PDB: 347 resultsInfo pagesStatus searchChemie searchBIRD

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3EBM	Crystal structure of human translationally controlled tumour associated protein (hTCTP) mutant E12V Descriptor: Translationally-controlled tumor protein Authors: Yang, B, Dong, X, Zhong, C, Ding, J. Deposit date: 2008-08-28 Release date: 2009-06-30 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Molecular basis of the acceleration of the GDP-GTP exchange of human ras homolog enriched in brain by human translationally controlled tumor protein. J.Biol.Chem., 284, 2009
8AE6	Cryo-EM structure of the SEA complex wing (SEACIT) Descriptor: Maintenance of telomere capping protein 5, Nitrogen permease regulator 2, Nitrogen permease regulator 3, ... Authors: Tafur, L, Loewith, R. Deposit date: 2022-07-12 Release date: 2022-11-02 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Cryo-EM structure of the SEA complex. Nature, 611, 2022
8ADL	Cryo-EM structure of the SEA complex Descriptor: Maintenance of telomere capping protein 5, Nitrogen permease regulator 2, Nitrogen permease regulator 3, ... Authors: Tafur, L, Loewith, R. Deposit date: 2022-07-08 Release date: 2022-11-02 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: Cryo-EM structure of the SEA complex. Nature, 611, 2022
8QB8	Lsp1 in native eisosome lattice bound to plasma membrane microdomain Descriptor: Sphingolipid long chain base-responsive protein LSP1 Authors: Kefauver, J.M, Zou, L, Loewith, R.J, Defosses, A. Deposit date: 2023-08-24 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: CryoEM architecture of a native stretch-sensitive membrane microdomain To Be Published
8QB7	Pil1 in native eisosome lattice bound to plasma membrane microdomain Descriptor: Sphingolipid long chain base-responsive protein PIL1 Authors: Kefauver, J.M, Zou, L, Loewith, R.J, Defosses, A. Deposit date: 2023-08-24 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: CryoEM architecture of a native stretch-sensitive membrane microdomain To Be Published
5NNY	Crystal structure of the phosphatase domain from the Legionella effector WipB Descriptor: WipB Authors: Pinotsis, N, Waksman, G, Prevost, M.S. Deposit date: 2017-04-10 Release date: 2017-09-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery. Sci Rep, 7, 2017
7VV9	Crystal Structure of HRas(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Zheng, Y.Y, Zhou, C. Deposit date: 2021-11-05 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
7VVG	Crystal Structure of HRasG12V(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Zheng, Y.Y, Zhou, C. Deposit date: 2021-11-06 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
7VV8	Crystal Structure of HRasQ61L(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Zheng, Y.Y, Zhou, C. Deposit date: 2021-11-04 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
7VVB	Crystal Structure of KRas4A(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Zheng, Y.Y, Zhou, C. Deposit date: 2021-11-05 Release date: 2022-05-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
6C08	Zebrafish SLC38A9 with arginine bound in the cytosol open state Descriptor: ARGININE, Sodium-coupled neutral amino acid transporter 9, antibody Fab Heavy Chain, ... Authors: Lei, H.-T, Gonen, T. Deposit date: 2017-12-28 Release date: 2018-06-20 Method: X-RAY DIFFRACTION (3.17 Å) Cite: Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state. Nat. Struct. Mol. Biol., 25, 2018
3WDZ	Crystal Structure of Keap1 in Complex with phosphorylated p62 Descriptor: Kelch-like ECH-associated protein 1, Peptide from Sequestosome-1 Authors: Fukutomi, T, Takagi, K, Mizushima, T, Tanaka, K, Komatsu, M, Yamamoto, M. Deposit date: 2013-06-26 Release date: 2013-09-04 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol.Cell, 51, 2013
6MIU	Crystal structure of p62 ZZ domain in complex with Arg-Glu peptide Descriptor: Sequestosome-1, Arg-Glu peptide chimera, ZINC ION Authors: Ahn, J, Zhang, Y, Kutateladze, T.G. Deposit date: 2018-09-20 Release date: 2018-10-31 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: ZZ-dependent regulation of p62/SQSTM1 in autophagy. Nat Commun, 9, 2018
