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PDB: 1196 results

1X7Q
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Crystal structure of HLA-A*1101 with sars nucleocapsid peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Blicher, T, Kastrup, J.S, Buus, S, Gajhede, M.
Deposit date:2004-08-16
Release date:2005-08-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide.
Acta Crystallogr.,Sect.D, 61, 2005
6PYV
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BU of 6pyv by Molmil
Crystal Structure of HLA-B*2703-P47G in complex with LRN, a self-peptide
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-2703 alpha chain, ...
Authors:Gras, S.
Deposit date:2019-07-31
Release date:2019-11-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
J.Biol.Chem., 294, 2019
4RMQ
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Crystal structure of the D59N Beta-2 Microglobulin mutant
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.461 Å)
Cite:Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
5C0F
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BU of 5c0f by Molmil
HLA-A02 carrying RQWGPDPAAV
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETIC ACID, ...
Authors:Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.463 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
4RMV
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BU of 4rmv by Molmil
Crystal structure of the D76H Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.463 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
4U6Y
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BU of 4u6y by Molmil
Crystal Structure of HLA-A*0201 in complex with FLNDK, a 15 mer self-peptide
Descriptor: Beta-2-microglobulin, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Gras, S, Chabrol, E, Rossjohn, J.
Deposit date:2014-07-30
Release date:2014-12-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.467 Å)
Cite:Naturally Processed Non-canonical HLA-A*02:01 Presented Peptides.
J.Biol.Chem., 290, 2015
1OGT
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BU of 1ogt by Molmil
CRYSTAL STRUCTURE OF HLA-B*2705 COMPLEXED WITH THE VASOACTIVE INTESTINAL PEPTIDE TYPE 1 RECEPTOR (VIPR) PEPTIDE (RESIDUES 400-408)
Descriptor: BETA-2-MICROGLOBULIN, GLYCEROL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Hulsmeyer, M, Fiorillo, M.T, Bettosini, F, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
Deposit date:2003-05-13
Release date:2004-01-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Dual, HLA-B27 subtype-dependent conformation of a self-peptide.
J. Exp. Med., 199, 2004
1XH3
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Conformational Restraints and Flexibility of 14-Meric Peptides in Complex with HLA-B*3501
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Probst-Kepper, M, Hecht, H.J, Herrmann, H, Janke, V, Ocklenburg, F, Klempnauer, J, van den Eynde, B.J, Weiss, S.
Deposit date:2004-09-17
Release date:2004-11-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501.
J.Immunol., 173, 2004
6P2F
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BU of 6p2f by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
Authors:Li, L, Batliwala, M, Bouvier, M.
Deposit date:2019-05-21
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
5CFH
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BU of 5cfh by Molmil
human beta-2 microglobulin double mutant W60G-Y63W
Descriptor: Beta-2-microglobulin
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-08
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
8E8I
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Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove
Descriptor: Beta-2-microglobulin, MHC class I antigen, PHE-VAL-LYS-LYS-LYS-TYR-CYS-LEU
Authors:Li, L, Bouvier, M.
Deposit date:2022-08-25
Release date:2023-07-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing.
Nat Commun, 14, 2023
5C0E
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HLA-A02 carrying YLGGPDFPTI
Descriptor: 1,2-ETHANEDIOL, BROMIDE ION, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
7WKJ
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BU of 7wkj by Molmil
A COVID-19 T-cell response detection method based on a newly identified human CD8+ T cell epitope from SARS-CoV-2-Hubei Province, 2021.
Descriptor: Beta-2-microglobulin, LYS-THR-PHE-PRO-PRO-THR-GLU-PRO-LYS, MHC class I antigen
Authors:Zhang, J, Lu, D, Li, M, Liu, M.S, Yao, S.J, Zhan, J.B, Liu, J, Gao, G.F.
Deposit date:2022-01-10
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A COVID-19 T-Cell Response Detection Method Based on a Newly Identified Human CD8 + T Cell Epitope from SARS-CoV-2 - Hubei Province, China, 2021.
China CDC Wkly, 4, 2022
6AT5
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BU of 6at5 by Molmil
