2L9D
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![BU of 2l9d by Molmil](/molmil-images/mine/2l9d) | Solution structure of the protein YP_546394.1, the first structural representative of the pfam family PF12112 | Descriptor: | Uncharacterized protein | Authors: | Mohanty, B, Serrano, P, Geralt, M, Horst, R, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | Deposit date: | 2011-02-08 | Release date: | 2011-03-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the protein YP_546394.1, the first structural representative of the pfam family PF12112 To be Published
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3LRU
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![BU of 3lru by Molmil](/molmil-images/mine/3lru) | |
2RAU
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4UUQ
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![BU of 4uuq by Molmil](/molmil-images/mine/4uuq) | Crystal structure of human mono-glyceride lipase in complex with SAR127303 | Descriptor: | 4-({[(4-chlorophenyl)sulfonyl]amino}methyl)piperidine-1-carboxylic acid, MONOGLYCERIDE LIPASE | Authors: | Griebel, G, Pichat, P, Beeske, S, Leroy, T, Redon, N, Francon, D, Bert, L, Even, L, Lopez-Grancha, M, Tolstykh, T, Sun, F, Yu, Q, Brittain, S, Arlt, H, He, T, Zhang, B, Wiederschain, D, Bertrand, T, Houtman, J, Rak, A, Vallee, F, Michot, N, Auge, F, Menet, V, Bergis, O.E, George, P, Avenet, P, Mikol, V, Didier, M, Escoubet, J. | Deposit date: | 2014-07-30 | Release date: | 2015-01-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Selective Blockade of the Hydrolysis of the Endocannabinoid 2-Arachidonoylglycerol Impairs Learning and Memory Performance While Producing Antinociceptive Activity in Rodents. Sci.Rep., 5, 2015
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5IAY
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![BU of 5iay by Molmil](/molmil-images/mine/5iay) | NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide | Descriptor: | E3 ubiquitin-protein ligase UHRF1, Spacer | Authors: | Fang, J, Cheng, J, Wang, J, Zhang, Q, Liu, M, Gong, R, Wang, P, Zhang, X, Feng, Y, Lan, W, Gong, Z, Tang, C, Wong, J, Yang, H, Cao, C, Xu, Y. | Deposit date: | 2016-02-22 | Release date: | 2016-04-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition Nat Commun, 7, 2016
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1Q68
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![BU of 1q68 by Molmil](/molmil-images/mine/1q68) | Solution structure of T-cell surface glycoprotein CD4 and Proto-oncogene tyrosine-protein kinase LCK fragments | Descriptor: | Proto-oncogene tyrosine-protein kinase LCK, T-cell surface glycoprotein CD4, ZINC ION | Authors: | Kim, P.W, Sun, Z.Y, Blacklow, S.C, Wagner, G, Eck, M.J. | Deposit date: | 2003-08-12 | Release date: | 2003-11-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8. Science, 301, 2003
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4PKX
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![BU of 4pkx by Molmil](/molmil-images/mine/4pkx) | The structure of a conserved Piezo channel domain reveals a novel beta sandwich fold | Descriptor: | Protein C10C5.1, isoform i | Authors: | Kamajaya, A, Kaiser, J, Lee, J, Reid, M, Rees, D.C. | Deposit date: | 2014-05-15 | Release date: | 2014-10-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | The Structure of a Conserved Piezo Channel Domain Reveals a Topologically Distinct beta Sandwich Fold. Structure, 22, 2014
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3VJ7
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![BU of 3vj7 by Molmil](/molmil-images/mine/3vj7) | Crystal structure of the carboxy-terminal ribonuclease domain of Colicin E5 R33Q mutant | Descriptor: | 2'-DEOXYURIDINE 3'-MONOPHOSPHATE, 2-AMINO-9-(2-DEOXY-3-O-PHOSPHONOPENTOFURANOSYL)-1,9-DIHYDRO-6H-PURIN-6-ONE, Colicin-E5 | Authors: | Yajima, S, Inoue, S, Fushinobu, S, Ogawa, T, Hidaka, M, Masaki, H. | Deposit date: | 2011-10-13 | Release date: | 2011-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Identification of the catalytic residues of sequence-specific and histidine-free ribonuclease colicin E5 J.Biochem., 152, 2012
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3VIS
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![BU of 3vis by Molmil](/molmil-images/mine/3vis) | Crystal structure of cutinase Est119 from Thermobifida alba AHK119 | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Esterase | Authors: | Kitadokoro, K, Thumarat, U, Nakamura, R, Nishimura, K, Karatani, H, Suzuki, H, Kawai, F. | Deposit date: | 2011-10-11 | Release date: | 2012-04-11 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of cutinase Est119 from Thermobida alba AHK119 that can degrade modpolyethylene terephthalate at 1.76 A resolution. POLYM.DEGRAD.STAB., 97, 2012
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4ZXF
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![BU of 4zxf by Molmil](/molmil-images/mine/4zxf) | Crystal Structure of a Soluble Variant of Monoglyceride Lipase from Saccharomyces Cerevisiae in Complex with a Substrate Analog | Descriptor: | 1-{3-[(R)-hydroxy(octadecyloxy)phosphoryl]propyl}triaza-1,2-dien-2-ium, Monoglyceride lipase, NITRATE ION, ... | Authors: | Aschauer, P, Lichtenegger, J, Rengachari, S, Gruber, K, Oberer, M. | Deposit date: | 2015-05-20 | Release date: | 2016-05-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p. Biochim.Biophys.Acta, 1861, 2016
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4PKE
