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6I57
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BU of 6i57 by Molmil
NMR structure of the third TPR domain of the human SPAG1 protein
Descriptor: Sperm-associated antigen 1
Authors:Chagot, M.E, Quinternet, M.
Deposit date:2018-11-13
Release date:2019-06-05
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Binding properties of the quaternary assembly protein SPAG1.
Biochem.J., 476, 2019
2KC7
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BU of 2kc7 by Molmil
Solution NMR structure of Bacteroides fragilis protein BF1650. Northeast Structural Genomics Consortium target BfR218
Descriptor: bfr218_protein
Authors:Eletsky, A, Wu, Y, Sukumaran, D, Lee, H, Lee, D.Y, Jiang, M, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-12-17
Release date:2009-01-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution NMR structure of Bacteroides fragilis protein BF1650. Northeast Structural Genomics Consortium target BfR218
To be Published
2BUG
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BU of 2bug by Molmil
Solution structure of the TPR domain from Protein phosphatase 5 in complex with Hsp90 derived peptide
Descriptor: HSP90, SERINE/THREONINE PROTEIN PHOSPHATASE 5
Authors:Cliff, M.J, Harris, R, Barford, D, Ladbury, J.E, Williams, M.A.
Deposit date:2005-06-13
Release date:2006-03-16
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Conformational Diversity in the Tpr Domain-Mediated Interaction of Protein Phosphatase 5 with Hsp90.
Structure, 14, 2006
6ZBK
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BU of 6zbk by Molmil
Crystal structure of the human complex between RPAP3 and TRBP
Descriptor: RISC-loading complex subunit TARBP2, RNA polymerase II-associated protein 3
Authors:Charron, C, Abel, Y, Charpentier, B, Rederstorff, M.
Deposit date:2020-06-08
Release date:2021-06-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity.
Nucleic Acids Res., 50, 2022
4GCO
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BU of 4gco by Molmil
Central domain of stress-induced protein-1 (STI-1) from C.elegans
Descriptor: Protein STI-1
Authors:Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2012-07-30
Release date:2012-08-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Central domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
2LNI
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BU of 2lni by Molmil
Solution NMR Structure of Stress-induced-phosphoprotein 1 STI1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4403E
Descriptor: Stress-induced-phosphoprotein 1
Authors:Tang, Y, Liu, G, Hamilton, K, Ciccosanti, C, Shastry, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-12-28
Release date:2012-03-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Northeast Structural Genomics Consortium Target HR4403E
To be Published
4CGV
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BU of 4cgv by Molmil
First TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD
Descriptor: GLYCEROL, HEAT SHOCK PROTEIN HSP 90-ALPHA, RNA POLYMERASE II-ASSOCIATED PROTEIN 3
Authors:Roe, S.M, Pal, M.
Deposit date:2013-11-26
Release date:2014-05-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1.
Structure, 22, 2014
6FD7
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BU of 6fd7 by Molmil
NMR structure of the first TPR domain of the human RPAP3 protein
Descriptor: RNA polymerase II-associated protein 3
Authors:Quinternet, M, Chagot, M.E, Manival, X.
Deposit date:2017-12-22
Release date:2018-08-01
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.
Structure, 26, 2018
3UPV
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BU of 3upv by Molmil
TPR2B-domain:pHsp70-complex of yeast Sti1
Descriptor: Heat shock protein SSA4, Heat shock protein STI1
Authors:Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H.
Deposit date:2011-11-18
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
5LYP
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BU of 5lyp by Molmil
Crystal structure of the Tpr Domain of Sgt2.
Descriptor: BORATE ION, Small glutamine-rich tetratricopeptide repeat-containing protein 2
Authors:Krysztofinska, E.M, Morgan, R.M.L, Thapaliya, A, Evans, N.J, Murray, J.W, Martinez-Lumbreras, S, Isaacson, R.L.
Deposit date:2016-09-28
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Front Mol Biosci, 4, 2017
5LYN
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BU of 5lyn by Molmil
Structure of the Tpr Domain of Sgt2 in complex with yeast Ssa1 peptide fragment
Descriptor: PRO-THR-VAL-GLU-GLU-VAL-ASP, Small glutamine-rich tetratricopeptide repeat-containing protein 2, ZINC ION
Authors:Krysztofinska, E.M, Evans, N.J, Thapaliya, A, Murray, J.W, Morgan, R.M.L, Martinez-Lumbreras, S, Isaacson, R.L.
Deposit date:2016-09-28
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Front Mol Biosci, 4, 2017
7NTF
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BU of 7ntf by Molmil
Cryo-EM structure of unliganded O-GlcNAc transferase
Descriptor: Isoform 1 of UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Authors:Meek, R.W, Blaza, J.N, Davies, G.J.
Deposit date:2021-03-09
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (5.32 Å)
Cite:Cryo-EM structure provides insights into the dimer arrangement of the O-linked beta-N-acetylglucosamine transferase OGT.
