1PW9
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![BU of 1pw9 by Molmil](/molmil-images/mine/1pw9) | High resolution crystal structure of an active recombinant fragment of human lung surfactant protein D | Descriptor: | CALCIUM ION, Pulmonary surfactant-associated protein D | Authors: | Shrive, A.K, Tharia, H.A, Strong, P, Kishore, U, Burns, I, Rizkallah, P.J, Reid, K.B, Greenhough, T.J. | Deposit date: | 2003-07-01 | Release date: | 2003-08-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D J.Mol.Biol., 331, 2003
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1PWA
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![BU of 1pwa by Molmil](/molmil-images/mine/1pwa) | Crystal structure of Fibroblast Growth Factor 19 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ... | Authors: | Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L. | Deposit date: | 2003-07-01 | Release date: | 2004-01-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity. Biochemistry, 43, 2004
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1PWB
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![BU of 1pwb by Molmil](/molmil-images/mine/1pwb) | High resolution crystal structure of an active recombinant fragment of human lung surfactant protein D with maltose | Descriptor: | CALCIUM ION, Pulmonary surfactant-associated protein D, alpha-D-glucopyranose, ... | Authors: | Shrive, A.K, Tharia, H.A, Strong, P, Kishore, U, Burns, I, Rizkallah, P.J, Reid, K.B, Greenhough, T.J. | Deposit date: | 2003-07-01 | Release date: | 2003-08-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D J.Mol.Biol., 331, 2003
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1PWC
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![BU of 1pwc by Molmil](/molmil-images/mine/1pwc) | penicilloyl acyl enzyme complex of the Streptomyces R61 DD-peptidase with penicillin G | Descriptor: | D-alanyl-D-alanine carboxypeptidase, OPEN FORM - PENICILLIN G | Authors: | Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. | Deposit date: | 2003-07-01 | Release date: | 2004-07-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin" J.Mol.Biol., 345, 2005
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1PWD
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![BU of 1pwd by Molmil](/molmil-images/mine/1pwd) | Covalent acyl enzyme complex of the Streptomyces R61 DD-peptidase with cephalosporin C | Descriptor: | (2R)-5-(acetyloxymethyl)-2-[(1R)-1-[[(5R)-5-azanyl-6-oxidanyl-6-oxidanylidene-hexanoyl]amino]-2-oxidanylidene-ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase precursor | Authors: | Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. | Deposit date: | 2003-07-01 | Release date: | 2004-07-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin" J.Mol.Biol., 345, 2005
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1PWE
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![BU of 1pwe by Molmil](/molmil-images/mine/1pwe) | Rat Liver L-Serine Dehydratase Apo Enzyme | Descriptor: | L-serine dehydratase | Authors: | Yamada, T, Komoto, J, Takata, Y, Ogawa, H, Takusagawa, F. | Deposit date: | 2003-07-01 | Release date: | 2003-12-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of serine dehydratase from rat liver. Biochemistry, 42, 2003
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1PWF
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![BU of 1pwf by Molmil](/molmil-images/mine/1pwf) | One Sugar Pucker Fits All: Pairing Versatility Despite Conformational Uniformity in TNA | Descriptor: | 5'-D(*GP*CP*GP*TP*AP*(2MU)P*(FA2)P*CP*GP*C)-3', SPERMINE | Authors: | Pallan, P.S, Wilds, C.J, Wawrzak, Z, Krishnamurthy, R, Eschenmoser, A, Egli, M. | Deposit date: | 2003-07-01 | Release date: | 2004-07-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis. ANGEW.CHEM.INT.ED.ENGL., 42, 2003
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1PWG
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![BU of 1pwg by Molmil](/molmil-images/mine/1pwg) | Covalent Penicilloyl Acyl Enzyme Complex Of The Streptomyces R61 DD-Peptidase With A Highly Specific Penicillin | Descriptor: | (2R,4S)-2-[(1R)-1-{[(6S)-6-carboxy-6-(glycylamino)hexanoyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase | Authors: | Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. | Deposit date: | 2003-07-01 | Release date: | 2004-07-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.074 Å) | Cite: | Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin" J.Mol.Biol., 345, 2005
