5U8K
 
 | | RitR mutant - C128S | | Descriptor: | Response regulator | | Authors: | Silvaggi, N.R, Han, L. | | Deposit date: | 2016-12-14 | | Release date: | 2017-12-20 | | Last modified: | 2018-11-28 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
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5M7N
 | | Crystal structure of NtrX from Brucella abortus in complex with ATP processed with the CrystalDirect automated mounting and cryo-cooling technology | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nitrogen assimilation regulatory protein | | Authors: | Cornaciu, I, Fernandez, I, Hoffmann, G, Carrica, M.C, Goldbaum, F.A, Marquez, J.A. | | Deposit date: | 2016-10-28 | | Release date: | 2017-01-25 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Three-Dimensional Structure of Full-Length NtrX, an Unusual Member of the NtrC Family of Response Regulators.
J. Mol. Biol., 429, 2017
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5UXV
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7VE6
 | | N-terminal domain of VraR | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Response regulator protein VraR | | Authors: | Kumar, J.V, Chen, C, Hsu, C.H. | | Deposit date: | 2021-09-08 | | Release date: | 2022-05-18 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus.
Protein Sci., 31, 2022
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6LGQ
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6AZR
 | | Crystal structure of the T264A HK853cp-BeF3-RR468 complex | | Descriptor: | Chemotaxis regulator-transmits chemoreceptor signals to flagelllar motor components CheY, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Rose, J, Zhou, P. | | Deposit date: | 2017-09-11 | | Release date: | 2017-12-27 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.628 Å) | | Cite: | A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases.
Nat Commun, 8, 2017
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8AVX
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8AVV
 | | Cryo-EM structure of DrBphP photosensory module in Pr state | | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome,Response regulator | | Authors: | Wahlgren, W.Y, Takala, H, Westenhoff, S. | | Deposit date: | 2022-08-27 | | Release date: | 2022-12-21 | | Last modified: | 2022-12-28 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural mechanism of signal transduction in a phytochrome histidine kinase.
Nat Commun, 13, 2022
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7LZA
 | | Activated form of VanR from S. coelicolor | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Putative two-component system response regulator | | Authors: | Maciunas, L.J, Loll, P.J. | | Deposit date: | 2021-03-09 | | Release date: | 2021-07-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states.
Acta Crystallogr D Struct Biol, 77, 2021
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7LZ9
 | | Inactive form of VanR from S. coelicolor | | Descriptor: | MAGNESIUM ION, Putative two-component system response regulator | | Authors: | Maciunas, L.J, Loll, P.J. | | Deposit date: | 2021-03-09 | | Release date: | 2021-07-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states.
Acta Crystallogr D Struct Biol, 77, 2021
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6WSH
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6WW6
 | | Crystal structure of EutV bound to RNA | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Response regulator, eutP P2 | | Authors: | Ataide, S.F, Walshe, J.L. | | Deposit date: | 2020-05-07 | | Release date: | 2021-11-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural characterization of the ANTAR antiterminator domain bound to RNA.
Nucleic Acids Res., 50, 2022
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8OYP
 | | Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic | | Descriptor: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I. | | Deposit date: | 2023-05-05 | | Release date: | 2023-10-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity.
J.Biol.Chem., 299, 2023
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8P6F
 | | Crystal structure of PorX-Fj | | Descriptor: | ACETATE ION, MAGNESIUM ION, Response regulator receiver domain-containing protein, ... | | Authors: | Leone, P. | | Deposit date: | 2023-05-26 | | Release date: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure-function analysis of PorX Fj , the PorX homolog from Flavobacterium johnsioniae, suggests a role of the CheY-like domain in type IX secretion motor activity.
Sci Rep, 14, 2024
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8Q52
 | | A PBP-like protein built from fragments of different folds | | Descriptor: | Leucine-specific-binding protein,Chemotaxis protein CheY, SULFATE ION | | Authors: | Shanmugaratnam, S, Toledo-Patino, S, Goetz, S.K, Farias-Rico, J.A, Hocker, B. | | Deposit date: | 2023-08-08 | | Release date: | 2024-04-10 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Molecular handcraft of a well-folded protein chimera.
Febs Lett., 598, 2024
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5M7P
 | | Crystal structure of NtrX from Brucella abortus in complex with ADP processed with the CrystalDirect automated mounting and cryo-cooling technology | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nitrogen assimilation regulatory protein | | Authors: | Cornaciu, I, Fernandez, I, Hoffmann, G, Carrica, M.C, Goldbaum, F.A, Marquez, J.A. | | Deposit date: | 2016-10-28 | | Release date: | 2017-01-25 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Three-Dimensional Structure of Full-Length NtrX, an Unusual Member of the NtrC Family of Response Regulators.
J. Mol. Biol., 429, 2017
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2WB4
 | | activated diguanylate cyclase PleD in complex with c-di-GMP | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), BERYLLIUM TRIFLUORIDE ION, DIGUANYLATE CYCLASE, ... | | Authors: | Wassmann, P, Schirmer, T. | | Deposit date: | 2009-02-20 | | Release date: | 2010-04-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of Activated Pled, Identification of Dimerization and Catalysis Relevant Regulatory Mechanisms
To be Published
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5O8Z
 | | Conformational dynamism for DNA interaction in Salmonella typhimurium RcsB response regulator. | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Transcriptional regulatory protein RcsB | | Authors: | Casino, P, Marina, A, Miguel-Romero, L, Huesa, J. | | Deposit date: | 2017-06-14 | | Release date: | 2017-11-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator.
Nucleic Acids Res., 46, 2018
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5O8Y
 | | Conformational dynamism for DNA interaction in Salmonella typhimurium RcsB response regulator. | | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, SULFATE ION, Transcriptional regulatory protein RcsB | | Authors: | Casino, P, Marina, A, Miguel-Romero, L, Huesa, J. | | Deposit date: | 2017-06-14 | | Release date: | 2017-11-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator.
Nucleic Acids Res., 46, 2018
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4B09
 | | Structure of unphosphorylated BaeR dimer | | Descriptor: | HEXATANTALUM DODECABROMIDE, TRANSCRIPTIONAL REGULATORY PROTEIN BAER | | Authors: | Choudhury, H, Beis, K. | | Deposit date: | 2012-06-29 | | Release date: | 2013-07-10 | | Last modified: | 2013-09-25 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The Dimeric Form of the Unphosphorylated Response Regulator Baer.
Protein Sci., 22, 2013
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7SSI
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7SSJ
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3A0R
 | | Crystal structure of histidine kinase ThkA (TM1359) in complex with response regulator protein TrrA (TM1360) | | Descriptor: | MERCURY (II) ION, Response regulator, Sensor protein | | Authors: | Yamada, S, Sugimoto, H, Kobayashi, M, Ohno, A, Nakamura, H, Shiro, Y. | | Deposit date: | 2009-03-24 | | Release date: | 2009-10-20 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structure of PAS-linked histidine kinase and the response regulator complex
Structure, 17, 2009
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4CBV
 | | X-ray structure of full-length ComE from Streptococcus pneumoniae. | | Descriptor: | COME | | Authors: | Boudes, M, Durand, D, Graille, M, van Tilbeurgh, H, Quevillon-Cheruel, S. | | Deposit date: | 2013-10-16 | | Release date: | 2014-02-12 | | Last modified: | 2014-05-14 | | Method: | X-RAY DIFFRACTION (3.39 Å) | | Cite: | Structural Insights Into the Dimerization of the Response Regulator Come from Streptococcus Pneumoniae.
Nucleic Acids Res., 42, 2014
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4QIC
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