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PDB: 284 results

8PH9
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BU of 8ph9 by Molmil
E. coli RNA polymerase paused at ops site (non-complementary scaffold)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
6ZTP
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BU of 6ztp by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 6
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZU1
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BU of 6zu1 by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 2
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-21
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTO
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BU of 6zto by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 1
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-23
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6PST
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BU of 6pst by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
7YPA
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BU of 7ypa by Molmil
Cryo-EM structure of Escherichia coli hairpin-nucleation complex of transcription termination (TTC-hairpin)
Descriptor: DNA (31-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:You, L.L, Zhang, Y.
Deposit date:2022-08-03
Release date:2022-11-16
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Structural basis for intrinsic transcription termination.
Nature, 613, 2023
8TOM
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BU of 8tom by Molmil
Escherichia coli RNA polymerase closed complex intermediate at the lambda PR promoter
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Darst, S.A, Saecker, R.M, Mueller, A.U.
Deposit date:2023-08-03
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy
Nat.Struct.Mol.Biol., 2024
8PEN
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BU of 8pen by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-14
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PFG
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BU of 8pfg by Molmil
autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex), not fully complementary scaffold
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-15
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PHK
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BU of 8phk by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-20
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8URY
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BU of 8ury by Molmil
Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 30 nt long spacer, and fMet-tRNA in E-site and P-site of the ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ...
Authors:Molodtsov, V, Wang, C, Ebright, R.H.
Deposit date:2023-10-27
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of RfaH-mediated transcription-translation coupling
Nat.Struct.Mol.Biol., 2024
8IGR
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BU of 8igr by Molmil
Cryo-EM structure of CII-dependent transcription activation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y.
Deposit date:2023-02-21
Release date:2023-05-17
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of lambda CII-dependent transcription activation.
Structure, 31, 2023
7UWH
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BU of 7uwh by Molmil
CryoEM Structure of E. coli Transcription-Coupled Ribonucleotide Excision Repair (TC-RER) complex bound to ribonucleotide substrate
Descriptor: DNA (59-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Grower, M, Bharati, B, Proshkin, S, Epshtein, V, Svetlov, V, Nudler, E, Shamovsky, I.
Deposit date:2022-05-03
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:RNA polymerase drives ribonucleotide excision DNA repair in E. coli.
Cell, 186, 2023
6X7K
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BU of 6x7k by Molmil
Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Ebright, R.H, Wang, C, Su, M.
Deposit date:2020-05-30
Release date:2020-09-02
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
7SZJ
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BU of 7szj by Molmil
Cryo-EM structure of Rifamycin bound to E. coli RNAP and rrnBP1 promoter complex
Descriptor: DNA (49-MER), DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2021-11-28
Release date:2022-07-13
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis.
Acs Infect Dis., 8, 2022
7UBM
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BU of 7ubm by Molmil
Transcription antitermination complex: "pre-engaged" Qlambda-loading complex
Descriptor: Antitermination protein Q, DNA (52-MER), DNA (53-MER), ...
Authors:Yin, Z, Ebright, R.H.
Deposit date:2022-03-15
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MKO
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BU of 7mko by Molmil
Escherichia coli RNA polymerase elongation complex
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Qayyum, M.Z, Murakami, K.S.
Deposit date:2021-04-26
Release date:2021-06-02
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli.
J.Biol.Chem., 297, 2021
7XUE
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BU of 7xue by Molmil
Cryo-EM structure of HK022 putRNA-associated E.coli RNA polymerase elongation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Hwang, S.H, Kang, J.Y.
Deposit date:2022-05-18
Release date:2022-08-10
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA.
Nat Commun, 13, 2022
6WMU
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BU of 6wmu by Molmil
E. coli RNAPs70-SspA-gadA DNA complex
Descriptor: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
Authors:Travis, B.A, Brennan, R.G, Schumacher, M.A.
Deposit date:2020-04-21
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
8EG7
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BU of 8eg7 by Molmil
Cryo-EM structure of pre-consensus elemental paused elongation complex
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
Deposit date:2022-09-11
Release date:2023-03-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
7MKD
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BU of 7mkd by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1)
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Saecker, R.M, Darst, S.A, Chen, J.
Deposit date:2021-04-23
Release date:2021-09-29
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
6X6T
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BU of 6x6t by Molmil
Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B1 (TTC-B1) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Ebright, R.H, Wang, C, Su, M.
Deposit date:2020-05-29
Release date:2020-09-02
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6XLM
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BU of 6xlm by Molmil
Cryo-EM structure of E.coli RNAP-DNA elongation complex 1 (RDe1) in EcmrR-dependent transcription
Descriptor: 9-nt RNA transcript, CHAPSO, DNA-directed RNA polymerase subunit alpha, ...
Authors:Yang, Y, Liu, C, Liu, B.
Deposit date:2020-06-28
Release date:2021-04-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
8PIL
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BU of 8pil by Molmil
E. coli transcription complex paused at ops site and bound to RfaH and NusA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-22
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8UQL
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BU of 8uql by Molmil
Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in loaded state, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Ebright, R.H.
Deposit date:2023-10-24
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024

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数据于2024-07-10公开中

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