6FLF
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6ZXQ
| Adenylosuccinate Synthetase from H. pylori in complex with HDA, GDP, IMO, Mg | Descriptor: | 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE, Adenylosuccinate synthetase, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Bubic, A, Stefanic, Z. | Deposit date: | 2020-07-30 | Release date: | 2021-08-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site Int.J.Biol.Macromol., 2023
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5I34
| Adenylosuccinate synthetase from Cryptococcus neoformans complexed with GDP and IMP | Descriptor: | Adenylosuccinate synthetase, GUANOSINE-5'-DIPHOSPHATE, INOSINIC ACID | Authors: | Blundell, R.D, Williams, S.J, Ericsson, D, Fraser, J.A, Kobe, B. | Deposit date: | 2016-02-09 | Release date: | 2016-08-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans. Acs Infect Dis., 2, 2016
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3HID
| Crystal structure of adenylosuccinate synthetase from Yersinia pestis CO92 | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, Adenylosuccinate synthetase | Authors: | Zhang, R, Zhou, M, Peterson, S, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-05-19 | Release date: | 2009-06-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of the adenylosuccinate synthetase from Yersinia pestis CO92 To be Published
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7ODX
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9F17
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6FM0
| Deoxyguanylosuccinate synthase (DgsS) and ATP structure at 1.7 Angstrom resolution | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase | Authors: | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | Deposit date: | 2018-01-29 | Release date: | 2019-06-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes. Science, 372, 2021
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7VF6
| The crystal structure of PurZ0 | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... | Authors: | Tong, Y, Zhang, Y. | Deposit date: | 2021-09-10 | Release date: | 2023-05-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.703 Å) | Cite: | Alternative Z-genome biosynthesis pathway shows evolutionary progression from Archaea to phage. Nat Microbiol, 8, 2023
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4M9D
| The Crystal structure of an adenylosuccinate synthetase from Bacillus anthracis str. Ames Ancestor in complex with AMP. | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate synthetase, ... | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-14 | Release date: | 2013-08-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.821 Å) | Cite: | The Crystal structure of an adenylosuccinate synthetase from Bacillus anthracis str. Ames Ancestor in complex with AMP. To be Published
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8QWA
| Adenylosuccinate Synthetase from H. pylori in complex with PLP and IMP | Descriptor: | Adenylosuccinate synthetase, GLYCEROL, INOSINIC ACID, ... | Authors: | Bzowska, A, Narczyk, M, Maksymiuk, W. | Deposit date: | 2023-10-19 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Vitamin B6 inhibits activity of Helicobacter pylori adenylosuccinate synthetase and growth of reference and clinical, antibiotic-resistant H. pylori strains. J Enzyme Inhib Med Chem, 39, 2024
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6C25
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2V40
| Human Adenylosuccinate synthetase isozyme 2 in complex with GDP | Descriptor: | ADENYLOSUCCINATE SYNTHETASE ISOZYME 2, GUANOSINE-5'-DIPHOSPHATE | Authors: | Welin, M, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2007-06-27 | Release date: | 2007-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Human Adenylosuccinate Synthetase Isozyme 2 in Complex with Gdp To be Published
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6BS7
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6FM3
| Deoxyguanylosuccinate synthase (DgsS) structure with ADP at 1.9 Angstrom resolution | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Adenylosuccinate synthetase, CHLORIDE ION | Authors: | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | Deposit date: | 2018-01-30 | Release date: | 2019-06-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP0, dGMP, Magnesium at 2.3 Angstrom resolution To Be Published
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3UE9
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7PVO
| Adenylosuccinate Synthetase from H. pylori in complex with IMP | Descriptor: | Adenylosuccinate synthetase, INOSINIC ACID, SULFATE ION | Authors: | Narczyk, M, Bzowska, A, Maksymiuk, W. | Deposit date: | 2021-10-05 | Release date: | 2022-11-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site. Int.J.Biol.Macromol., 226, 2023
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1P9B
| Structure of fully ligated Adenylosuccinate synthetase from Plasmodium falciparum | Descriptor: | 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE, Adenylosuccinate Synthetase, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Eaazhisai, K, Jayalakshmi, R, Gayathri, P, Anand, R.P, Sumathy, K, Balaram, H, Murthy, M.R. | Deposit date: | 2003-05-10 | Release date: | 2004-02-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Fully Ligated Adenylosuccinate Synthetase from Plasmodium falciparum. J.Mol.Biol., 335, 2004
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1QF5
| DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF AN ENZYME BOUND BISUBSTRATE HYBRID INHIBITOR OF ADENYLOSUCCINATE SYNTHETASE | Descriptor: | (C8-S)-HYDANTOCIDIN 5'-PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Hanessian, S, Lu, P.-P, Sanceau, J.-Y, Chemla, P, Prade, L, Gohda, K, Cowan-Jacob, S.W, Fonne-Pfister, R. | Deposit date: | 1999-04-06 | Release date: | 1999-12-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | An enzyme-bound bisubstrate hybrid inhibitor of adenylosuccinate synthetase Angew.Chem.Int.Ed.Engl., 38, 1999
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1ADE
| STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE PH 7 AT 25 DEGREES CELSIUS | Descriptor: | ADENYLOSUCCINATE SYNTHETASE | Authors: | Silva, M.M, Poland, B.W, Hoffman, C.M, Fromm, H.J, Honzatko, R.B. | Deposit date: | 1995-09-14 | Release date: | 1996-01-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Refined crystal structures of unligated adenylosuccinate synthetase from Escherichia coli. J.Mol.Biol., 254, 1995
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2GCQ
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6JRQ
| Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus | Descriptor: | 1,2-ETHANEDIOL, Adenylosuccinate synthetase, INOSINIC ACID | Authors: | Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2019-04-05 | Release date: | 2020-04-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus HB8 To Be Published
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1IWE
| IMP Complex of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase | Descriptor: | ACETATE ION, Adenylosuccinate Synthetase, INOSINIC ACID, ... | Authors: | Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B. | Deposit date: | 2002-05-04 | Release date: | 2002-08-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | IMP, GTP, and 6-phosphoryl-IMP complexes of recombinant mouse muscle adenylosuccinate synthetase. J.Biol.Chem., 277, 2002
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6FKO
| Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, dGMP, hadacidin at 2.1 Angstrom resolution | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase, ... | Authors: | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | Deposit date: | 2018-01-24 | Release date: | 2019-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, dGMP, HAdacidin at 2.1 Angstrom resolution To Be Published
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1LON
| Crystal Structure of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase Complexed with 6-phosphoryl-IMP, GDP and Hadacidin | Descriptor: | 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, HADACIDIN, ... | Authors: | Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B. | Deposit date: | 2002-05-06 | Release date: | 2002-08-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | IMP, GTP, and 6-phosphoryl-IMP complexes of recombinant mouse muscle adenylosuccinate synthetase. J.Biol.Chem., 277, 2002
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4M0G
| The crystal structure of an adenylosuccinate synthetase from Bacillus anthracis str. Ames Ancestor. | Descriptor: | Adenylosuccinate synthetase, CHLORIDE ION | Authors: | Tan, K, Zhou, M, Zhang, R, Kwon, K, Anderson, W.F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-01 | Release date: | 2013-08-14 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | The crystal structure of an adenylosuccinate synthetase from Bacillus anthracis str. Ames Ancestor. To be Published
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