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1PWH
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![BU of 1pwh by Molmil](/molmil-images/mine/1pwh) | Rat Liver L-Serine Dehydratase- Complex with PYRIDOXYL-(O-METHYL-SERINE)-5-MONOPHOSPHATE | Descriptor: | L-serine dehydratase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-O-METHYL-L-SERINE, POTASSIUM ION | Authors: | Yamada, T, Komoto, J, Takata, Y, Ogawa, H, Takusagawa, F. | Deposit date: | 2003-07-01 | Release date: | 2003-12-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of serine dehydratase from rat liver. Biochemistry, 42, 2003
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1PWJ
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![BU of 1pwj by Molmil](/molmil-images/mine/1pwj) | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly | Descriptor: | dynein light chain-2 | Authors: | Wang, W, Lo, K.W.-H, Kan, H.-M, Fan, J.-S, Zhang, M. | Deposit date: | 2003-07-02 | Release date: | 2003-10-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of the Domain-swapped Dimer Assembly J.Biol.Chem., 278, 2003
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1PWK
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![BU of 1pwk by Molmil](/molmil-images/mine/1pwk) | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly | Descriptor: | dynein light chain-2 | Authors: | Wang, W, Lo, K.W.-H, Kan, H.-M, Fan, J.-S, Zhang, M. | Deposit date: | 2003-07-02 | Release date: | 2003-10-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of the Domain-swapped Dimer Assembly J.Biol.Chem., 278, 2003
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1PWL
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![BU of 1pwl by Molmil](/molmil-images/mine/1pwl) | Crystal structure of human Aldose Reductase complexed with NADP and Minalrestat | Descriptor: | 2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase | Authors: | El-Kabbani, O, Darmanin, C, Schneider, T.R, Hazemann, I, Ruiz, F, Oka, M, Joachimiak, A, Schulze-Briese, C, Tomizaki, T, Mitschler, A, Podjarny, A. | Deposit date: | 2003-07-02 | Release date: | 2004-02-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors PROTEINS, 55, 2004
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1PWM
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![BU of 1pwm by Molmil](/molmil-images/mine/1pwm) | Crystal structure of human Aldose Reductase complexed with NADP and Fidarestat | Descriptor: | (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | El-Kabbani, O, Darmanin, C, Schneider, T.R, Hazemann, I, Ruiz, F, Oka, M, Joachimiak, A, Schulze-Briese, C, Tomizaki, T, Mitschler, A, Podjarny, A. | Deposit date: | 2003-07-02 | Release date: | 2004-02-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (0.92 Å) | Cite: | Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors PROTEINS, 55, 2004
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1PWO
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![BU of 1pwo by Molmil](/molmil-images/mine/1pwo) | |
1PWP
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![BU of 1pwp by Molmil](/molmil-images/mine/1pwp) | Crystal Structure of the Anthrax Lethal Factor complexed with Small Molecule Inhibitor NSC 12155 | Descriptor: | Lethal factor, N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA, ZINC ION | Authors: | Wong, T.Y, Schwarzenbacher, R, Liddington, R.C. | Deposit date: | 2003-07-02 | Release date: | 2004-01-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Identification of small molecule inhibitors of anthrax lethal factor. Nat.Struct.Mol.Biol., 11, 2004
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1PWQ
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![BU of 1pwq by Molmil](/molmil-images/mine/1pwq) | Crystal structure of Anthrax Lethal Factor complexed with Thioacetyl-Tyr-Pro-Met-Amide, a metal-chelating peptidyl small molecule inhibitor | Descriptor: | Lethal factor, N-(SULFANYLACETYL)TYROSYLPROLYLMETHIONINAMIDE, ZINC ION | Authors: | Wong, T.Y, Schwarzenbacher, R, Liddington, R.C. | Deposit date: | 2003-07-02 | Release date: | 2004-01-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat.Struct.Mol.Biol., 11, 2004
