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1SQ7
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BU of 1sq7 by Molmil
Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
Descriptor: Triosephosphate isomerase
Authors:Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
Deposit date:2004-03-18
Release date:2004-08-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
1SU5
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BU of 1su5 by Molmil
Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
Descriptor: 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
Deposit date:2004-03-26
Release date:2004-08-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
1SW7
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BU of 1sw7 by Molmil
Triosephosphate isomerase from Gallus gallus, loop 6 mutant K174N, T175S, A176S
Descriptor: 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase
Authors:Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
Deposit date:2004-03-30
Release date:2004-08-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
1SSD
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BU of 1ssd by Molmil
Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
Descriptor: SULFATE ION, Triosephosphate isomerase
Authors:Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
Deposit date:2004-03-24
Release date:2004-08-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
3PG1
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BU of 3pg1 by Molmil
MAP kinase LmaMPK10 from Leishmania major (1.95 angs resolution)
Descriptor: Mitogen-activated protein kinase, putative (Map kinase-like protein)
Authors:Horjales, S, Buschiazzo, A.
Deposit date:2010-10-29
Release date:2011-11-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms.
Structure, 20, 2012
1PGC
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BU of 1pgc by Molmil
NMR Solution Structure of an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link in a DNA Dodecamer Duplex
Descriptor: 5'-D(*CP*CP*TP*CP*AP*GP*GP*CP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*GP*CP*CP*TP*GP*AP*GP*G)-3', CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II)
Authors:Wu, Y, Pradhan, P, Havener, J, Chaney, S.G, Campbel, S.L.
Deposit date:2003-05-28
Release date:2004-07-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR solution structure of an oxaliplatin 1,2-d(GG) intrastrand cross-link in a DNA dodecamer duplex
J.Mol.Biol., 341, 2004
1TG5
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BU of 1tg5 by Molmil
Crystal structures of plant 4-hydroxyphenylpyruvate dioxygenases complexed with DAS645
Descriptor: 4-hydroxyphenylpyruvate dioxygenase, FE (II) ION, [1-TERT-BUTYL-3-(2,4-DICHLOROPHENYL)-5-HYDROXY-1H-PYRAZOL-4-YL][2-CHLORO-4-(METHYLSULFONYL)PHENYL]METHANONE
Authors:Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
Deposit date:2004-05-28
Release date:2004-08-17
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
3PH1
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BU of 3ph1 by Molmil
The Crystal Structure of a Pathogenic Protein from the Xanthomonas campestris Reveals a New Tetrameric PilZ Domain Self-Assembled via a Unusual Helical Bundle
Descriptor: ACETATE ION, Putative uncharacterized protein
Authors:Li, T.-N, Chin, K.-H, Yang, M.-D, Chou, S.-H.
Deposit date:2010-11-03
Release date:2011-04-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Crystal Structure of a Pathogenic Protein from the Xanthomonas campestris Reveals a New Tetrameric PilZ Domain Self-Assembled via a Unusual Helical Bundle
To be Published
6DU6
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BU of 6du6 by Molmil
Crystal structure of the pyruvate kinase (PK1) from the mosquito Aedes aegypti
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, Pyruvate kinase
Authors:Pizarro, J.C, Scaraffia, P.Y, Petchampai, N, Murillo-Solano, C.
Deposit date:2018-06-19
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.513 Å)
Cite:Distinctive regulatory properties of pyruvate kinase 1 from Aedes aegypti mosquitoes.
Insect Biochem. Mol. Biol., 104, 2018
6C5Y
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BU of 6c5y by Molmil
Crystal structure of thaumatin from microcrystals
Descriptor: Thaumatin-1
Authors:Guo, G, Fuchs, M, Shi, W, Skinner, J, Berman, E, Ogata, C.M, Hendrickson, W.A, McSweeney, S, Liu, Q.
Deposit date:2018-01-17
Release date:2018-05-30
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sample manipulation and data assembly for robust microcrystal synchrotron crystallography.
IUCrJ, 5, 2018
6DXS
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BU of 6dxs by Molmil
Crystal structure of the LigJ hydratase E284Q mutant substrate complex with (3Z)-2-keto-4-carboxy-3-hexenedioate
Descriptor: (2Z)-4-oxobut-2-ene-1,2,4-tricarboxylic acid, 4-oxalomesaconate hydratase, ZINC ION
Authors:Mabanglo, M.F, Raushel, F.M, Hogancamp, T.N.
Deposit date:2018-06-29
Release date:2018-09-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and Reaction Mechanism of the LigJ Hydratase: An Enzyme Critical for the Bacterial Degradation of Lignin in the Protocatechuate 4,5-Cleavage Pathway.
Biochemistry, 57, 2018
3R7X
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BU of 3r7x by Molmil
Crystal Structure Analysis of a Quinazolinedione sulfonamide bound to human GluR2: A Novel Class of Competitive AMPA Receptor Antagonists with Oral Activity
Descriptor: GLUTAMIC ACID, Glutamate receptor 2, N-[6-(1H-imidazol-1-yl)-7-nitro-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl]methanesulfonamide
Authors:Kallen, J.
