1QS8

Crystal structure of the P. vivax aspartic proteinase plasmepsin complexed with the inhibitor pepstatin A

Summary for 1QS8

Entry DOI	10.2210/pdb1qs8/pdb
Related PRD ID	PRD_000557
Descriptor	PLASMEPSIN, PEPSTATIN A, ACETATE ION, ... (4 entities in total)
Functional Keywords	plasmepsin, aspartic proteinase, haemoglobinase, malaria, pepstatin a, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Plasmodium vivax (malaria parasite P. vivax) More
Total number of polymer chains	4
Total formula weight	75807.57
Authors	Khazanovich Bernstein, N.,Cherney, M.M.,Yowell, C.A.,Dame, J.B.,James, M.N.G. (deposition date: 1999-06-25, release date: 1999-07-07, Last modification date: 2013-02-27)
Primary citation	Bernstein, N.K.,Cherney, M.M.,Yowell, C.A.,Dame, J.B.,James, M.N. Structural insights into the activation of P. vivax plasmepsin. J.Mol.Biol., 329:505-524, 2003 Cited by PubMed: 12767832 DOI: 10.1016/S0022-2836(03)00444-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation