4JON
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4H87
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6CCD
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3VA4
| Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide | Descriptor: | Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2 | Authors: | Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D. | Deposit date: | 2011-12-28 | Release date: | 2012-02-01 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68. Biochemistry, 2012
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4QCJ
| Crystal Structure of OdhI from Corynebacterium glutamicum | Descriptor: | Oxoglutarate dehydrogenase inhibitor | Authors: | Labahn, J, Raasch, K, Eggeling, L, Bocola, M, Leitner, A, Bott, M. | Deposit date: | 2014-05-12 | Release date: | 2014-07-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Interaction of 2-oxoglutarate dehydrogenase OdhA with its inhibitor OdhI in Corynebacterium glutamicum: Mutants and a model. J.Biotechnol., 191, 2014
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7RJ3
| Crystal Structure of the Forkhead Associated (FHA) Domain of the Glycogen Accumulation Regulator (GarA) from Mycobacterium tuberculosis | Descriptor: | DI(HYDROXYETHYL)ETHER, Glycogen accumulation regulator GarA | Authors: | Minasov, G, Shuvalova, L, Pshenychnyi, S, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-07-20 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystal Structure of the Forkhead Associated (FHA) Domain of the Glycogen Accumulation Regulator (GarA) from Mycobacterium tuberculosis. To Be Published
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8WWY
| Crystal structure of mouse TIFA/TIFAB heterodimer | Descriptor: | (2R,5R)-hexane-2,5-diol, TRAF-interacting protein with FHA domain-containing protein A, TRAF-interacting protein with FHA domain-containing protein B | Authors: | Nakamura, T. | Deposit date: | 2023-10-27 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA. Proc.Natl.Acad.Sci.USA, 121, 2024
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1DMZ
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3VA1
| Crystal structure of the mammalian MDC1 FHA domain | Descriptor: | Mediator of DNA damage checkpoint protein 1, SULFATE ION | Authors: | Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D. | Deposit date: | 2011-12-28 | Release date: | 2012-02-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68. Biochemistry, 2012
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3VPY
| Crystal structure of Arabidopsis DDL FHA domain | Descriptor: | FHA domain-containing protein DDL | Authors: | Yuan, Y.A, Machida, S. | Deposit date: | 2012-03-15 | Release date: | 2013-02-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Arabidopsis thaliana Dawdle Forkhead-Associated Domain reveals a conserved phospho-threonine recognition cleft for Dicer-like1 binding. Mol Plant, 2013
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2N84
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1UHT
| Solution Structure of The FHA Domain of Arabidopsis thaliana Hypothetical Protein | Descriptor: | expressed protein | Authors: | Tomizawa, T, Inoue, M, Koshiba, S, Hayashi, F, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Shinozaki, K, Seki, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-07-10 | Release date: | 2004-01-10 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structure of The FHA Domain of Arabidopsis thaliana Hypothetical Protein To be Published
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1QU5
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2PIE
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2A0T
| NMR structure of the FHA1 domain of Rad53 in complex with a biological relevant phosphopeptide derived from Madt1 | Descriptor: | Hypothetical 73.8 kDa protein in SAS3-SEC17 intergenic region, residues 301-310, Serine/threonine-protein kinase RAD53 | Authors: | Mahajan, A, Yuan, C, Pike, B.L, Heierhorst, J, Chang, C.-F, Tsai, M.-D. | Deposit date: | 2005-06-16 | Release date: | 2005-11-08 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | FHA Domain-Ligand Interactions: Importance of Integrating Chemical and Biological Approaches J.Am.Chem.Soc., 127, 2005
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1R21
| Solution Structure of human Ki67 FHA Domain | Descriptor: | Antigen Ki-67 | Authors: | Byeon, I.J, Li, H, Tsai, M.D. | Deposit date: | 2003-09-25 | Release date: | 2003-12-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of Human Ki67 FHA Domain and its Binding to a Phosphoprotein Fragment from hNIFK Reveal Unique Recognition Sites and New Views to the Structural Basis of FHA Domain Functions J.Mol.Biol., 335, 2004
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4YM4
| Truncated Human TIFA in complex with its Thr9 phosphorylated N-terminal peptide 1-15 | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | Authors: | Weng, J.H, Wei, T.Y.W, Hsieh, Y.C, Huang, C.C.F, Wu, P.Y.G, Chen, E.S.W, Huang, K.F, Chen, C.J, Tsai, M.D. | Deposit date: | 2015-03-06 | Release date: | 2015-10-21 | Last modified: | 2015-10-28 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses. Biochemistry, 54, 2015
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4ZGI
| Structure of Truncated Human TIFA | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | Authors: | Weng, J.H, Wei, T.Y.W, Hsieh, Y.C, Huang, C.C.F, Wu, P.Y.G, Chen, E.S.W, Huang, K.F, Chen, C.J, Tsai, M.D. | Deposit date: | 2015-04-23 | Release date: | 2015-10-14 | Last modified: | 2015-10-28 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses. Biochemistry, 54, 2015
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1WLN
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3ELS
| Crystal Structure of Yeast Pml1p, Residues 51-204 | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Trowitzsch, S, Weber, G, Luehrmann, R, Wahl, M.C. | Deposit date: | 2008-09-23 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. J.Mol.Biol., 385, 2009
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3OUN
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6L9W
| Crystal structure of mouse TIFA (T9E/C36S mutant) | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2019-11-11 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity. Sci Rep, 10, 2020
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6L9V
| Crystal structure of mouse TIFA (T9D/C36S mutant) | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2019-11-11 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity. Sci Rep, 10, 2020
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6L9U
| Crystal structure of mouse TIFA | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2019-11-11 | Release date: | 2020-04-01 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity. Sci Rep, 10, 2020
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5YYZ
| Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide. | Descriptor: | Meiosis-specific protein HOP1, Meiosis-specific serine/threonine-protein kinase MEK1 | Authors: | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-12-11 | Release date: | 2018-10-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Structural insights into the recognition of phosphorylated Hop1 by Mek1 Acta Crystallogr D Struct Biol, 74, 2018
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