6PXR
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![BU of 6pxr by Molmil](/molmil-images/mine/6pxr) | Anti-TAU BIIB092 FAB with TAU peptide | Descriptor: | Microtubule-associated protein tau, gosuranemab Fab, heavy chain, ... | Authors: | Arndt, J.W, Quan, C. | Deposit date: | 2019-07-26 | Release date: | 2020-07-29 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.556 Å) | Cite: | Characterization of tau binding by gosuranemab. Neurobiol.Dis., 146, 2020
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3BKJ
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![BU of 3bkj by Molmil](/molmil-images/mine/3bkj) | Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16) | Descriptor: | Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | Deposit date: | 2007-12-06 | Release date: | 2008-04-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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3BAE
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![BU of 3bae by Molmil](/molmil-images/mine/3bae) | Crystal structure of Fab WO2 bound to the N terminal domain of Amyloid beta peptide (1-28) | Descriptor: | Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Parker, M.W. | Deposit date: | 2007-11-07 | Release date: | 2008-04-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.593 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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4TQE
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![BU of 4tqe by Molmil](/molmil-images/mine/4tqe) | |
4TPR
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![BU of 4tpr by Molmil](/molmil-images/mine/4tpr) | Structure of Tau5 antibody Fab fragment | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol, CHLORIDE ION, ... | Authors: | Cehlar, O, Skrabana, R, Novak, M. | Deposit date: | 2014-06-09 | Release date: | 2015-07-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of Tau5 antibody Fab fragment To Be Published
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3BKM
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![BU of 3bkm by Molmil](/molmil-images/mine/3bkm) | Structure of anti-amyloid-beta Fab WO2 (Form A, P212121) | Descriptor: | SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa, ... | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | Deposit date: | 2007-12-07 | Release date: | 2008-04-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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3V4U
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![BU of 3v4u by Molmil](/molmil-images/mine/3v4u) | Structure of a monoclonal antibody complexed with its MHC-I antigen | Descriptor: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | Authors: | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | Deposit date: | 2011-12-15 | Release date: | 2012-07-25 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3UO1
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![BU of 3uo1 by Molmil](/molmil-images/mine/3uo1) | Structure of a monoclonal antibody complexed with its MHC-I antigen | Descriptor: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | Authors: | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | Deposit date: | 2011-11-16 | Release date: | 2012-07-25 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (1.641 Å) | Cite: | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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2IPU
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![BU of 2ipu by Molmil](/molmil-images/mine/2ipu) | |
3V52
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![BU of 3v52 by Molmil](/molmil-images/mine/3v52) | Structure of a monoclonal antibody complexed with its MHC-I antigen | Descriptor: | 1,2-ETHANEDIOL, ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, ... | Authors: | Mage, M.G, Dolan, M.A, Wang, R, Boyd, L.F, Revilleza, M.J, Robinson, H, Natarajan, K, Myers, N.B, Hansen, T.H, Margulies, D.H. | Deposit date: | 2011-12-15 | Release date: | 2012-07-25 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (1.697 Å) | Cite: | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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2DQU
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![BU of 2dqu by Molmil](/molmil-images/mine/2dqu) | Crystal form II: high resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog | Descriptor: | IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER | Authors: | Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I. | Deposit date: | 2006-05-30 | Release date: | 2006-06-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis J.Mol.Biol., 369, 2007
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3UYR
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![BU of 3uyr by Molmil](/molmil-images/mine/3uyr) | Structure of a monoclonal antibody complexed with its MHC-I antigen | Descriptor: | 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ... | Authors: | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | Deposit date: | 2011-12-06 | Release date: | 2012-07-25 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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1ZEA
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![BU of 1zea by Molmil](/molmil-images/mine/1zea) | Structure of the anti-cholera toxin antibody Fab fragment TE33 in complex with a D-peptide | Descriptor: | CITRIC ACID, monoclonal anti-cholera toxin IGG1 KAPPA antibody, H chain, ... | Authors: | Scheerer, P, Krauss, N, Wessner, H, Scholz, C, Otte, L, Seifert, M, Kramer, A, Schneider-Mergener, J, Hoehne, W. | Deposit date: | 2005-04-18 | Release date: | 2006-04-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure of an anti-cholera toxin antibody Fab in complex with an epitope-derived D-peptide: a case of polyspecific recognition. J.Mol.Recognit., 20, 2007