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![BU of 4pke by Molmil](/molmil-images/mine/4pke) | The structure of a conserved Piezo channel domain reveals a novel beta sandwich fold | Descriptor: | PLATINUM (II) ION, Protein C10C5.1, isoform i | Authors: | Kamajaya, A, Kaiser, J, Lee, J, Reid, M, Rees, D.C. | Deposit date: | 2014-05-14 | Release date: | 2014-10-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Structure of a Conserved Piezo Channel Domain Reveals a Topologically Distinct beta Sandwich Fold. Structure, 22, 2014
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2GOM
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4LHE
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![BU of 4lhe by Molmil](/molmil-images/mine/4lhe) | |
6S6N
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6S6M
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3DB4
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![BU of 3db4 by Molmil](/molmil-images/mine/3db4) | Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 | Descriptor: | E3 ubiquitin-protein ligase UHRF1, SULFATE ION | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-05-30 | Release date: | 2008-09-16 | Last modified: | 2012-04-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein. J.Biol.Chem., 286, 2011
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4F2H
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7Z2X
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![BU of 7z2x by Molmil](/molmil-images/mine/7z2x) | Wild-type ferulic acid esterase from Lactobacillus buchneri | Descriptor: | Ferulic acid esterase | Authors: | Mogodiniyai, K.K, Reichenbach, T, Kalyani, D.C, Keskitalo, M.M, Divne, C. | Deposit date: | 2022-03-01 | Release date: | 2022-11-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state. Front Microbiol, 13, 2022
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7Z2U
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![BU of 7z2u by Molmil](/molmil-images/mine/7z2u) | Wild-type ferulic acid esterase from Lactobacillus buchneri in complex with ferulate | Descriptor: | 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, CALCIUM ION, Ferulic acid esterase | Authors: | Mogodiniyai, K.K, Reichenbach, T, Kalyani, D.C, Keskitalo, M.M, Divne, C. | Deposit date: | 2022-02-28 | Release date: | 2022-11-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state. Front Microbiol, 13, 2022
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7Z2V
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![BU of 7z2v by Molmil](/molmil-images/mine/7z2v) | Ferulic acid esterase variant S114A from Lactobacillus buchneri | Descriptor: | ACETATE ION, CALCIUM ION, Ferulic acid esterase | Authors: | Mogodiniyai, K.K, Reichenbach, T, Kalyani, D.C, Keskitalo, M.M, Divne, C. | Deposit date: | 2022-02-28 | Release date: | 2022-11-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state. Front Microbiol, 13, 2022
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7ZPG
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![BU of 7zpg by Molmil](/molmil-images/mine/7zpg) | CRYSTAL STRUCTURE OF HUMAN MONOGLYCERIDE LIPASE WITH LIGAND | Descriptor: | Monoglyceride lipase, [(7R,9aR)-7-(4-chlorophenyl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl]-(2-bromanyl-3-methoxy-phenyl)methanone | Authors: | Kemble, A, Hornsperger, B, Ruf, I, Richter, H, Benz, J, Kuhn, B, Heer, D, Wittwer, M, Engelhardt, B, Grether, U, Collin, L, Leibrock, L. | Deposit date: | 2022-04-27 | Release date: | 2022-09-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature. Plos One, 17, 2022
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5C5G
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5CML
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![BU of 5cml by Molmil](/molmil-images/mine/5cml) | Crystal structure of the Esterase domain from Rhodothermus marinus Rmar_1206 protein | Descriptor: | OsmC family protein, TRIETHYLENE GLYCOL | Authors: | Marles-Wright, J, Wardrope, C, Jensen, M.-B.V, Horsfall, L.E, Togneri, P.D, Rosser, S.J. | Deposit date: | 2015-07-16 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Characterisation of a New Family of Carboxyl Esterases with an OsmC Domain. Plos One, 11, 2016
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8AQF
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![BU of 8aqf by Molmil](/molmil-images/mine/8aqf) | CRYSTAL STRUCTURE OF HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND LEI-515 | Descriptor: | 1-[(~{R})-[2-chloranyl-4-[(2~{S},3~{S})-4-(3-chlorophenyl)-2,3-dimethyl-piperazin-1-yl]carbonyl-phenyl]sulfinyl]-3,3-bis(fluoranyl)pentan-2-one, Monoglyceride lipase | Authors: | Jiang, M, Huizenga, M, Wirt, J, Paloczi, J, Amedi, A, van der Berg, R, Benz, J, Collin, L, Deng, H, Driever, W, Florea, B, Grether, U, Janssen, A, Heitman, L, Lam, T.W, Mohr, F, Pavlovic, A, Ruf, I, Rutjes, H, Stevens, F, van der Vliet, D, van der Wel, T, Wittwer, M, Boeckel, C, Pacher, P, Hohmann, A, van der Stelt, M. | Deposit date: | 2022-08-12 | Release date: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Discovery of a peripheral restricted, reversible monoacylglycerol lipase inhibitor that reduces liver injury and chemotherapy-induced neuropathy To Be Published
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5D6T
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![BU of 5d6t by Molmil](/molmil-images/mine/5d6t) | Crystal Structure of Aspergillus clavatus Sph3 in complex with GalNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, CHLORIDE ION, SPHERULIN-4, ... | Authors: | Bamford, N.C, Little, D.J, Howell, P.L. | Deposit date: | 2015-08-12 | Release date: | 2015-09-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus. J.Biol.Chem., 290, 2015
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