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8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
Descriptor: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
Authors:Kachariya, N, Sattler, M, Keil, P, Strasser, K.
Deposit date:2022-10-04
Release date:2022-11-09
Last modified:2024-06-19
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
9IZM
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BU of 9izm by Molmil
Cryo-EM structure of CasLambda2-crRNA binary complex
Descriptor: Cas Lambda2, MAGNESIUM ION, RNA (58-MER)
Authors:Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
Deposit date:2024-08-01
Release date:2025-06-11
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structural basis for target DNA cleavage and guide RNA processing by CRISPR-Cas lambda 2.
Commun Biol, 8, 2025
9LMF
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BU of 9lmf by Molmil
Streptococcus agalactiae GOLLD RNA 3' domain decamer
Descriptor: RNA (700-MER)
Authors:Xie, J, Peng, X, Wang, L, Su, Z.
Deposit date:2025-01-18
Release date:2025-03-19
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Cryo-EM reveals mechanisms of natural RNA multivalency.
Science, 388, 2025
5XJ2
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BU of 5xj2 by Molmil
Structure of spRlmCD with U747 RNA
Descriptor: RNA (5'-R(*GP*GP*CP*AP*CP*GP*UP*GP*CP*U)-3'), S-ADENOSYL-L-HOMOCYSTEINE, Uncharacterized RNA methyltransferase SP_1029, ...
Authors:Jiang, Y, Gong, Q.
Deposit date:2017-04-28
Release date:2017-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD
PLoS ONE, 12, 2017
4WJ3
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BU of 4wj3 by Molmil
Crystal structure of the asparagine transamidosome from Pseudomonas aeruginosa
Descriptor: 76mer-tRNA, Aspartate--tRNA(Asp/Asn) ligase, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, ...
Authors:Suzuki, T, Nakamura, A, Kato, K, Tanaka, I, Yao, M.
Deposit date:2014-09-29
Release date:2014-12-31
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.705 Å)
Cite:Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis
Proc.Natl.Acad.Sci.USA, 112, 2015
4V74
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BU of 4v74 by Molmil
70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre5b)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
8HKE
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BU of 8hke by Molmil
dsRNA transporter
Descriptor: RNA (37-MER), Systemic RNA interference defective protein 1, ZINC ION
Authors:Jiang, D.H, Zhang, J.T.
Deposit date:2022-11-25
Release date:2023-11-29
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural insights into double-stranded RNA recognition and transport by SID-1.
Nat.Struct.Mol.Biol., 31, 2024
6L5N
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BU of 6l5n by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 at post-unwound state
Descriptor: MAGNESIUM ION, Nucleolar RNA helicase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
Deposit date:2019-10-24
Release date:2020-06-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.242 Å)
Cite:Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
6L1W
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BU of 6l1w by Molmil
Zinc-finger Antiviral Protein (ZAP) bound to RNA
Descriptor: RNA (5'-R(*CP*GP*UP*CP*GP*U)-3'), ZINC ION, Zinc finger CCCH-type antiviral protein 1
Authors:Luo, X, Wang, X, Gao, Y, Zhu, J, Liu, S, Gao, G, Gao, P.
Deposit date:2019-09-30
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein.
Cell Rep, 30, 2020
4V84
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BU of 4v84 by Molmil
Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome.
Descriptor: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S.
Deposit date:2010-12-13
Release date:2014-07-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 108, 2011
9JC7
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BU of 9jc7 by Molmil
Crystal structure of alanyl-tRNA synthetase in complex with ATP and L-alanine
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, ALANINE, ...
Authors:Son, S.Y, Cha, S.S.
Deposit date:2024-08-28
Release date:2025-06-18
Last modified:2025-06-25
Method:X-RAY DIFFRACTION (1.90000343 Å)
Cite:Unlocking the serine mischarging paradox and inhibiting lactyltransferase activity of AlaRS by a single-point mutation.
Nucleic Acids Res., 53, 2025
9JDN
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BU of 9jdn by Molmil
Crystal structure of alanyl-tRNA synthetase L219M mutant in complex with ATP and L-alanine
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, ALANINE, ...
