4MER
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![BU of 4mer by Molmil](/molmil-images/mine/4mer) | Crystal structure of the novel protein and virulence factor sHIP (Q99XU0) from Streptococcus pyogenes | Descriptor: | streptococcal Histidine-rich glycoprotein Interacting Protein | Authors: | Wisniewska, M, Happonen, L, Frick, M.-I, Bjorck, L, Streicher, W, Malmstrom, J, Wikstrom, M. | Deposit date: | 2013-08-27 | Release date: | 2014-05-21 | Last modified: | 2014-07-16 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Functional and Structural Properties of a Novel Protein and Virulence Factor (Protein sHIP) in Streptococcus pyogenes. J.Biol.Chem., 289, 2014
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2NX8
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3T40
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![BU of 3t40 by Molmil](/molmil-images/mine/3t40) | Crystal Structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) complex with N-2-Carboxyphenyl Glycine (CPG) | Descriptor: | 2-[(carboxymethyl)amino]benzoic acid, Indole-3-glycerol phosphate synthase, SULFATE ION | Authors: | Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2011-07-25 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published
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5XBL
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![BU of 5xbl by Molmil](/molmil-images/mine/5xbl) | Structure of nuclease in complex with associated protein | Descriptor: | Associated protein, CRISPR-associated endonuclease Cas9/Csn1, RNA (98-MER) | Authors: | Dong, D, Guo, M, Wang, S, Zhu, Y, Huang, Z. | Deposit date: | 2017-03-20 | Release date: | 2017-06-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.052 Å) | Cite: | Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein Nature, 546, 2017
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3AIG
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![BU of 3aig by Molmil](/molmil-images/mine/3aig) | ADAMALYSIN II WITH PEPTIDOMIMETIC INHIBITOR POL656 | Descriptor: | (3R)-2-[N-(furan-2-ylcarbonyl)-L-leucyl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid, ADAMALYSIN II, CALCIUM ION, ... | Authors: | Gomis-Rueth, F.X, Meyer, E.F, Kress, L.F, Politi, V. | Deposit date: | 1997-10-12 | Release date: | 1998-04-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor alpha convertase inhibitors. Protein Sci., 7, 1998
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4NSM
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![BU of 4nsm by Molmil](/molmil-images/mine/4nsm) | crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group A Streptococcus | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Collagen-like protein SclB, SULFATE ION | Authors: | Berisio, R, Squeglia, F, Lukomski, S, Bachert, B. | Deposit date: | 2013-11-28 | Release date: | 2013-12-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Crystal Structure of the Streptococcal Collagen-like Protein 2 Globular Domain from Invasive M3-type Group A Streptococcus Shows Significant Similarity to Immunomodulatory HIV Protein gp41. J.Biol.Chem., 289, 2014
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4NT9
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![BU of 4nt9 by Molmil](/molmil-images/mine/4nt9) | Crystal structure of an L,D-carboxypeptidase DacB from Streptococcus pneumonia | Descriptor: | ACETATE ION, GLYCEROL, Putative uncharacterized protein, ... | Authors: | Yang, Y.H, Zhang, J, Jiang, Y.L, Zhou, C.Z, Chen, Y. | Deposit date: | 2013-12-02 | Release date: | 2014-11-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.705 Å) | Cite: | Crystal structure of an L,D-carboxypeptidase DacB from Streptococcus pneumonia To be Published
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3TC6
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![BU of 3tc6 by Molmil](/molmil-images/mine/3tc6) | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR63. | Descriptor: | DI(HYDROXYETHYL)ETHER, Indole-3-glycerol phosphate synthase, PHOSPHATE ION | Authors: | Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-08-08 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design. J.Mol.Biol., 426, 2014
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3TC7
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![BU of 3tc7 by Molmil](/molmil-images/mine/3tc7) | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR62. | Descriptor: | ACETIC ACID, Indole-3-glycerol phosphate synthase, PHOSPHATE ION | Authors: | Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-08-08 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design. J.Mol.Biol., 426, 2014
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1PII
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5XJ1
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![BU of 5xj1 by Molmil](/molmil-images/mine/5xj1) | Crystal structure of spRlmCD | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HEXAETHYLENE GLYCOL, ... | Authors: | Jiang, Y, Gong, Q. | Deposit date: | 2017-04-28 | Release date: | 2017-11-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.753 Å) | Cite: | Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD PLoS ONE, 12, 2017
