1Z2C
| Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP | Descriptor: | Diaphanous protein homolog 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Rose, R, Weyand, M, Lammers, M, Ishizaki, T, Ahmadian, M.R, Wittinghofer, A. | Deposit date: | 2005-03-08 | Release date: | 2005-05-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and mechanistic insights into the interaction between Rho and mammalian Dia. Nature, 435, 2005
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2BNX
| Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1 | Descriptor: | CHLORIDE ION, DIAPHANOUS PROTEIN HOMOLOG 1 | Authors: | Otomo, T, Otomo, C, Tomchick, D.R, Machius, M, Rosen, M.K. | Deposit date: | 2005-04-05 | Release date: | 2005-06-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of Rho Gtpase-Mediated Activation of the Formin Mdia1 Mol.Cell, 18, 2005
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2BAP
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2F31
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3EG5
| Crystal structure of MDIA1-TSH GBD-FH3 in complex with CDC42-GMPPNP | Descriptor: | Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Lammers, M, Meyer, S, Kuehlmann, D, Wittinghofer, A. | Deposit date: | 2008-09-10 | Release date: | 2008-10-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Specificity of Interactions between mDia Isoforms and Rho Proteins J.Biol.Chem., 283, 2008
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3O4X
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3OBV
| Autoinhibited Formin mDia1 Structure | Descriptor: | Protein diaphanous homolog 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | Authors: | Tomchick, D.R, Rosen, M.K, Otomo, T. | Deposit date: | 2010-08-09 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of the Formin mDia1 in autoinhibited conformation. Plos One, 5, 2010
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4DVG
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4UWX
| Structure of liprin-alpha3 in complex with mDia1 Diaphanous- inhibitory domain | Descriptor: | LIPRIN-ALPHA-3, NICKEL (II) ION, PROTEIN DIAPHANOUS HOMOLOG 1, ... | Authors: | Brenig, J, de Boor, S, Knyphausen, P, Kuhlmann, N, Wroblowski, S, Baldus, L, Scislowski, L, Artz, O, Trauschies, P, Baumann, U, Neundorf, I, Lammers, M. | Deposit date: | 2014-08-15 | Release date: | 2015-05-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and Biochemical Basis for the Inhibitory Effect of Liprin-Alpha3 on Mouse Diaphanous 1 (Mdia1) Function. J.Biol.Chem., 290, 2015
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4YC7
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4YDH
| The structure of human FMNL1 N-terminal domains bound to Cdc42 | Descriptor: | Cell division control protein 42 homolog, Formin-like protein 1, MAGNESIUM ION, ... | Authors: | Kuhn, S, Anand, K, Geyer, M. | Deposit date: | 2015-02-22 | Release date: | 2015-05-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation. Nat Commun, 6, 2015
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8FG1
| Human diaphanous inhibitory domain bound to diaphanous autoregulatory domain | Descriptor: | Protein diaphanous homolog 1 | Authors: | Ramirez, L.M.S, Theophall, G, Premo, A, Manigrasso, M, Yepuri, G, Burz, D, Ramasamy, R, Schmidt, A.M, Shekhtman, A. | Deposit date: | 2022-12-12 | Release date: | 2023-10-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity. J.Biol.Chem., 299, 2023
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9AZP
| INF2 at the Barbed End of F-Actin with Incoming Profilin-Actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Palmer, N.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2024-03-11 | Release date: | 2024-05-29 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.79 Å) | Cite: | Mechanisms of actin filament severing and elongation by formins. Nature, 632, 2024
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