8PVQ
| Crystal Structure of Human PTX3 C-terminal domain | Descriptor: | Pentraxin-related protein PTX3 | Authors: | Levy, C.W. | Deposit date: | 2023-07-18 | Release date: | 2024-07-24 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Pentraxin 3 mediated crosslinking of heavy chain hyaluronan complexes: new insights from structural and biophysical studies To Be Published
|
|
8WV4
| C-reactive protein, pentamer | Descriptor: | C-reactive protein(1-205), CALCIUM ION | Authors: | Yadav, S, Vinothkumar, K.R. | Deposit date: | 2023-10-23 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Factors affecting macromolecule orientations in thin films formed in cryo-EM. Acta Crystallogr D Struct Biol, 80, 2024
|
|
8WV5
| C-reactive protein, decamer | Descriptor: | C-reactive protein(1-205), CALCIUM ION | Authors: | Yadav, S, Vinothkumar, K.R. | Deposit date: | 2023-10-23 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Factors affecting macromolecule orientations in thin films formed in cryo-EM. Acta Crystallogr D Struct Biol, 80, 2024
|
|
8B55
| Human ADGRG4 PTX-like domain | Descriptor: | Adhesion G-protein coupled receptor G4, MAGNESIUM ION | Authors: | Kieslich, B, Straeter, N. | Deposit date: | 2022-09-21 | Release date: | 2022-10-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | The dimerized pentraxin-like domain of the adhesion G protein-coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces. J.Biol.Chem., 299, 2023
|
|
7TBA
| Pentraxin - ligand complex | Descriptor: | C-reactive protein, CALCIUM ION, [3-(dibutylamino)propyl]phosphonic acid | Authors: | Shing, K.S.C.T, Morton, C.J, Parker, M.W. | Deposit date: | 2021-12-21 | Release date: | 2022-10-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein. Embo Mol Med, 15, 2023
|
|
7ZL1
| PTX3 Pentraxin Domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Pentraxin-related protein PTX3 | Authors: | Noone, D.P, Sharp, T.H. | Deposit date: | 2022-04-13 | Release date: | 2022-08-03 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7PK9
| C-reactive protein decamer at pH 7.5 | Descriptor: | C-reactive protein, CALCIUM ION | Authors: | Noone, D.P, Sharp, T.H. | Deposit date: | 2021-08-25 | Release date: | 2021-12-22 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein. Front Immunol, 12, 2021
|
|
7PKB
| C-reactive protein pentamer at pH 7.5 | Descriptor: | C-reactive protein, CALCIUM ION | Authors: | Noone, D.P, Sharp, T.H. | Deposit date: | 2021-08-25 | Release date: | 2021-12-22 | Last modified: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein. Front Immunol, 12, 2021
|
|
7PKG
| C-reactive protein pentamer at pH 5 | Descriptor: | C-reactive protein, CALCIUM ION | Authors: | Noone, D.P, Sharp, T.H. | Deposit date: | 2021-08-25 | Release date: | 2021-12-22 | Last modified: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein. Front Immunol, 12, 2021
|
|
7PKF
| C-reactive protein decamer at pH 5 | Descriptor: | C-reactive protein, CALCIUM ION | Authors: | Noone, D.P, Sharp, T.H. | Deposit date: | 2021-08-25 | Release date: | 2021-12-22 | Last modified: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein. Front Immunol, 12, 2021
|
|
7PKE
| C-reactive protein pentamer at pH 7.5 with phosphocholine ligand | Descriptor: | C-reactive protein, CALCIUM ION, PHOSPHOCHOLINE | Authors: | Noone, D.P, Sharp, T.H. | Deposit date: | 2021-08-25 | Release date: | 2021-12-22 | Last modified: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein. Front Immunol, 12, 2021
|
|
7PKD
| C-reactive protein decamer at pH 7.5 with phosphocholine ligand | Descriptor: | C-reactive protein, CALCIUM ION, PHOSPHOCHOLINE | Authors: | Noone, D.P, Sharp, T.H. | Deposit date: | 2021-08-25 | Release date: | 2021-12-22 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein. Front Immunol, 12, 2021
|
|
7PKH