Nat Commun, 12, 2021
1A17
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BU of 1a17 by Molmil
TETRATRICOPEPTIDE REPEATS OF PROTEIN PHOSPHATASE 5
Descriptor: SERINE/THREONINE PROTEIN PHOSPHATASE 5, SULFATE ION
Authors:Das, A.K, Cohen, P.T.W, Barford, D.
Deposit date:1997-12-23
Release date:1998-04-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions.
EMBO J., 17, 1998
7KDT
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BU of 7kdt by Molmil
Human Tom70 in complex with SARS CoV2 Orf9b
Descriptor: Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 370, 2020
7DHG
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BU of 7dhg by Molmil
Crystal structure of SARS-CoV-2 Orf9b complex with human TOM70
Descriptor: Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:Gao, X, Zhu, K, Qin, B, Olieric, V, Wang, M, Cui, S.
Deposit date:2020-11-14
Release date:2021-05-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions.
Nat Commun, 12, 2021
3ESK
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BU of 3esk by Molmil
Structure of HOP TPR2A domain in complex with the non-cognate Hsc70 peptide ligand
Descriptor: Heat shock cognate 71 kDa protein, NICKEL (II) ION, Stress-induced-phosphoprotein 1
Authors:Kajander, T, Regan, L.
Deposit date:2008-10-06
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering.
J.Biol.Chem., 284, 2009
2VYI
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BU of 2vyi by Molmil
Crystal Structure of the TPR domain of Human SGT
Descriptor: SGTA PROTEIN
Authors:Dutta, S, Tan, Y.J.
Deposit date:2008-07-24
Release date:2008-08-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Functional Characterization of Human Sgt and its Interaction with Vpu of the Human Immunodeficiency Virus Type 1.
Biochemistry, 47, 2008
1ELR
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BU of 1elr by Molmil
Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD
Descriptor: HSP90-PEPTIDE MEEVD, NICKEL (II) ION, TPR2A-DOMAIN OF HOP
Authors:Scheufler, C, Brinker, A, Hartl, F.U, Moarefi, I.
Deposit date:2000-03-14
Release date:2000-04-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine.
Cell(Cambridge,Mass.), 101, 2000
2GW1
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BU of 2gw1 by Molmil
Crystal Structure of the Yeast Tom70
Descriptor: Mitochondrial precursor proteins import receptor
Authors:Wu, Y, Sha, B.
Deposit date:2006-05-03
Release date:2006-06-27
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of yeast mitochondrial outer membrane translocon member Tom70p.
Nat.Struct.Mol.Biol., 13, 2006
6FV0
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BU of 6fv0 by Molmil
Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of torsinA
Descriptor: DI(HYDROXYETHYL)ETHER, Kinesin light chain 1,Torsin-1A, nanobody
Authors:Pernigo, S, Dodding, M.P, Steiner, R.A.
Deposit date:2018-02-28
Release date:2018-03-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.
Elife, 7, 2018
7AI4
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BU of 7ai4 by Molmil
Crystal structure of the KLC1-TPR domain truncated from its nonTPR region ([A1-B6]-Delta-nonTPR fragment)
Descriptor: Isoform C of Kinesin light chain 1,Isoform C of Kinesin light chain 1
Authors:Menetrey, J, Llinas, P.
Deposit date:2020-09-26
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Structural investigations of the dynamics of the TPR domain of kinesin light chain
To Be Published
7AIE
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BU of 7aie by Molmil
Crystal structure of a truncated form of the KLC1-TPR domain ([A1-B5] fragment) - Monoclinic crystal form
Descriptor: Kinesin light chain 1, MAGNESIUM ION
Authors:Menetrey, J, Llinas, P.
Deposit date:2020-09-27
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.287 Å)
Cite:Structural investigations of the dynamics of the TPR domain of kinesin light chain
To Be Published
4GCN
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BU of 4gcn by Molmil
N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
Descriptor: Protein STI-1, TRIETHYLENE GLYCOL
Authors:Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2012-07-30
Release date:2012-08-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
6HFT
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BU of 6hft by Molmil
Hsp90 co-chaperone Cns1 from Saccharomyces cerevisiae (delta69)
Descriptor: Hsp70/Hsp90 co-chaperone CNS1, MAGNESIUM ION
Authors:Huber, E.M, Groll, M.
Deposit date:2018-08-21
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.
Mol.Cell, 74, 2019
6EJN
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BU of 6ejn by Molmil
The KLC2 TPR domain bound to the JIP3 leucine zipper domain
Descriptor: C-Jun-amino-terminal kinase-interacting protein 3, Kinesin light chain 2
Authors:Cockburn, J, Hesketh, S.J, Way, M.
Deposit date:2017-09-22
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Insights into Kinesin-1 Activation from the Crystal Structure of KLC2 Bound to JIP3.
Structure, 26, 2018

 

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