3IDX
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![BU of 3idx by Molmil](/molmil-images/mine/3idx) | Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C222 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fab b13 heavy chain, ... | Authors: | Chen, L, Kwon, Y.D, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z.Y, Zhang, M.Y, Arthos, J, Burton, D.R, Dimitrov, D.S, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D. | Deposit date: | 2009-07-22 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science, 326, 2009
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5YB4
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![BU of 5yb4 by Molmil](/molmil-images/mine/5yb4) | Crystal structure of HP23LN36KR | Descriptor: | HP23L, N36KR | Authors: | Zhang, X, Wang, X, He, Y. | Deposit date: | 2017-09-03 | Release date: | 2018-02-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket Front Cell Infect Microbiol, 8, 2018
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1GC1
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![BU of 1gc1 by Molmil](/molmil-images/mine/1gc1) | HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, CD4, ... | Authors: | Kwong, P.D, Wyatt, R, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A. | Deposit date: | 1998-06-15 | Release date: | 1998-07-08 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature, 393, 1998
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4JPJ
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![BU of 4jpj by Molmil](/molmil-images/mine/4jpj) | Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 | Authors: | Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. | Deposit date: | 2013-03-19 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Rational HIV immunogen design to target specific germline B cell receptors. Science, 340, 2013
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7RI1
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![BU of 7ri1 by Molmil](/molmil-images/mine/7ri1) | |
6WWC
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![BU of 6wwc by Molmil](/molmil-images/mine/6wwc) | |
5CMZ
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![BU of 5cmz by Molmil](/molmil-images/mine/5cmz) | Artificial HIV fusion inhibitor AP3 fused to the C-terminus of gp41 NHR | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Artificial HIV entry inhibitor AP3, ... | Authors: | Zhu, Y, Ye, S, Zhang, R. | Deposit date: | 2015-07-17 | Release date: | 2015-09-16 | Method: | X-RAY DIFFRACTION (2.574 Å) | Cite: | Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy. Sci Rep, 5, 2015
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1ENV
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![BU of 1env by Molmil](/molmil-images/mine/1env) | ATOMIC STRUCTURE OF THE ECTODOMAIN FROM HIV-1 GP41 | Descriptor: | HIV-1 ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO TWO FRAGMENTS OF GP41 | Authors: | Weissenhorn, W, Dessen, A, Harrison, S.C, Skehel, J.J, Wiley, D.C. | Deposit date: | 1997-06-27 | Release date: | 1997-11-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Atomic structure of the ectodomain from HIV-1 gp41. Nature, 387, 1997
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6O42
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![BU of 6o42 by Molmil](/molmil-images/mine/6o42) | |
5WET
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![BU of 5wet by Molmil](/molmil-images/mine/5wet) | Crystal Structure of H2-Dd with disulfide-linked 6mer peptide | Descriptor: | Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ... | Authors: | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | Deposit date: | 2017-07-10 | Release date: | 2017-10-18 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
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8TQ8
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![BU of 8tq8 by Molmil](/molmil-images/mine/8tq8) | Crystal structure of Fab.34.5.8 in complex with MHC-I (H2-Dd) | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Fab.34.5.8 Heavy chain, ... | Authors: | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | Deposit date: | 2023-08-06 | Release date: | 2024-03-20 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction. J Immunol., 212, 2024
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1DF5
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![BU of 1df5 by Molmil](/molmil-images/mine/1df5) | |
4YDV
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![BU of 4ydv by Molmil](/molmil-images/mine/4ydv) | STRUCTURE OF THE ANTIBODY 7B2 THAT CAPTURES HIV-1 VIRIONS | Descriptor: | HIV ANTIBODY 7B2 HEAVY CHAIN,IgG H chain, HIV ANTIBODY 7B2 LIGHT CHAIN,Ig kappa chain C region, HIV GP41 PEPTIDE GP41(596-606) | Authors: | Nicely, N.I, Pemble IV, C.W. | Deposit date: | 2015-02-23 | Release date: | 2015-08-12 | Last modified: | 2021-03-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques. Plos Pathog., 11, 2015
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5WES
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![BU of 5wes by Molmil](/molmil-images/mine/5wes) | Crystal Structure H2-Dd with disulfide-linked 5mer peptide | Descriptor: | Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ... | Authors: | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | Deposit date: | 2017-07-10 | Release date: | 2017-10-18 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.706 Å) | Cite: | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
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6NCP
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![BU of 6ncp by Molmil](/molmil-images/mine/6ncp) | Crystal structure of HIV-1 broadly neutralizing antibody ACS202 | Descriptor: | ACS202 Fab heavy chain, ACS202 Fab light chain, GLYCINE, ... | Authors: | Yuan, M, Wilson, I.A. | Deposit date: | 2018-12-11 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019
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7R74
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![BU of 7r74 by Molmil](/molmil-images/mine/7r74) | |
8TQ7
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![BU of 8tq7 by Molmil](/molmil-images/mine/8tq7) | Crystal structure of Fab.34.2.12 in complex with MHC-I (H2-Dd) | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Fab 34.2.12 Light Chain, ... | Authors: | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | Deposit date: | 2023-08-06 | Release date: | 2024-03-20 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction. J Immunol., 212, 2024
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5H0N
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![BU of 5h0n by Molmil](/molmil-images/mine/5h0n) | |
5BN0
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![BU of 5bn0 by Molmil](/molmil-images/mine/5bn0) | A new HIV fusion peptide inhibitor | Descriptor: | Envelope glycoprotein, Envelope glycoprotein gp160 | Authors: | Xue, Y. | Deposit date: | 2015-05-25 | Release date: | 2016-05-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A new HIV fusion peptide inhibitor To Be Published
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8TQ9
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![BU of 8tq9 by Molmil](/molmil-images/mine/8tq9) | Crystal structure of Fab.S19.8 in complex with MHC-I (H2-Dd) | Descriptor: | Beta-2-microglobulin, Fab.S19.8 Heavy Chain, Fab.S19.8 Light Chain, ... | Authors: | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | Deposit date: | 2023-08-06 | Release date: | 2024-03-20 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction. J Immunol., 212, 2024
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5HM1
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![BU of 5hm1 by Molmil](/molmil-images/mine/5hm1) | |
6MQS
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![BU of 6mqs by Molmil](/molmil-images/mine/6mqs) | |
1FAV
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![BU of 1fav by Molmil](/molmil-images/mine/1fav) | THE STRUCTURE OF AN HIV-1 SPECIFIC CELL ENTRY INHIBITOR IN COMPLEX WITH THE HIV-1 GP41 TRIMERIC CORE | Descriptor: | HIV-1 ENVELOPE PROTEIN CHIMERA, PROTEIN (TRANSMEMBRANE GLYCOPROTEIN) | Authors: | Zhou, G, Ferrer, M, Chopra, R, Strassmaier, T, Weissenhorn, W, Skehel, J.J, Oprian, D, Schreiber, S.L, Harrison, S.C, Wiley, D.C. | Deposit date: | 2000-07-13 | Release date: | 2000-08-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorg.Med.Chem., 8, 2000
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6SND
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![BU of 6snd by Molmil](/molmil-images/mine/6snd) | crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide | Descriptor: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. | Deposit date: | 2019-08-23 | Release date: | 2019-11-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01. Cell Host Microbe, 26, 2019
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5WDF
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![BU of 5wdf by Molmil](/molmil-images/mine/5wdf) | |