1QS8
 
 | | Crystal structure of the P. vivax aspartic proteinase plasmepsin complexed with the inhibitor pepstatin A | | Descriptor: | ACETATE ION, PEPSTATIN A, PLASMEPSIN | | Authors: | Khazanovich Bernstein, N, Cherney, M.M, Yowell, C.A, Dame, J.B, James, M.N.G. | | Deposit date: | 1999-06-25 | | Release date: | 1999-07-07 | | Last modified: | 2013-02-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into the activation of P. vivax plasmepsin.
J.Mol.Biol., 329, 2003
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1MIQ
 | | Crystal structure of proplasmepsin from the human malarial pathogen Plasmodium vivax | | Descriptor: | plasmepsin | | Authors: | Bernstein, N.K, Cherney, M.M, Yowell, C.A, Dame, J.B, James, M.N. | | Deposit date: | 2002-08-23 | | Release date: | 2002-09-18 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into the activation of P. vivax plasmepsin.
J.Mol.Biol., 329, 2003
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5JOD
 | | Structure of proplasmepsin IV from Plasmodium falciparum | | Descriptor: | GLYCEROL, Proplasmepsin IV | | Authors: | Recacha, R, Akopjana, I, Tars, K, Jaudzems, K. | | Deposit date: | 2016-05-02 | | Release date: | 2016-08-17 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.528 Å) | | Cite: | Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins.
Acta Crystallogr.,Sect.F, 72, 2016
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5BWY
 | | Structure of proplasmepsin II from Plasmodium falciparum, Space Group P43212 | | Descriptor: | Plasmepsin-2 | | Authors: | Recacha, R, Akopjana, I, Tars, K, Jaudzems, K. | | Deposit date: | 2015-06-08 | | Release date: | 2015-12-16 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.644 Å) | | Cite: | Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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4Z22
 | | structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor DR718A | | Descriptor: | 2-amino-7-phenyl-3-{[(2R,5S)-5-phenyltetrahydrofuran-2-yl]methyl}quinazolin-4(3H)-one, Plasmepsin-2 | | Authors: | Recacha, R, Leitans, J, Tars, K, Jaudzems, K. | | Deposit date: | 2015-03-28 | | Release date: | 2016-01-13 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV.
J.Med.Chem., 59, 2016
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