Crystal structure of HLA-B*07:02 in complex with an NY-ESO-1 peptide
Descriptor: Beta-2-microglobulin, Cancer/testis antigen 1 peptide, HLA class I histocompatibility antigen, ...
Authors:Gully, B.S, Rossjohn, J.
Deposit date:2017-08-27
Release date:2018-02-28
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
Nat Commun, 9, 2018
5IEH
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BU of 5ieh by Molmil
Structure of HLA-B*40:02 in complex with the phosphorylated endogenous peptide REF(p)SKEPEL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Alpizar, A, Marcilla, M, Santiago, C.
Deposit date:2016-02-25
Release date:2016-12-07
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of HLA-B*40:02 in complex with the phosphorilated endogenous peptide REFpSKEPEL
To Be Published
6O4Z
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BU of 6o4z by Molmil
Structure of HLA-A2:01 with peptide MM92
Descriptor: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
Authors:Ying, G, Bitra, A, Zajonc, D.M.
Deposit date:2019-03-01
Release date:2020-01-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Front Immunol, 10, 2019
6WZY
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BU of 6wzy by Molmil
Structure of DbNA(10) peptides bound to H-2Db MHC-I
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Farenc, C, Rossjohn, J.
Deposit date:2020-05-14
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Overlapping Peptides Elicit Distinct CD8 + T Cell Responses following Influenza A Virus Infection.
J Immunol., 205, 2020
7M8T
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BU of 7m8t by Molmil
Crystal Structure of HLA-A*11:01 in complex with NSASFSTFK, an 9-mer epitope from SARS-CoV-2 spike (S370-378)
Descriptor: Beta-2-microglobulin, CALCIUM ION, CHLORIDE ION, ...
Authors:Gras, S, Nguyen, A.T, Szeto, C.
Deposit date:2021-03-30
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:SARS-CoV-2 Spike-Derived Peptides Presented by HLA Molecules
Biophysica, 1, 2021
2HJL
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BU of 2hjl by Molmil
Crystal Structure of HLA-B5703 and HIV-1 peptide
Descriptor: Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen B-57
Authors:Gillespie, G.M.A, Stewart-Jones, G, Rengasamy, J, Beattie, T, Bwayo, J.J, Plummer, F.A.
Deposit date:2006-06-30
Release date:2006-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection.
J.Immunol., 177, 2006
5CSG
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BU of 5csg by Molmil
The crystal structure of beta2-microglobulin R97Q mutant
Descriptor: ACETATE ION, Beta-2-microglobulin
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
7YG3
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BU of 7yg3 by Molmil
Crystal structure of HLA-B*13:01
Descriptor: ARG-GLN-ASP-ILE-LEU-ASP-LEU-TRP-ILE, Beta-2-microglobulin, MHC class I antigen
Authors:Wang, H.S, Ouyang, S.Y.
Deposit date:2022-07-11
Release date:2023-07-26
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity.
J.Biomed.Sci., 29, 2022
6Q3K
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BU of 6q3k by Molmil
Engineered Human HLA_A2 MHC Class I molecule in complex with NV9 peptide
Descriptor: ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, COBALT (II) ION, ...
Authors:Meijers, R, Anjanappa, R, Springer, S, Garcia-Alai, M.
Deposit date:2018-12-04
Release date:2019-07-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Engineered Human HLA_A2MHC Class I molecule in complex with NV9 peptide
Sci Immunol, 2019
5DDH
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BU of 5ddh by Molmil
Structure of HLA-A2:01 with the 12-mer peptide F12K
Descriptor: 12-mer peptide F12K, Beta-2-microglobulin, GLYCEROL, ...
Authors:Remesh, S.G, Zajonc, D.
Deposit date:2015-08-24
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove.
Elife, 5, 2016
2FYY
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BU of 2fyy by Molmil
The role of T cell receptor alpha genes in directing human MHC restriction
Descriptor: 11-mer peptide from Epstein-Barr nuclear antigen 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Miles, J.J, Borg, N.A.
Deposit date:2006-02-08
Release date:2006-12-26
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope.
J Immunol., 177, 2006
4JQV
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BU of 4jqv by Molmil
HLA-B*18:01 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 173-180)
Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Theodossis, A, Welland, A, Gras, S, Rossjohn, J.
Deposit date:2013-03-20
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:HLA Peptide Length Preferences Control CD8+ T Cell Responses.
J.Immunol., 191, 2013

226262

数据于2024-10-16公开中

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