8I4C
| Cryo-EM structure of U46619-bound ABCC4 | Descriptor: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ATP-binding cassette sub-family C member 4 | Authors: | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | Deposit date: | 2023-01-19 | Release date: | 2023-05-24 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
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8IPT
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8IPS
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8IPR
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8IPQ
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8IZ8
| cryo EM structure of apo hMRP4 | Descriptor: | ATP-binding cassette sub-family C member 4 | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-04-06 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | cryo EM structure of apo hMRP4 To Be Published
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8IZ7
| cryo-EM structure of sulindac-bound hMRP4 | Descriptor: | ATP-binding cassette sub-family C member 4, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-04-06 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | cryo-EM structure of sulindac-bound hMRP4 To Be Published
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8IZP
| Multidrug resistance-associated protein 3 | Descriptor: | ATP-binding cassette sub-family C member 3 | Authors: | Yun, C.H, Gao, H.M. | Deposit date: | 2023-04-07 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | structure of multidrug resistance-associated protein 3 at 3.31 Angstroms To Be Published
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8IZR
| Multidrug resistance-associated protein 3 | Descriptor: | ATP-binding cassette sub-family C member 2 | Authors: | Yun, C.H, Gao, H.M. | Deposit date: | 2023-04-07 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | structure of multidrug resistance-associated protein 2 at 3.62 Angstroms resolution To Be Published
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8J3Z
| Cryo-EM structure of ATP-U46619-bound ABCC4 | Descriptor: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, ... | Authors: | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | Deposit date: | 2023-04-18 | Release date: | 2023-05-24 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
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8J3W
| Cryo-EM structure of aspirin-bound ABCC4 | Descriptor: | 2-(ACETYLOXY)BENZOIC ACID, ATP-binding cassette sub-family C member 4 | Authors: | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | Deposit date: | 2023-04-18 | Release date: | 2023-05-24 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
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8IZ9
| cryo-EM structure of PGE1-bound hMRP4 | Descriptor: | 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid, ATP-binding cassette sub-family C member 4 | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-04-06 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | cryo-EM structure of PGE1-bound hMRP4 To Be Published
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8IZA
| cryo-EM structure of ATP-bound hMRP4 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, MAGNESIUM ION | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-04-06 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | cryo-EM structure of ATP-bound hMRP4 To Be Published
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7S5X
| Human KATP channel in open conformation, focused on Kir and one SUR, position 1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | Authors: | Zhao, C, MacKinnon, R. | Deposit date: | 2021-09-12 | Release date: | 2021-12-01 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5V
| Human KATP channel in open conformation, focused on SUR | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | Authors: | Zhao, C, MacKinnon, R. | Deposit date: | 2021-09-12 | Release date: | 2021-12-01 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5Y
| Human KATP channel in open conformation, focused on Kir and one SUR, position 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | Authors: | Zhao, C, MacKinnon, R. | Deposit date: | 2021-09-12 | Release date: | 2021-12-01 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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7SGR
| Structure of hemolysin A secretion system HlyB/D complex | Descriptor: | Alpha-hemolysin translocation ATP-binding protein HlyB, Membrane fusion protein (MFP) family protein,Hemolysin secretion protein D, chromosomal, ... | Authors: | Zhao, H, Chen, J. | Deposit date: | 2021-10-07 | Release date: | 2022-09-14 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The hemolysin A secretion system is a multi-engine pump containing three ABC transporters. Cell, 185, 2022
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7SVR
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7SV7
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7SVD
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7T56
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7T54
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7T57
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7T55
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7SEL
| E. coli MsbA in complex with LPS and inhibitor G7090 (compound 3) | Descriptor: | (2E)-3-{7-[(1S)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1-methylnaphthalen-2-yl}prop-2-enoic acid, (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase | Authors: | Payandeh, J, Koth, C.M, Verma, V.A. | Deposit date: | 2021-09-30 | Release date: | 2022-03-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.978 Å) | Cite: | Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity. J.Med.Chem., 65, 2022
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