5N6S

Thermotoga maritima family 1 Glycoside hydrolase complexed with Carba-Cyclophellitol transition state mimic

Summary for 5N6S

Entry DOI	10.2210/pdb5n6s/pdb
Descriptor	Beta-glucosidase A, 1,2-ETHANEDIOL, CHLORIDE ION, ... (9 entities in total)
Functional Keywords	hydrolase, carba-cyclophellitol, mimic
Biological source	Thermotoga maritima
Total number of polymer chains	4
Total formula weight	218903.50
Authors	Offen, W.,Davies, G. (deposition date: 2017-02-16, release date: 2017-03-01, Last modification date: 2024-01-17)
Primary citation	Beenakker, T.J.M.,Wander, D.P.A.,Offen, W.A.,Artola, M.,Raich, L.,Ferraz, M.J.,Li, K.Y.,Houben, J.H.P.M.,van Rijssel, E.R.,Hansen, T.,van der Marel, G.A.,Codee, J.D.C.,Aerts, J.M.F.G.,Rovira, C.,Davies, G.J.,Overkleeft, H.S. Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors. J. Am. Chem. Soc., 139:6534-6537, 2017 Cited by PubMed: 28463498 DOI: 10.1021/jacs.7b01773 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation