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6CYJ
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BU of 6cyj by Molmil
Mycobacterium tuberculosis transcriptional regulator
Descriptor: HTH-type transcriptional regulator PrpR, IRON/SULFUR CLUSTER, SUCCINYL-COENZYME A
Authors:Tang, S, Sacchettini, J.
Deposit date:2018-04-05
Release date:2019-04-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor.
Nucleic Acids Res., 47, 2019
3U9R
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BU of 3u9r by Molmil
Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC), beta subunit
Descriptor: Methylcrotonyl-CoA carboxylase, beta-subunit, PENTAETHYLENE GLYCOL, ...
Authors:Huang, C.S, Tong, L.
Deposit date:2011-10-19
Release date:2011-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase
Nature, 481, 2012
6CZ6
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BU of 6cz6 by Molmil
Mycobacterium tuberculosis transcriptional regulator
Descriptor: COENZYME A, HTH-type transcriptional regulator PrpR, IRON/SULFUR CLUSTER
Authors:Tang, S, Sacchettini, J.
Deposit date:2018-04-08
Release date:2019-04-17
Last modified:2019-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor.
Nucleic Acids Res., 47, 2019
3UB4
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BU of 3ub4 by Molmil
S180L variant of TIR domain of Mal/TIRAP
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Toll/interleukin-1 receptor domain-containing adapter protein
Authors:Shen, Y, Lin, Z.
Deposit date:2011-10-23
Release date:2012-05-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 Signaling
Plos One, 7, 2012
6CN5
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BU of 6cn5 by Molmil
HUMAN RETENOID-RELATED ORPHAN RECEPTOR-GAMMA LIGAND- BINDING DOMAIN IN COMPLEX WITH INDOLE LIGAND CP9b IN INVERSE AGONIST CONFORMATION
Descriptor: 4-cyano-N-{3-[1-(cyclohexanecarbonyl)piperidin-4-yl]-1-methyl-1H-indol-5-yl}pyridine-2-carboxamide, Nuclear receptor ROR-gamma
Authors:Kauppi, B, Vajdos, F.
Deposit date:2018-03-07
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist.
J. Med. Chem., 61, 2018
3FJ8
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BU of 3fj8 by Molmil
Crystal structure of C117I mutant of Human acidic fibroblast growth factor
Descriptor: Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
3HRO
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BU of 3hro by Molmil
Crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2)
Descriptor: Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2), also called Polycystin-2 or polycystic kidney disease 2(PKD2)
Authors:Yu, Y, Ulbrich, M.H, Li, M.-H, Buraei, Z, Chen, X.-Z, Ong, A.C.M, Tong, L, Isacoff, E.Y, Yang, J.
Deposit date:2009-06-09
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and molecular basis of the assembly of the TRPP2/PKD1 complex.
Proc.Natl.Acad.Sci.USA, 106, 2009
3HNM
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Crystal Structure of Protein BT_411 (putative chitobiase, fragment 298-461) from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR319D
Descriptor: MAGNESIUM ION, Putative chitobiase
Authors:Kuzin, A, Abashidze, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Foote, E.L, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-05-31
Release date:2009-07-07
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Northeast Structural Genomics Consortium Target BtR319D
To be published
3HRN
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BU of 3hrn by Molmil
crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2)
Descriptor: Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2)
Authors:Yu, Y, Ulbrich, M.H, Li, M.-H, Buraei, Z, Chen, X.-Z, Ong, A.C.M, Tong, L, Isacoff, E.Y, Yang, J.
Deposit date:2009-06-09
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and molecular basis of the assembly of the TRPP2/PKD1 complex.
Proc.Natl.Acad.Sci.USA, 106, 2009
3VGT
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BU of 3vgt by Molmil
Wild-type nucleoside diphosphate kinase derived from Halomonas sp. 593
Descriptor: Nucleoside diphosphate kinase
Authors:Okazaki, N, Yonezawa, Y, Arai, S, Matsumoto, F, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R.
Deposit date:2011-08-21
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural mechanism for dimeric to tetrameric oligomer conversion in Halomonas sp. nucleoside diphosphate kinase
Protein Sci., 21, 2012
3VKW
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BU of 3vkw by Molmil
Crystal Structure of the Superfamily 1 Helicase from Tomato Mosaic Virus
Descriptor: Replicase large subunit, SULFATE ION
Authors:Nishikiori, M, Sugiyama, S, Xiang, H, Niiyama, M, Ishibashi, K, Inoue, T, Ishikawa, M, Matsumura, H, Katoh, E.
Deposit date:2011-11-22
Release date:2012-07-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the superfamily 1 helicase from tomato mosaic virus
J.Virol., 86, 2012
3VQK
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BU of 3vqk by Molmil
Small heat shock protein hsp14.0 of wild type
Descriptor: Small heat shock protein StHsp14.0
Authors:Hanazono, Y, Takeda, K, Miki, K.
Deposit date:2012-03-26
Release date:2012-06-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural studies on the oligomeric transition of a small heat shock protein, StHsp14.0
J.Mol.Biol., 422, 2012
3I2E
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BU of 3i2e by Molmil
Crystal structure of human dimethylarginine dymethylaminohydrolase-1 (DDAH-1)
Descriptor: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
Authors:Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Robertus, J.D, Fast, W.
Deposit date:2009-06-29
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Biochemistry, 48, 2009
1KGK
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BU of 1kgk by Molmil
Direct Observation of a Cytosine Analog that Forms Five Hydrogen Bonds to Guanosine; Guanyl G-Clamp
Descriptor: 5'-D(*GP*(GCK)P*GP*TP*AP*TP*AP*CP*GP*C)-3', METHOXY-ETHOXYL, SPERMINE (FULLY PROTONATED FORM)
Authors:Wilds, C.J, Maier, M.A, Tereshko, V, Manoharan, M, Egli, M.
Deposit date:2001-11-27
Release date:2001-12-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1 Å)
Cite:Direct Observation of a Cytosine Analogue that Forms Five Hydrogen Bonds to Guanosine: Guanidino G-Clamp
Angew.Chem.Int.Ed.Engl., 41, 2002
3VXU
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BU of 3vxu by Molmil
The complex between T36-5 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide
Descriptor: 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A.
Deposit date:2012-09-20
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
SCI REP, 3, 2013
3IAV
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BU of 3iav by Molmil
Propionyl-CoA Carboxylase Beta Subunit, D422V
Descriptor: Propionyl-CoA carboxylase complex B subunit, SULFATE ION
Authors:Diacovich, L, Arabolaza, A, Shillito, E.M, Lin, T.-W, Mitchell, D.L, Pham, H, Melgar, M.M.
Deposit date:2009-07-14
Release date:2010-06-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor.
Biochemistry, 49, 2010
3I7Y
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BU of 3i7y by Molmil
High pressure structure of I106A variant of RNase A (0.48 GPa)
Descriptor: CHLORIDE ION, Ribonuclease pancreatic
Authors:Lewinski, K, Kurpiewska, K, Dziubek, K, Katrusiak, A, Font, J, Ribo, M, Vilanova, M.
Deposit date:2009-07-09
Release date:2009-08-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural investigation of ribonuclease A conformational preferences using high pressure protein crystallography
Chem.Phys., 468, 2016
3VQM
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BU of 3vqm by Molmil
Small heat shock protein hsp14.0 of C-terminal deletion variant with C-terminal peptide
Descriptor: C-terminal peptide from Small heat shock protein StHsp14.0, Small heat shock protein StHsp14.0
Authors:Hanazono, Y, Takeda, K, Miki, K.
Deposit date:2012-03-26
Release date:2012-06-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural studies on the oligomeric transition of a small heat shock protein, StHsp14.0
J.Mol.Biol., 422, 2012
3VZ7
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BU of 3vz7 by Molmil
Crystal Structure Analysis of the mini-chaperonin variant with Pro 187 Gly
Descriptor: 60 kDa chaperonin
Authors:Saijo, S, Sato, T.
Deposit date:2012-10-09
Release date:2013-11-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding Energy(BE) from Crystal Packing of Mini-chaperones (mcpn) Provided Insights into the Allosteric Interaction of GroEL/ES Complex
To be Published
3IL3
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BU of 3il3 by Molmil
Structure of Haemophilus influenzae FabH
Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 3
Authors:Gajiwala, K.S, Margosiak, S, Lu, J, Cortez, J, Su, Y, Nie, Z, Appelt, K.
Deposit date:2009-08-06
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme.
Febs Lett., 583, 2009
3IMD
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BU of 3imd by Molmil
Crystal Structure of the Grb2 SH2 Domain in Complex with a Flexible Ac-pY-Q-N-NH2 Tripeptide Mimic
Descriptor: CHLORIDE ION, Growth factor receptor-bound protein 2, MAGNESIUM ION, ...
Authors:Clements, J.H.
Deposit date:2009-08-10
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
J.Am.Chem.Soc., 131, 2009
3ILV
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BU of 3ilv by Molmil
Crystal structure of a glutamine-dependent NAD(+) synthetase from Cytophaga hutchinsonii
Descriptor: Glutamine-dependent NAD(+) synthetase
Authors:Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2009-08-07
Release date:2009-08-18
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal structure of a glutamine-dependent NAD(+) synthetase from Cytophaga hutchinsonii
To be Published
2KDP
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BU of 2kdp by Molmil
Solution Structure of the SAP30 zinc finger motif
Descriptor: Histone deacetylase complex subunit SAP30, ZINC ION
Authors:He, Y, Imhoff, R, Sahu, A, Radhakrishnan, I.
Deposit date:2009-01-14
Release date:2009-03-17
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of a novel zinc finger motif in the SAP30 polypeptide of the Sin3 corepressor complex and its potential role in nucleic acid recognition
Nucleic Acids Res., 37, 2009
3F6A
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BU of 3f6a by Molmil
Crystal structure of a hydrolase, NUDIX family from Clostridium perfringens
Descriptor: Hydrolase, NUDIX family
Authors:Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2008-11-05
Release date:2008-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structure of a hydrolase, NUDIX family from Clostridium perfringens
To be Published
3FJD
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BU of 3fjd by Molmil
Crystal structure of L44F/F132W mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009

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数据于2024-09-11公开中

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