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6MCB
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5XJ2
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![BU of 5xj2 by Molmil](/molmil-images/mine/5xj2) | Structure of spRlmCD with U747 RNA | Descriptor: | RNA (5'-R(*GP*GP*CP*AP*CP*GP*UP*GP*CP*U)-3'), S-ADENOSYL-L-HOMOCYSTEINE, Uncharacterized RNA methyltransferase SP_1029, ... | Authors: | Jiang, Y, Gong, Q. | Deposit date: | 2017-04-28 | Release date: | 2017-11-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD PLoS ONE, 12, 2017
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4OGD
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3TSM
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4OKM
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![BU of 4okm by Molmil](/molmil-images/mine/4okm) | Selinadiene Synthase apo and in complex with diphosphate | Descriptor: | MAGNESIUM ION, PYROPHOSPHATE, Terpene synthase metal-binding domain-containing protein | Authors: | Baer, P, Rabe, P, Fischer, K, Citron, C.A, Klapschinski, T, Groll, M, Dickschat, J.S. | Deposit date: | 2014-01-22 | Release date: | 2014-06-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Induced-fit mechanism in class i terpene cyclases. Angew.Chem.Int.Ed.Engl., 53, 2014
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4OQ1
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4OFQ
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![BU of 4ofq by Molmil](/molmil-images/mine/4ofq) | Structure of the C-terminal domain of the Streptococcus pyogenes antigen I/II-family protein AspA | Descriptor: | CALCIUM ION, Putative cell surface protein | Authors: | Hall, M, Nylander, A, Jenkinson, H.F, Persson, K. | Deposit date: | 2014-01-15 | Release date: | 2014-03-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the C-terminal domain of AspA (antigen I/II-family) protein from Streptococcus pyogenes. FEBS Open Bio, 4, 2014
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5XXZ
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4OHT
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![BU of 4oht by Molmil](/molmil-images/mine/4oht) | Crystal structure of succinic semialdehyde dehydrogenase from Streptococcus pyogenes in complex with NADP+ as the cofactor | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase | Authors: | Park, S.A, Jang, E.H, Chi, Y.M, Lee, K.S. | Deposit date: | 2014-01-18 | Release date: | 2014-12-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Kinetic and Structural Characterization for Cofactor Preference of Succinic Semialdehyde Dehydrogenase from Streptococcus pyogenes. Mol.Cells, 37, 2014
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3T44
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![BU of 3t44 by Molmil](/molmil-images/mine/3t44) | Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with indole glycerol phosphate (IGP) amd anthranilate | Descriptor: | 2-AMINOBENZOIC ACID, INDOLE-3-GLYCEROL PHOSPHATE, Indole-3-glycerol phosphate synthase | Authors: | Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2011-07-25 | Release date: | 2012-08-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published
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7BZJ
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![BU of 7bzj by Molmil](/molmil-images/mine/7bzj) | The Discovery of Benzhydrol-Oxaborole Hybrid Derivatives as Leucyl-tRNA Synthetase Inhibitors | Descriptor: | Leucine--tRNA ligase, [(1~{R},5~{R},6~{S},8~{R})-8-(6-aminopurin-9-yl)-4'-[(~{R})-oxidanyl-[4-(2-oxidanylidenepropylsulfanyl)phenyl]methyl]spiro[2,4,7-trioxa-3-boranuidabicyclo[3.3.0]octane-3,7'-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-triene]-6-yl]methoxy-tris(oxidanyl)phosphanium | Authors: | Liu, R.J, Li, H, Wang, E.D, Zhou, H. | Deposit date: | 2020-04-28 | Release date: | 2020-12-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of benzhydrol-oxaborole derivatives as Streptococcus pneumoniae leucyl-tRNA synthetase inhibitors. Bioorg.Med.Chem., 29, 2021
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5XYA
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![BU of 5xya by Molmil](/molmil-images/mine/5xya) | Crystal structure of a serine protease from Streptococcus species | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, CALCIUM ION, Chemokine protease C, ... | Authors: | Jobichen, C, Sivaraman, J. | Deposit date: | 2017-07-06 | Release date: | 2018-08-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of ScpC, a virulence protease fromStreptococcus pyogenes, reveals the functional domains and maturation mechanism. Biochem. J., 475, 2018
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6YA4
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6YA3
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![BU of 6ya3 by Molmil](/molmil-images/mine/6ya3) | |