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1PWT
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![BU of 1pwt by Molmil](/molmil-images/mine/1pwt) | THERMODYNAMIC ANALYSIS OF ALPHA-SPECTRIN SH3 AND TWO OF ITS CIRCULAR PERMUTANTS WITH DIFFERENT LOOP LENGTHS: DISCERNING THE REASONS FOR RAPID FOLDING IN PROTEINS | Descriptor: | ALPHA SPECTRIN | Authors: | Martinez, J.C, Viguera, A.R, Berisio, R, Wilmanns, M, Mateo, P.L, Filmonov, V.V, Serrano, L. | Deposit date: | 1998-10-06 | Release date: | 1999-05-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Thermodynamic analysis of alpha-spectrin SH3 and two of its circular permutants with different loop lengths: discerning the reasons for rapid folding in proteins. Biochemistry, 38, 1999
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1PWU
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![BU of 1pwu by Molmil](/molmil-images/mine/1pwu) | Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases. | Descriptor: | 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE, Lethal factor, ZINC ION | Authors: | Wong, T.Y, Schwarzenbacher, R, Liddington, R.C. | Deposit date: | 2003-07-02 | Release date: | 2004-02-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat.Struct.Mol.Biol., 11, 2004
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1PWV
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![BU of 1pwv by Molmil](/molmil-images/mine/1pwv) | |
1PWW
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1PWX
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![BU of 1pwx by Molmil](/molmil-images/mine/1pwx) | Crystal structure of the haloalcohol dehalogenase HheC complexed with bromide | Descriptor: | BROMIDE ION, halohydrin dehalogenase | Authors: | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2003-07-02 | Release date: | 2003-10-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site EMBO J., 22, 2003
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1PWY
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![BU of 1pwy by Molmil](/molmil-images/mine/1pwy) | CRYSTAL STRUCTURE OF HUMAN PNP COMPLEXED WITH ACYCLOVIR | Descriptor: | 9-HYROXYETHOXYMETHYLGUANINE, Purine nucleoside phosphorylase, SULFATE ION | Authors: | Dos Santos, D.M, Canduri, F, Pereira, J.H, Vinicius Bertacine Dias, M, Silva, R.G, Mendes, M.A, Palma, M.S, Basso, L.A, De Azevedo, W.F, Santos, D.S. | Deposit date: | 2003-07-02 | Release date: | 2004-03-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir. Biochem.Biophys.Res.Commun., 308, 2003
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1PWZ
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![BU of 1pwz by Molmil](/molmil-images/mine/1pwz) | Crystal structure of the haloalcohol dehalogenase HheC complexed with (R)-styrene oxide and chloride | Descriptor: | CHLORIDE ION, R-STYRENE OXIDE, halohydrin dehalogenase | Authors: | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2003-07-02 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site EMBO J., 22, 2003
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1PX0
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![BU of 1px0 by Molmil](/molmil-images/mine/1px0) | Crystal structure of the haloalcohol dehalogenase HheC complexed with the haloalcohol mimic (R)-1-para-nitro-phenyl-2-azido-ethanol | Descriptor: | (R)-1-PARA-NITRO-PHENYL-2-AZIDO-ETHANOL, halohydrin dehalogenase | Authors: | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2003-07-02 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site EMBO J., 22, 2003
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1PX2
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![BU of 1px2 by Molmil](/molmil-images/mine/1px2) | Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP (Form 1) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Synapsin I | Authors: | Brautigam, C.A, Chelliah, Y, Deisenhofer, J. | Deposit date: | 2003-07-02 | Release date: | 2004-03-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I. J.Biol.Chem., 279, 2004
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