| C-reactive protein decamer at pH 5 with phosphocholine ligand | Descriptor: | C-reactive protein, CALCIUM ION, PHOSPHOCHOLINE | Authors: | Noone, D.P, Sharp, T.H. | Deposit date: | 2021-08-25 | Release date: | 2021-12-22 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein. Front Immunol, 12, 2021
|
|
6YPE
| |
6V55
| Full extracellular region of zebrafish Gpr126/Adgrg6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G-protein coupled receptor G6, CALCIUM ION | Authors: | Leon, K, Arac, D. | Deposit date: | 2019-12-03 | Release date: | 2020-01-15 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structural basis for adhesion G protein-coupled receptor Gpr126 function. Nat Commun, 11, 2020
|
|
4PBP
| crystal structure of zebrafish short-chain pentraxin protein | Descriptor: | C-reactive protein, CALCIUM ION, GLYCEROL | Authors: | Chen, R, Qi, J.X, George, F.G, Xia, C. | Deposit date: | 2014-04-13 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.648 Å) | Cite: | Crystal structures for short-chain pentraxin from zebrafish demonstrate a cyclic trimer with new recognition and effector faces. J.Struct.Biol., 189, 2015
|
|
4PBO
| |
4AYU
| Structure of N-Acetyl-D-Proline bound to serum amyloid P component | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | Authors: | Hughes, P, Kolstoe, S.E, Wood, S.P. | Deposit date: | 2012-06-22 | Release date: | 2013-07-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc) Acta Crystallogr.,Sect.D, 70, 2014
|
|
4AVV
| Structure of CPHPC bound to Serum Amyloid P Component | Descriptor: | (2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxidanylidene-hexanoyl]pyrrolidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kolstoe, S.E, Jenvey, M.C, Wood, S.P. | Deposit date: | 2012-05-29 | Release date: | 2013-06-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc) Acta Crystallogr.,Sect.D, 70, 2014
|
|
4AVS
| |
4AVT
| Structure of CPHPC bound to Serum Amyloid P Component | Descriptor: | (2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxidanylidene-hexanoyl]pyrrolidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Kolstoe, S.E, Purvis, A, Wood, S.P. | Deposit date: | 2012-05-29 | Release date: | 2013-06-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc) Acta Crystallogr.,Sect.D, 70, 2014
|
|
3PVN
| Triclinic form of Human C-Reactive Protein in complex with Zinc | Descriptor: | C-reactive protein, CALCIUM ION, ZINC ION | Authors: | Guillon, C, Mavoungou Bigouagou, U, Jeannin, P, Delneste, Y, Gouet, P. | Deposit date: | 2010-12-07 | Release date: | 2012-01-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | A Staggered Decameric Assembly of Human C-Reactive Protein Stabilized by Zinc Ions Revealed by X-ray Crystallography. Protein Pept.Lett., 22, 2014
|
|
3PVO
| Monoclinic form of Human C-Reactive Protein | Descriptor: | C-Reactive Protein, CALCIUM ION | Authors: | Guillon, C, Mavoungou Bigouagou, U, Jeannin, P, Delneste, Y, Gouet, P. | Deposit date: | 2010-12-07 | Release date: | 2012-01-11 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Staggered Decameric Assembly of Human C-Reactive Protein Stabilized by Zinc Ions Revealed by X-ray Crystallography. Protein Pept.Lett., 22, 2014
|
|
3KQR
| The structure of serum amyloid p component bound to phosphoethanolamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ... | Authors: | Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B. | Deposit date: | 2009-11-17 | Release date: | 2010-12-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. J.Mol.Recognit., 24, 2011
|
|
3L2Y
| The structure of C-reactive protein bound to phosphoethanolamine | Descriptor: | C-reactive protein, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER | Authors: | Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B. | Deposit date: | 2009-12-15 | Release date: | 2010-12-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. J.Mol.Recognit., 24, 2011
|
|