Authors:Son, S.Y, Cha, S.S.
Deposit date:2024-08-31
Release date:2025-06-18
Last modified:2025-06-25
Method:X-RAY DIFFRACTION (2.18006659 Å)
Cite:Unlocking the serine mischarging paradox and inhibiting lactyltransferase activity of AlaRS by a single-point mutation.
Nucleic Acids Res., 53, 2025
6YSS
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BU of 6yss by Molmil
Structure of the P+9 ArfB-ribosome complex in the post-hydrolysis state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2025-03-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
6YSU
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BU of 6ysu by Molmil
Structure of the P+0 ArfB-ribosome complex in the post-hydrolysis state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2025-03-12
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
4V92
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BU of 4v92 by Molmil
Kluyveromyces lactis 80S ribosome in complex with CrPV-IRES
Descriptor: 18S RRNA, ES1, ES10, ...
Authors:Fernandez, I.S, Bai, X, Scheres, S.H.W, Ramakrishnan, V.
Deposit date:2014-03-21
Release date:2014-07-09
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
4W5Q
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BU of 4w5q by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5R
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BU of 4w5r by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8 (Long Target)
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5T
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BU of 4w5t by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-7
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5O
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BU of 4w5o by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-9
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
8CTH
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BU of 8cth by Molmil
Cryo-EM structure of human METTL1-WDR4-tRNA(Phe) complex
Descriptor: Phe-tRNA, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(7)-)-methyltransferase, ...
Authors:Li, J, Wang, L, Fontana, P, Hunkeler, M, Roy-Burman, S.S, Wu, H, Fishcer, E.S, Gregory, R.I.
Deposit date:2022-05-14
Release date:2022-12-07
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.
Nature, 613, 2023
8D9K
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BU of 8d9k by Molmil
CryoEM structure of human METTL1-WDR4 in complex with Lys-tRNA
Descriptor: RNA (65-MER), tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4
Authors:Ruiz-Arroyo, V.M, Nam, Y.
Deposit date:2022-06-10
Release date:2023-01-11
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structures and mechanisms of tRNA methylation by METTL1-WDR4.
Nature, 613, 2023
5FLM
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BU of 5flm by Molmil
Structure of transcribing mammalian RNA polymerase II
Descriptor: DNA, DNA-RNA ELONGATION SCAFFOLD, DNA-DIRECTED RNA POLYMERASE, ...
Authors:Bernecky, C, Herzog, F, Baumeister, W, Plitzko, J.M, Cramer, P.
Deposit date:2015-10-26
Release date:2016-01-20
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of Transcribing Mammalian RNA Polymerase II
Nature, 529, 2016
4D0Y
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BU of 4d0y by Molmil
Crystal structure of DacB from Streptococcus pneumoniae D39
Descriptor: DACB, PHOSPHATE ION, ZINC ION
Authors:Gutierrez-Fernandez, J, Hermoso, J.A.
Deposit date:2014-04-30
Release date:2014-08-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Pneumococcal L,D-Carboxypeptidase Dacb and Pathophysiological Effects of Disabled Cell Wall Hydrolases Daca and Dacb.
Mol.Microbiol., 93, 2014
4XWW
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BU of 4xww by Molmil
Crystal structure of RNase J complexed with RNA
Descriptor: DR2417, GLYCEROL, MANGANESE (II) ION, ...
Authors:Lu, M, Zhang, H, Xu, Q, Hua, Y, Zhao, Y.
Deposit date:2015-01-29
Release date:2015-12-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
Nucleic Acids Res., 43, 2015
3E9O
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BU of 3e9o by Molmil
Crystal Structure of Yeast Prp8, Residues 1836-2092
Descriptor: Pre-mRNA-splicing factor 8
Authors:Pena, V, Rozov, A, Wahl, M.C.
Deposit date:2008-08-22
Release date:2008-10-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of an RNase H domain at the heart of the spliceosome.
Embo J., 27, 2008

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