PDB: 17012 resultsInfo pagesStatus searchChemie searchBIRD

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3QB0	Crystal structure of Actin-related protein Arp4 from S. cerevisiae complexed with ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 4, CALCIUM ION Authors: Fenn, S, Breitsprecher, D, Gerhold, C.B, Witte, G, Faix, J, Hopfner, K.P. Deposit date: 2011-01-12 Release date: 2011-05-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.404 Å) Cite: Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin. Embo J., 30, 2011
3OC6	Crystal structure of 6-phosphogluconolactonase from mycobacterium smegmatis, apo form Descriptor: 6-phosphogluconolactonase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-09 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QK8	Crystal structure of enoyl-coA hydratase EchA15 from Mycobacterium marinum in complex with an unknown ligand Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Enoyl-CoA hydratase EchA15, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-01-31 Release date: 2011-02-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QIV	Crystal structure of a putative short-chain dehydrogenase or 3-oxoacyl-[acyl-carrier-protein] reductase from Mycobacterium paratuberculosis ATCC BAA-968 / K-10 Descriptor: short-chain dehydrogenase or 3-oxoacyl-[acyl-carrier-protein] reductase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-01-27 Release date: 2011-02-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3Q8N	Crystal structure of 4-aminobutyrate transaminase from Mycobacterium smegmatis Descriptor: 4-aminobutyrate transaminase, 4-oxobutanoic acid Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-01-06 Release date: 2011-02-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3P2Y	Crystal structure of alanine dehydrogenase/pyridine nucleotide transhydrogenase from Mycobacterium smegmatis Descriptor: 1,2-ETHANEDIOL, Alanine dehydrogenase/pyridine nucleotide transhydrogenase, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-10-04 Release date: 2010-10-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3OME	Crystal structure of a probable ENOYL-COA Hydratase from Mycobacterium Smegmatis Descriptor: Enoyl-CoA hydratase, ZINC ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-26 Release date: 2010-09-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QK2	Structure-Based Analysis of the Interaction between the Simian Virus 40 T-Antigen Origin Binding Domain and Single-Stranded DNA Descriptor: Large T antigen, THIOCYANATE ION Authors: Meinke, G, Bullock, P.A, Bohm, A. Deposit date: 2011-01-31 Release date: 2011-02-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.643 Å) Cite: Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA. J.Virol., 85, 2011
3QKA	Crystal structure of enoyl-CoA hydratase EchA5 from Mycobacterium marinum Descriptor: Enoyl-CoA hydratase, EchA5 Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-01-31 Release date: 2011-02-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QLJ	Crystal structure of a short chain dehydrogenase from Mycobacterium avium Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-02-02 Release date: 2011-02-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QXI	Crystal structure of enoyl-CoA hydratase EchA1 from Mycobacterium marinum Descriptor: Enoyl-CoA hydratase EchA1 Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-03-01 Release date: 2011-03-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QDF	Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from Mycobacterium marinum Descriptor: 1,2-ETHANEDIOL, 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, ZINC ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-01-18 Release date: 2011-02-02 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QXZ	Crystal structure of a probable enoyl-CoA hydratase/isomerase from Mycobacterium abscessus Descriptor: 1,2-ETHANEDIOL, GLYCEROL, POTASSIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-03-02 Release date: 2011-03-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QBP	Crystal structure of fumarase Fum from Mycobacterium marinum Descriptor: Fumarase Fum Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-01-13 Release date: 2011-01-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4UJA	Protein Kinase A in complex with an Inhibitor Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-{(3S,4R)-4-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}quinazolin-4(3H)-one, BROMIDE ION, ... Authors: Alam, K.A, Engh, R.A. Deposit date: 2015-04-09 Release date: 2016-04-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
4UJ2	Protein Kinase A in complex with an Inhibitor Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-(3-iodanylphenyl)carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ... Authors: Alam, K.A, Engh, R.A. Deposit date: 2015-04-07 Release date: 2016-04-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.019 Å) Cite: Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
4UJB	Protein Kinase A in complex with an Inhibitor Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-(3-fluorophenyl)carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ... Authors: Alam, K.A, Engh, R.A. Deposit date: 2015-04-09 Release date: 2016-04-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.949 Å) Cite: Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
6XF1	Nesprin-2G(aa1425-1649)-FHOD1(aa1-339) complex, H. sapiens Descriptor: FH1/FH2 domain-containing protein 1, Nesprin-2 Authors: Lim, S.M, Schwartz, T.U. Deposit date: 2020-06-15 Release date: 2021-02-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins. Structure, 29, 2021
4UJ9	Protein Kinase A in complex with an Inhibitor Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-[4-(trifluoromethyl)phenyl]carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Alam, K.A, Engh, R.A. Deposit date: 2015-04-09 Release date: 2016-04-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
8CRH	Crystal structure of Candida auris dihydrofolate reductase complexed with NADPH and cycloguanil Descriptor: 5-(4-chlorophenyl)-6,6-dimethyl-1,4-dihydro-1,3,5-triazine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Kirkman, T.J, Dias, M.V.B. Deposit date: 2023-03-08 Release date: 2023-08-02 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystal structure of dihydrofolate reductase from the emerging pathogenic fungus Candida auris. Acta Crystallogr D Struct Biol, 79, 2023
4UJ1	Protein Kinase A in complex with an Inhibitor Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-(3-chlorophenyl)carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ... Authors: Alam, K.A, Engh, R.A. Deposit date: 2015-04-07 Release date: 2016-04-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.768 Å) Cite: Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
6XF2	Nesprin-1G (aa2070-2200)-FHOD1(aa1-339) complex, H. sapiens Descriptor: FH1/FH2 domain-containing protein 1, Nesprin-1 Authors: Lim, S.M, Schwartz, T.U. Deposit date: 2020-06-15 Release date: 2021-02-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (7.11 Å) Cite: Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins. Structure, 29, 2021
6XIH	Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3 character and an exquisite selectivity profile Descriptor: (2R)-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}oxane-2-carboxamide, Mitogen-activated protein kinase kinase kinase 5 Authors: Dougan, D.R. Deposit date: 2020-06-19 Release date: 2020-08-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3character and an exquisite selectivity profile. Bioorg.Med.Chem.Lett., 30, 2020
6XJK	JAK2 JH2 in complex with JAK067 Descriptor: 4-({4-amino-6-[(1H-indol-5-yl)oxy]-1,3,5-triazin-2-yl}amino)benzene-1-sulfonamide, Tyrosine-protein kinase JAK2 Authors: Puleo, D.E, Krimmer, S.G, Newton, A.S, Schlessinger, J, Jorgensen, W.L. Deposit date: 2020-06-24 Release date: 2020-11-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.023508 Å) Cite: Explicit Representation of Cation-pi Interactions in Force Fields with 1/r4 Nonbonded Terms. J Chem Theory Comput, 16, 2020
4Q96	CID of human RPRD1B in complex with an unmodified CTD peptide Descriptor: RPB1-CTD, Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, ... Authors: Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) Deposit date: 2014-04-29 Release date: 2014-06-04 Last modified: 2014-08-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014

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