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PDB: 226 results
7QL0
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BU of 7ql0 by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgSO4 and NaCl (15c)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKI
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BU of 7qki by Molmil
In vitro assembled 297-408 S396D S400D T403D S404D tau filaments (42a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QJY
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BU of 7qjy by Molmil
In vitro assembled 266/297 - 391 tau filaments with LiCl (9a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8Q9D
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BU of 8q9d by Molmil
Tau - CTE-MIA15 (tau intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-20
Release date:2023-09-20
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q8Z
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BU of 8q8z by Molmil
Tau - CTE-MIA7 (tau intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-19
Release date:2023-09-20
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QKX
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BU of 7qkx by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgSO4 and NaCl (15b)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8BGS
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BU of 8bgs by Molmil
Tau Paired Helical Filament from Extracellular Vesicles from Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Behr, T.S, Ryskeldi-Falcon, B.
Deposit date:2022-10-28
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Biorxiv, 2023
7QKH
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BU of 7qkh by Molmil
In vitro assembled 258-391 tau filaments with sodium azide, (41a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-03-02
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8ZWM
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BU of 8zwm by Molmil
Heparin bound Tau fibril polymorph 4
Descriptor: Isoform Tau-F of Microtubule-associated protein tau
Authors:Tao, Y.Q, Liu, C, Li, D.
Deposit date:2024-06-13
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Heparin bound Tau fibril polymorph 4
To Be Published
6GX5
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BU of 6gx5 by Molmil
Narrow Pick Filament from Pick's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Falcon, B, Zhang, W, Murzin, A.G, Murshudov, G, Garringer, H.J, Vidal, R, Crowther, R.A, Ghetti, B, Scheres, S.H.W, Goedert, M.
Deposit date:2018-06-26
Release date:2018-09-12
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature, 561, 2018
8OTC
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BU of 8otc by Molmil
CTE typeII tau filament from Guam ALS/PDC
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8Q9K
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BU of 8q9k by Molmil
Tau - CTE-LIA13 (tau intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-20
Release date:2023-09-06
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QL4
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BU of 7ql4 by Molmil
in vitro assembled tau filaments with structures like Paired Helical Filaments from Alzheimer's Disease
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
6HRE
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BU of 6hre by Molmil
Paired helical filament from sporadic Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
Deposit date:2018-09-26
Release date:2018-10-10
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6TJO
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BU of 6tjo by Molmil
Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
Deposit date:2019-11-26
Release date:2020-02-05
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
9BBM
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BU of 9bbm by Molmil
PHF filament generated from 4E-Tau(297-407) under neutral Mg2+ condition
Descriptor: Isoform Tau-F of Microtubule-associated protein tau
Authors:Duan, P, El Mammeri, N.
Deposit date:2024-04-06
Release date:2024-05-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Milligram-scale assembly and NMR fingerprint of tau fibrils adopting the Alzheimer's disease fold.
J.Biol.Chem., 300, 2024
6CVJ
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BU of 6cvj by Molmil
Model of synthetic tau (four tandem repeats of first repeat sequence) bound to the microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nogales, E, Kellogg, E.H.
Deposit date:2018-03-28
Release date:2018-05-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Near-atomic model of microtubule-tau interactions.
Science, 360, 2018
8QCP
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BU of 8qcp by Molmil
Tau - AD-LIA8 (tau intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-28
Release date:2023-09-06
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QKV
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BU of 7qkv by Molmil
In vitro assembled tau filaments with MgSO4 and NaCl (15a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8Q7M
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BU of 8q7m by Molmil
Tau - AD-MIA7 (tau intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-16
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QKJ
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BU of 7qkj by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgCl2 and NaCl (14b)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-03-23
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8BGV
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BU of 8bgv by Molmil
Tau Paired Helical Filament from Cellular Fraction of Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Behr, T.S, Ryskeldi-Falcon, B.
Deposit date:2022-10-28
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Biorxiv, 2023
8Q7P
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BU of 8q7p by Molmil
Tau - AD-MIA8 (intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-16
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QJV
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BU of 7qjv by Molmil
In vitro assembled tau filaments into Quadruple Helical Filaments type 1 (2c)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7P6D
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BU of 7p6d by Molmil
Argyrophilic grain disease type 1 tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021

222415

数据于2024-07-10公开中

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