6MJ7	Crystal structure of p62 ZZ domain in complex with free arginine Descriptor: 1,4-DIETHYLENE DIOXIDE, ARGININE, Sequestosome-1, ... Authors: Ahn, J, Zhang, Y, Kutateladze, T.G. Deposit date: 2018-09-20 Release date: 2018-10-31 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.412 Å) Cite: ZZ-dependent regulation of p62/SQSTM1 in autophagy. Nat Commun, 9, 2018
6PW3	LARP1 DM15 FYRE (F844Y, R847E) mutant bound to m7GpppG dinucleotide (capG) Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, La-related protein 1, MAGNESIUM ION Authors: Lahr, R.M, Berman, A.J. Deposit date: 2019-07-22 Release date: 2019-11-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Capturing the Mechanism Underlying TOP mRNA Binding to LARP1. Structure, 27, 2019
8GXP	Complex structure of RORgama with betulinic acid Descriptor: Betulinic acid, Nuclear receptor ROR-gamma Authors: Zhang, X.L, Xu, C, Bai, F. Deposit date: 2022-09-20 Release date: 2023-06-07 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR gamma antagonists. Eur.J.Med.Chem., 257, 2023
8TXS	Solution NMR structure of designed peptide BH26 (RGVTVPHNGESKDYSV) Descriptor: BH26 peptide Authors: McShan, A.C, Torres, M.P. Deposit date: 2023-08-24 Release date: 2023-09-06 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Generative beta-hairpin design using a residue-based physicochemical property landscape. Biophys.J., 2024
2RVK	Refined solution structure of Schizosaccharomyces pombe Sin1 CRIM domain Descriptor: Stress-activated map kinase-interacting protein 1 Authors: Furuita, K, Kataoka, S, Shiozaki, K, Kojima, C. Deposit date: 2015-12-10 Release date: 2017-01-25 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit. Elife, 6, 2017
5HIU	Structure of the TSC2 N-terminus Descriptor: GTPase activator-like protein Authors: Zech, R, Kiontke, S, Kummel, D. Deposit date: 2016-01-12 Release date: 2016-08-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis. J.Biol.Chem., 291, 2016
5OQT	Crystal structure of a bacterial cationic amino acid transporter (CAT) homologue Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, ALANINE, ... Authors: Jungnickel, K.E.J, Newstead, S. Deposit date: 2017-08-14 Release date: 2018-02-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Structural basis for amino acid transport by the CAT family of SLC7 transporters. Nat Commun, 9, 2018
4PSI	PIH1D1/phospho-Tel2 complex Descriptor: PIH1 domain-containing protein 1, Telomere length regulation protein TEL2 homolog Authors: Smerdon, S.J, Boulton, S.J, Stach, L, Flower, T.G, Horejsi, Z. Deposit date: 2014-03-07 Release date: 2014-04-23 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex. Cell Rep, 7, 2014
4PSF	PIH1D1 N-terminal domain Descriptor: PIH1 domain-containing protein 1 Authors: Smerdon, S.J, Boulton, S.J, Stach, L, Flower, T.G, Horejsi, Z. Deposit date: 2014-03-07 Release date: 2014-04-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.578 Å) Cite: Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex. Cell Rep, 7, 2014
6QI9	Truncated human R2TP complex, structure 4 (ADP-empty) Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 Authors: Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. Deposit date: 2019-01-18 Release date: 2019-05-15 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.63 Å) Cite: Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
6QI8	Truncated human R2TP complex, structure 3 (ADP-filled) Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 Authors: Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. Deposit date: 2019-01-18 Release date: 2019-04-10 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
6ZEC	Crystal Structure of the Fab Fragment of a Glycosylated Lymphoma Antibody Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment heavy chain, Fab fragment light chain, ... Authors: Allen, J.D, Watanabe, Y, Crispin, M, Bowden, T.A. Deposit date: 2020-06-16 Release date: 2021-06-30 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior. Blood, 138, 2021

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