNA motif locks Argonaute2:miR-122 onto the 5' end of the HCV genome.
Nat Commun, 12, 2021
6HLQ
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BU of 6hlq by Molmil
Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Tafur, L, Sadian, Y, Weis, F, Muller, C.W.
Deposit date:2018-09-11
Release date:2019-04-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.
Elife, 8, 2019
5XON
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BU of 5xon by Molmil
RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS
Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S.
Deposit date:2017-05-29
Release date:2017-08-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.83 Å)
Cite:Structure of the complete elongation complex of RNA polymerase II with basal factors
Science, 357, 2017
6HLR
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BU of 6hlr by Molmil
Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused)
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Tafur, L, Sadian, Y, Weis, F, Muller, C.W.
Deposit date:2018-09-11
Release date:2019-04-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.
Elife, 8, 2019
6HKO
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BU of 6hko by Molmil
Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Tafur, L, Sadian, Y, Weis, F, Muller, C.W.
Deposit date:2018-09-07
Release date:2019-04-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.
Elife, 8, 2019
7ZWD
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BU of 7zwd by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-19
Release date:2022-11-30
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022

222415

数据于2024-07-10公开中

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