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6RXX
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BU of 6rxx by Molmil
Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state C, Poly-Ala
Descriptor: 35S ribosomal RNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ...
Authors:Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
4XXJ
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BU of 4xxj by Molmil
Crystal Structure of Escherichia coli-Expressed Halobacterium salinarum Bacteriorhodopsin in the Trimeric Form
Descriptor: Bacteriorhodopsin, EICOSANE, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
Authors:Bratanov, D, Balandin, T, Round, E, Gushchin, I, Gordeliy, V.
Deposit date:2015-01-30
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An Approach to Heterologous Expression of Membrane Proteins. The Case of Bacteriorhodopsin.
Plos One, 10, 2015
4REU
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BU of 4reu by Molmil
Revelation of Endogenously bound Fe2+ ions in the Crystal Structure of Ferritin from Escherichia coli
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FE (III) ION, ...
Authors:Thiruselvam, V, Ponnuswamy, M.N, Kumarevel, T.S.
Deposit date:2014-09-24
Release date:2014-10-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Revelation of endogenously bound Fe(2+) ions in the crystal structure of ferritin from Escherichia coli.
Biochem.Biophys.Res.Commun., 453, 2014
5NO4
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BU of 5no4 by Molmil
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate with uS3)
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-31
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
6CI0
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BU of 6ci0 by Molmil
Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with E101A (II) mutation
Descriptor: (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ...
Authors:Liu, J, Hiser, C, Ferguson-Miller, S.
Deposit date:2018-02-23
Release date:2018-04-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The K-path entrance in cytochrome c oxidase is defined by mutation of E101 and controlled by an adjacent ligand binding domain.
Biochim. Biophys. Acta, 1859, 2018
6CIE
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BU of 6cie by Molmil
Structure of human endothelial nitric oxide synthase heme domain in complex with N-(1-(2-(Ethyl(methyl)amino)ethyl)-1,2,3,4-tetrahydroquino-lin-6-yl)thiophene-2-carboximidamide
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, CHLORIDE ION, ...
Authors:Chreifi, G, Li, H, Poulos, T.L.
Deposit date:2018-02-23
Release date:2018-10-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for Isoform Selective Nitric Oxide Synthase Inhibition by Thiophene-2-carboximidamides.
Biochemistry, 57, 2018
5NO2
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BU of 5no2 by Molmil
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate)
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-24
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
4QV1
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BU of 4qv1 by Molmil
yCP beta5-M45A mutant
Descriptor: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
Authors:Huber, E.M, Heinemeyer, W, Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QW1
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BU of 4qw1 by Molmil
yCP beta5-A50V mutant in complex with bortezomib
Descriptor: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ...
Authors:Huber, E.M, Heinemeyer, W, Groll, M.
Deposit date:2014-07-16
Release date:2015-02-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4Y0E
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BU of 4y0e by Molmil
X-ray Crystal Structure of a putative dioxygenase from Mycobacterium abscessus
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-02-06
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray Crystal Structure of a putative dioxygenase from Mycobacterium abscessus
to be published
6RKC
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BU of 6rkc by Molmil
Inter-dimeric interface controls function and stability of S-methionine adenosyltransferase from U. urealiticum
Descriptor: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, Methionine adenosyltransferase, ...
Authors:Shahar, A, Zarivach, R, Bershtein, S, Kleiner, D, Shmulevich, F.
Deposit date:2019-04-30
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:The interdimeric interface controls function and stability of Ureaplasma urealiticum methionine S-adenosyltransferase.
J.Mol.Biol., 431, 2019
4Y28
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BU of 4y28 by Molmil
The structure of plant photosystem I super-complex at 2.8 angstrom resolution.
Descriptor: (1R,2S)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
Authors:Mazor, Y, Brovikov, A, Nelson, N.
Deposit date:2015-02-09
Release date:2015-08-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of plant photosystem I super-complex at 2.8 angstrom resolution.
Elife, 4, 2015
4QZZ
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BU of 4qzz by Molmil
yCP in complex with Omuralide
Descriptor: CHLORIDE ION, MAGNESIUM ION, Omuralide, ...
Authors:Huber, E.M, Heinemeyer, W, Groll, M.
