PDB: 436 resultsInfo pagesStatus searchChemie searchBIRD

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4XC4	Insulin co-crystallizes in the presence of it beta-cell chaperone sulfatide Descriptor: CHLORIDE ION, Insulin, SODIUM ION, ... Authors: Bracey, A.W, Magis, A.T, Buschard, K, Osterbye, T, Bailey, K.M, Ostrov, D.A. Deposit date: 2014-12-17 Release date: 2015-02-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.499 Å) Cite: Insulin co-crystallizes in the presence of it beta-cell chaperone sulfatide To Be Published
1CPH	CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 Descriptor: 1,2-DICHLOROETHANE, INSULIN (PH 10), SODIUM ION Authors: Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. Deposit date: 1992-10-30 Release date: 1993-01-15 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
1DPH	CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 Descriptor: 1,2-DICHLOROETHANE, INSULIN A CHAIN (PH 11), INSULIN B CHAIN (PH 11), ... Authors: Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. Deposit date: 1992-10-30 Release date: 1993-01-15 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
5VIZ	X-Ray structure of Insulin Glargine Descriptor: Insulin, chain alpha, chain beta Authors: Reyes-Grajeda, J.P, Romero, A. Deposit date: 2017-04-17 Release date: 2017-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: X-Ray structure of Insulin Glargine To Be Published
5WDM	An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein Descriptor: Single-chain insulin analog Authors: Yee, V.C, Aldabbagh, K, Peng, Y. Deposit date: 2017-07-05 Release date: 2017-11-15 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.803 Å) Cite: An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein. J. Biol. Chem., 293, 2018
7NHU	Crystal structure of desB30 insulin produced by cell free protein synthesis Descriptor: Insulin Authors: Johansson, E. Deposit date: 2021-02-11 Release date: 2021-06-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Cell free protein synthesis versus yeast expression - A comparison using insulin as a model protein. Protein Expr.Purif., 186, 2021
5WBT	Solution Structure and Dynamics of an Ultra-Stable Single-Chain Insulin Analog STUDIES OF AN ENGINEERED MONOMER AND IMPLICATIONS FOR RECEPTOR BINDING Descriptor: Insulin Authors: Glidden, M.D, Yang, Y, Wickramasinghe, N.P, Weiss, M.A. Deposit date: 2017-06-29 Release date: 2017-11-15 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding. J. Biol. Chem., 293, 2018
7Z5L	Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and dimethyl sulfoxide (DMSO) Descriptor: GLYCEROL, Insulin A chain, Insulin B chain, ... Authors: van den Elsen, J.M.H, Wahid, A.A, Crennell, C. Deposit date: 2022-03-09 Release date: 2023-03-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling To Be Published
7Z5Q	Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and p-Hydroxyphenylpyruvate (HPP) Descriptor: Insulin, Insulin A chain, SULFATE ION Authors: van den Elsen, J.M.H, Wahid, A.A, Crennell, S.J. Deposit date: 2022-03-09 Release date: 2023-03-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling To Be Published
7INS	STRUCTURE OF PORCINE INSULIN COCRYSTALLIZED WITH CLUPEINE Z Descriptor: GENERAL PROTAMINE CHAIN, INSULIN (CHAIN A), INSULIN (CHAIN B), ... Authors: Balschmidt, P, Hansen, F.B, Dodson, E, Dodson, G, Korber, F. Deposit date: 1991-09-03 Release date: 1994-01-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of porcine insulin cocrystallized with clupeine Z. Acta Crystallogr.,Sect.B, 47, 1991
7JP3	Des-B29,B30-insulin Descriptor: CHLORIDE ION, Insulin B chain,Insulin A chain, PHENOL, ... Authors: Yoder, J, Weiss, M.A, DiMarchi, R, Zaykov, A. Deposit date: 2020-08-07 Release date: 2021-10-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Des-B29,B30-insulin To Be Published
4RXW	Crystal Structure of the cobalt human insulin derivative Descriptor: COBALT (II) ION, Insulin A chain, Insulin B chain Authors: Prugovecki, B, Ivetic, N, Matkovic-Calogovic, D. Deposit date: 2014-12-12 Release date: 2015-01-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Crystal Structure of the cobalt human insulin derivative TO BE PUBLISHED
4UNE	Human insulin B26Phe mutant crystal structure Descriptor: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION Authors: Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. Deposit date: 2014-05-28 Release date: 2014-10-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
4UNH	Human insulin B26Gly mutant crystal structure Descriptor: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION Authors: Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. Deposit date: 2014-05-28 Release date: 2014-10-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
8GSG	T3R3 form of Human insulin with single Zn Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Zhu, Z.L. Deposit date: 2022-09-06 Release date: 2023-03-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.05 Å) Cite: T3R3 insulin with single Zn To Be Published
4UNG	Human insulin B26Asn mutant crystal structure Descriptor: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION Authors: Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. Deposit date: 2014-05-28 Release date: 2014-10-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
8HSF	Insulin triple mutant INS-RQD Descriptor: Insulin A chain, Insulin B chain Authors: Kundapura, S.V, Rao, S.S, Kulal, A, Ramagopal, U.A. Deposit date: 2022-12-19 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Insulin triple mutant INS-RQD To Be Published
7ELJ	Prion Derived Tetrapeptide Stabilizes Thermolabile Insulin via Conformational Trapping Descriptor: IS1, Insulin A Chain, Insulin B chain Authors: Banerjee, N. Deposit date: 2021-04-11 Release date: 2021-04-28 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Prion-derived tetrapeptide stabilizes thermolabile insulin via conformational trapping. Iscience, 24, 2021
8HSK	Insulin single mutant INS-Q Descriptor: Insulin A chain, Insulin B chain, SULFATE ION Authors: Rao, S.S, Kundapura, S.V, Kulal, A, Ramagopal, U.A. Deposit date: 2022-12-19 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Insulin single mutant INS-Q To Be Published
8HGZ	Crystal structure of insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: DeMirci, H, Ayan, E. Deposit date: 2022-11-16 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Comparative Study of High-Resolution LysB29(N epsilon-myristoyl) des(B30) Insulin Structures Display Novel Dynamic Causal Interrelations in Monomeric-Dimeric Motions Crystals, 13, 2023
5L3M	D11 bound [S39_PQ]-IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3N	D11 bound [N29, S39_PQ]-IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3L	D11 bound IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5LIS	Insulin solved by Native SAD from a dataset collected in one second Descriptor: Insulin Authors: Casanas, A, Finke, A, Wang, M. Deposit date: 2016-07-15 Release date: 2016-08-03 Last modified: 2016-09-28 Method: X-RAY DIFFRACTION (2.293 Å) Cite: EIGER detector: application in macromolecular crystallography. Acta Crystallogr D Struct Biol, 72, 2016
6U46	Solution Structure of a Heat-Resistant Long-Acting Insulin Analog Descriptor: Insulin Authors: Yang, Y, Weiss, M.A. Deposit date: 2019-08-23 Release date: 2020-08-26 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Solution Structure of a Heat-Resistant Long-Acting Insulin Analog To Be Published

 

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