4ERK
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![BU of 4erk by Molmil](/molmil-images/mine/4erk) | THE COMPLEX STRUCTURE OF THE MAP KINASE ERK2/OLOMOUCINE | Descriptor: | EXTRACELLULAR REGULATED KINASE 2, OLOMOUCINE, SULFATE ION | Authors: | Wang, Z, Canagarajah, B, Boehm, J.C, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J. | Deposit date: | 1998-07-09 | Release date: | 1999-07-22 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of inhibitor selectivity in MAP kinases. Structure, 6, 1998
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5UMO
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![BU of 5umo by Molmil](/molmil-images/mine/5umo) | |
2ERK
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![BU of 2erk by Molmil](/molmil-images/mine/2erk) | PHOSPHORYLATED MAP KINASE ERK2 | Descriptor: | EXTRACELLULAR SIGNAL-REGULATED KINASE 2 | Authors: | Canagarajah, B.J, Goldsmith, E.J. | Deposit date: | 1997-06-26 | Release date: | 1998-07-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Activation mechanism of the MAP kinase ERK2 by dual phosphorylation. Cell(Cambridge,Mass.), 90, 1997
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2Z7L
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![BU of 2z7l by Molmil](/molmil-images/mine/2z7l) | |
2FYS
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![BU of 2fys by Molmil](/molmil-images/mine/2fys) | Crystal structure of Erk2 complex with KIM peptide derived from MKP3 | Descriptor: | Dual specificity protein phosphatase 6, Mitogen-activated protein kinase 1 | Authors: | Liu, S, Sun, J.P, Zhou, B, Zhang, Z.Y. | Deposit date: | 2006-02-08 | Release date: | 2006-04-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3 Proc.Natl.Acad.Sci.Usa, 103, 2006
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3C9W
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![BU of 3c9w by Molmil](/molmil-images/mine/3c9w) | Crystal Structure of ERK-2 with hypothemycin covalently bound | Descriptor: | (1aR,8S,13S,14S,15aR)-5,13,14-trihydroxy-3-methoxy-8-methyl-8,9,13,14,15,15a-hexahydro-6H-oxireno[k][2]benzoxacyclotetradecine-6,12(1aH)-dione, Mitogen-activated protein kinase 1 | Authors: | Rosenfeld, R.J. | Deposit date: | 2008-02-18 | Release date: | 2008-07-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular modeling and crystal structure of ERK2-hypothemycin complexes J.Struct.Biol., 164, 2008
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4S34
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![BU of 4s34 by Molmil](/molmil-images/mine/4s34) | ERK2 (I84A) in complex with AMP-PNP | Descriptor: | MAGNESIUM ION, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Livnah, O, Karamansha, Y, Tzarum, N. | Deposit date: | 2015-01-26 | Release date: | 2016-01-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Multiple mechanisms render Erk proteins MEK-independent To be Published
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6OPK
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![BU of 6opk by Molmil](/molmil-images/mine/6opk) | Phosphorylated ERK2 with Vertex-11e | Descriptor: | 4-{2-[(2-chloro-4-fluorophenyl)amino]-5-methylpyrimidin-4-yl}-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide, Mitogen-activated protein kinase 1 | Authors: | Vigers, G.P, Rudolph, J. | Deposit date: | 2019-04-25 | Release date: | 2019-07-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2. Proc.Natl.Acad.Sci.USA, 116, 2019
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4XRL
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![BU of 4xrl by Molmil](/molmil-images/mine/4xrl) | Crystal structure at room temperature of Erk2 in complex with an inhibitor | Descriptor: | 1H-pyrrolo[2,3-b]pyridine-3-carbonitrile, Mitogen-activated protein kinase 1, SULFATE ION | Authors: | Gelin, M, Allemand, F, Labesse, G, Guichou, J.F. | Deposit date: | 2015-01-21 | Release date: | 2016-03-23 | Last modified: | 2016-03-30 | Method: | X-RAY DIFFRACTION (2.554 Å) | Cite: | Combining 'dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography. Acta Crystallogr.,Sect.D, 71, 2015
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3ZUV
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![BU of 3zuv by Molmil](/molmil-images/mine/3zuv) | |
1GOL
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![BU of 1gol by Molmil](/molmil-images/mine/1gol) | |