Deposit date:2014-07-29
Release date:2015-02-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
6S0O
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BU of 6s0o by Molmil
Crystal Structure of Two-Domain Laccase from Streptomyces griseoflavus produced at 0.25 mM copper sulfate in growth medium
Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, GLYCEROL, ...
Authors:Gabdulkhakov, A.G, Tishchenko, T.V, Kolyadenko, I.A.
Deposit date:2019-06-17
Release date:2019-07-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Investigations of Accessibility of T2/T3 Copper Center of Two-Domain Laccase fromStreptomyces griseoflavusAc-993.
Int J Mol Sci, 20, 2019
6CJU
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BU of 6cju by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cAMP
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel
Authors:Nimigean, C.M, Rheinberger, J.
Deposit date:2018-02-26
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
4R2X
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BU of 4r2x by Molmil
Unique conformation of uridine and asymmetry of the hexameric molecule revealed in the high-resolution structures of Shewanella oneidensis uridine phosphorylase in the free form and in complex with uridine
Descriptor: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
Authors:Safonova, T.N, Mordkovich, N.N, Manuvera, V.A, Veiko, V.P, Popov, V.O, Polyakov, K.M.
Deposit date:2014-08-13
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:High-syn conformation of uridine and asymmetry of the hexameric molecule revealed in the high-resolution structures of Shewanella oneidensis MR-1 uridine phosphorylase in the free form and in complex with uridine.
Acta Crystallogr.,Sect.D, 70, 2014
6CKO
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BU of 6cko by Molmil
Crystal structure of an AF10 fragment
Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10, ...
Authors:Zhang, H, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-28
Release date:2018-03-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.
Genes Dev., 32, 2018
5H11
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BU of 5h11 by Molmil
Crystal structure of Zebrafish Sec10
Descriptor: BROMIDE ION, Uncharacterized protein
Authors:Chen, J, Yamagata, A, Fukai, S.
Deposit date:2016-10-07
Release date:2017-02-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.732 Å)
Cite:Crystal structure of Sec10, a subunit of the exocyst complex
Sci Rep, 7, 2017
5CW7
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BU of 5cw7 by Molmil
Crystal structure of the PaaA2-ParE2 antitoxin-toxin complex
Descriptor: GLYCEROL, PAAA2, Plasmid stabilization protein ParE
Authors:Sterckx, Y.G.-J, Loris, R.
Deposit date:2015-07-27
Release date:2016-06-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.827 Å)
Cite:A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.
J.Mol.Biol., 428, 2016
6S0X
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BU of 6s0x by Molmil
Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22) in complex with erythromycin.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (2.425 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
6CM3
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BU of 6cm3 by Molmil
BG505 SOSIP in complex with sCD4, 17b, 8ANC195
Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, H, Bjorkman, P.J.
Deposit date:2018-03-02
Release date:2018-10-17
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.
Cell Host Microbe, 24, 2018
5CWF
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BU of 5cwf by Molmil
Crystal structure of de novo designed helical repeat protein DHR8
Descriptor: CALCIUM ION, Designed helical repeat protein
Authors:Bhabha, G, Ekiert, D.C.
Deposit date:2015-07-28
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
5GS0
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BU of 5gs0 by Molmil
Crystal structure of the complex of TLR3 and bi-specific diabody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 3, alpha-D-mannopyranose, ...
Authors:Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O.
Deposit date:2016-08-13
Release date:2016-10-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.275 Å)
Cite:Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.
Sci Rep, 6, 2016
5N6S
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BU of 5n6s by Molmil
Thermotoga maritima family 1 Glycoside hydrolase complexed with Carba-Cyclophellitol transition state mimic
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Beta-glucosidase A, ...
Authors:Offen, W, Davies, G.
Deposit date:2017-02-16
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors.
J. Am. Chem. Soc., 139, 2017
6S6X
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BU of 6s6x by Molmil
Structure of Azospirillum brasilense Glutamate Synthase in a6b6 oligomeric state.
Descriptor: FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Chaves-Sanjuan, A, Camilloni, C, Bolognesi, M.
Deposit date:2019-07-03
Release date:2019-09-11
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structures of Azospirillum brasilense Glutamate Synthase in Its Oligomeric Assemblies.
J.Mol.Biol., 431, 2019

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数据于2024-11-06公开中

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