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1PZ5
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![BU of 1pz5 by Molmil](/molmil-images/mine/1pz5) | Structural basis of peptide-carbohydrate mimicry in an antibody combining site | Descriptor: | Heavy chain of Fab (SYA/J6), Light chain of Fab (SYA/J6), Octapeptide (MDWNMHAA) | Authors: | Vyas, N.K, Vyas, M.N, Chervenak, M.C, Bundle, D.R, Pinto, B.M, Quiocho, F.A. | Deposit date: | 2003-07-09 | Release date: | 2003-11-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of peptide-carbohydrate mimicry in an antibody combining site. Proc.Natl.Acad.Sci.USA, 100, 2003
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2DQT
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![BU of 2dqt by Molmil](/molmil-images/mine/2dqt) | High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog | Descriptor: | IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER | Authors: | Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I. | Deposit date: | 2006-05-30 | Release date: | 2006-06-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis J.Mol.Biol., 369, 2007
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1T2Q
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![BU of 1t2q by Molmil](/molmil-images/mine/1t2q) | The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab NNA7 Heavy Chain, Fab NNA7 Light Chain, ... | Authors: | Xie, K, Song, S.C, Spitalnik, S.L, Wedekind, J.E. | Deposit date: | 2004-04-22 | Release date: | 2005-06-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal Structure and Mutational Analysis of an Antibody that Recognizes an N-type Blood Group Antigen To be Published
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1F3D
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![BU of 1f3d by Molmil](/molmil-images/mine/1f3d) | CATALYTIC ANTIBODY 4B2 IN COMPLEX WITH ITS AMIDINIUM HAPTEN. | Descriptor: | 2-(4-AMINOBENZYLAMINO)-3,4,5,6-TETRAHYDROPYRIDINIUM, CATALYTIC ANTIBODY 4B2, SULFATE ION | Authors: | Golinelli-Pimpaneau, B, Goncalves, O, Dintinger, T, Blanchard, D, Knossow, M, Tellier, C. | Deposit date: | 2000-06-02 | Release date: | 2000-09-13 | Last modified: | 2012-07-04 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural evidence for a programmed general base in the active site of a catalytic antibody. Proc.Natl.Acad.Sci.USA, 97, 2000
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2OK0
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![BU of 2ok0 by Molmil](/molmil-images/mine/2ok0) | Fab ED10-DNA complex | Descriptor: | 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain | Authors: | Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G. | Deposit date: | 2007-01-15 | Release date: | 2007-06-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Specific recognition of a DNA immunogen by its elicited antibody J.Mol.Biol., 370, 2007
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3BKC
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![BU of 3bkc by Molmil](/molmil-images/mine/3bkc) | Crystal structure of anti-amyloid beta FAB WO2 (P21, FormB) | Descriptor: | SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | Deposit date: | 2007-12-06 | Release date: | 2008-04-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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4P3D
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![BU of 4p3d by Molmil](/molmil-images/mine/4p3d) | MT1-MMP:Fab complex (Form II) | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Rozenberg, H, Udi, Y, Sagi, I. | Deposit date: | 2014-03-07 | Release date: | 2014-12-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody. Structure, 23, 2015
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3EYS
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![BU of 3eys by Molmil](/molmil-images/mine/3eys) | |
2IQA
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![BU of 2iqa by Molmil](/molmil-images/mine/2iqa) | PFA2 FAB fragment, monoclinic apo form | Descriptor: | ACETAMIDE, CHLORIDE ION, GLYCEROL, ... | Authors: | Gardberg, A.S, Dealwis, C. | Deposit date: | 2006-10-13 | Release date: | 2007-10-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for passive immunotherapy of Alzheimer's disease Proc.Natl.Acad.Sci.Usa, 104, 2007
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1LO0
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![BU of 1lo0 by Molmil](/molmil-images/mine/1lo0) | Catalytic Retro-Diels-Alderase Transition State Analogue Complex | Descriptor: | 3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACID, If kappa light chain, Ig gamma 2a heavy chain | Authors: | Hugot, M, Reymond, J.L, Baumann, U. | Deposit date: | 2002-05-05 | Release date: | 2002-06-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue. Proc.Natl.Acad.Sci.USA, 99, 2002
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2IPT
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![BU of 2ipt by Molmil](/molmil-images/mine/2ipt) | PFA1 Fab Fragment | Descriptor: | ACETAMIDE, IgG2a Fab fragment Heavy Chain, IgG2a Fab fragment Light Chain Kappa | Authors: | Gardberg, A.S, Dealwis, C. | Deposit date: | 2006-10-12 | Release date: | 2007-10-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for passive immunotherapy of Alzheimer's disease Proc.Natl.Acad.Sci.Usa, 104, 2007
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1NBV
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![BU of 1nbv by Molmil](/molmil-images/mine/1nbv) | |