Deposit date:2011-03-23
Release date:2011-05-18
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Quinazolinedione sulfonamides: A novel class of competitive AMPA receptor antagonists with oral activity.
Bioorg.Med.Chem.Lett., 21, 2011
1U7S
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BU of 1u7s by Molmil
Crystal structure of Native Sperm Whale myoglobin from low ionic strength enviroment (Form 1)
Descriptor: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Zhang, W, Phillips Jr, G.N.
Deposit date:2004-08-04
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Sampling of the native conformational ensemble of myoglobin via structures in different crystalline environments.
Proteins, 70, 2008
3NYB
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BU of 3nyb by Molmil
Structure and function of the polymerase core of TRAMP, a RNA surveillance complex
Descriptor: Poly(A) RNA polymerase protein 2, Protein AIR2, ZINC ION
Authors:Reinisch, K.M, Hamill, S.
Deposit date:2010-07-14
Release date:2010-08-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7007 Å)
Cite:Structure and function of the polymerase core of TRAMP, a RNA surveillance complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
3QF7
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BU of 3qf7 by Molmil
The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair
Descriptor: MAGNESIUM ION, Mre11, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Moeckel, C, Lammens, K.
Deposit date:2011-01-21
Release date:2011-04-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break Repair.
Cell(Cambridge,Mass.), 145, 2011
3QG5
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BU of 3qg5 by Molmil
The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair
Descriptor: GLYCEROL, Mre11, rad50
Authors:Lammens, K.
Deposit date:2011-01-24
Release date:2011-04-20
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break Repair.
Cell(Cambridge,Mass.), 145, 2011
5UHB
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BU of 5uhb by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with Rifampin
Descriptor: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2017-01-11
Release date:2017-04-12
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (4.29 Å)
Cite:Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
3OPZ
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BU of 3opz by Molmil
Crystal structure of trans-sialidase in complex with the Fab fragment of a neutralizing monoclonal IgG antibody
Descriptor: 1,4-DIETHYLENE DIOXIDE, SODIUM ION, Trans-sialidase, ...
Authors:Larrieux, N, Muia, R, Campetella, O, Buschiazzo, A.
Deposit date:2010-09-02
Release date:2011-11-09
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: structure/function studies towards the rational design of inhibitors.
Plos Pathog., 8, 2012
3NW6
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BU of 3nw6 by Molmil
Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11A)
Descriptor: Insulin-like growth factor 1 receptor, N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-{(2S)-1-[(6-fluoropyridin-3-yl)carbonyl]pyrrolidin-2-yl}pyrrolo[2,1-f][1,2,4]triazin-4-amine
Authors:Sack, J.S.
Deposit date:2010-07-09
Release date:2010-07-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase.
Bioorg.Med.Chem.Lett., 20, 2010
3NW7
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BU of 3nw7 by Molmil
Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (34)
Descriptor: Insulin-like growth factor 1 receptor, N-({4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}methyl)-6-fluoropyridine-3-carboxamide
Authors:Sack, J.S.
Deposit date:2010-07-09
Release date:2010-07-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase.
Bioorg.Med.Chem.Lett., 20, 2010
7JVK
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BU of 7jvk by Molmil
Structure of the M101A variant of the SidA ornithine hydroxylase with the FAD in the "out" conformation
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-08-21
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Flavin Dynamics in a Class B Monooxygenase.
Biochemistry, 59, 2020
5NFZ
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BU of 5nfz by Molmil
TUBULIN-MTC complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-methoxy-5-(2,3,4-trimethoxyphenyl)cyclohepta-2,4,6-trien-1-one, CALCIUM ION, ...
Authors:Field, J.J, Pera, B, Estevez Gallego, J, Calvo, E, Rodriguez-Salarichs, J, Saez-Calvo, G, Zuwerra, D, Jordi, M, Prota, A.E, Menchon, G, Miller, J.H, Altmann, K.-H, Diaz, J.F.
Deposit date:2017-03-16
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites.
J. Nat. Prod., 81, 2018
7JVL
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BU of 7jvl by Molmil
Structure of the M101A variant of the SidA ornithine hydroxylase complexed with NADP and the FAD in the "out" conformation
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-08-21
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Determinants of Flavin Dynamics in a Class B Monooxygenase.
Biochemistry, 59, 2020
2MFS
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BU of 2mfs by Molmil
Solution NMR structure of the cactus-derived antimicrobial peptide Ep-AMP1
Descriptor: Ep-AMP1
Authors:Rosengren, K, Goransson, U, Gunasekera, S, Aboye, T.L.
Deposit date:2013-10-22
Release date:2014-11-12
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:A cactus-derived toxin-like cystine knot Peptide with selective antimicrobial activity.
Chembiochem, 16, 2015
4RWX
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BU of 4rwx by Molmil
Crystal Structure of L. monocytogenes PstA
Descriptor: Lmo2692 protein
Authors:Choi, P.H, Tong, L.
Deposit date:2014-12-07
Release date:2014-12-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular basis for the recognition of cyclic-di-AMP by PstA, a PII -like signal transduction protein.
Microbiologyopen, 4, 2015

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数据于2025-07-09公开中

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