6KLD
 
 | | Structure of apo Machupo virus polymerase | | Descriptor: | MANGANESE (II) ION, RNA-directed RNA polymerase L, ZINC ION | | Authors: | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | | Deposit date: | 2019-07-30 | | Release date: | 2020-03-18 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Structural insight into arenavirus replication machinery.
Nature, 579, 2020
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7RDQ
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7OM9
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5A2V
 | | Crystal structure of mtPAP in Apo form | | Descriptor: | CHLORIDE ION, MITOCHONDRIAL PROTEIN | | Authors: | Lapkouski, M, Hallberg, B.M. | | Deposit date: | 2015-05-26 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Nucleic Acids Res., 43, 2015
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5A2Z
 | | Crystal structure of mtPAP in complex with GTP | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MITOCHONDRIAL PROTEIN | | Authors: | Lapkouski, M, Hallberg, B.M. | | Deposit date: | 2015-05-26 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Nucleic Acids Res., 43, 2015
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5A2W
 | | Crystal structure of mtPAP in complex with ATPgammaS | | Descriptor: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, MITOCHONDRIAL PROTEIN, ... | | Authors: | Lapkouski, M, Hallberg, B.M. | | Deposit date: | 2015-05-26 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Nucleic Acids Res., 43, 2015
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7VPD
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5A2X
 | | Crystal structure of mtPAP in complex with CTP | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MITOCHONDRIAL PROTEIN | | Authors: | Lapkouski, M, Hallberg, B.M. | | Deposit date: | 2015-05-26 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Nucleic Acids Res., 43, 2015
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5A2Y
 | | Crystal structure of mtPAP in complex with UTP | | Descriptor: | MAGNESIUM ION, MITOCHONDRIAL PROTEIN, URIDINE 5'-TRIPHOSPHATE | | Authors: | Lapkouski, M, Hallberg, B.M. | | Deposit date: | 2015-05-26 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Nucleic Acids Res., 43, 2015
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5A30
 | | Crystal structure of mtPAP N472D mutant in complex with ATPgammaS | | Descriptor: | MAGNESIUM ION, MITOCHONDRIAL PROTEIN, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | Authors: | Lapkouski, M, Hallberg, B.M. | | Deposit date: | 2015-05-26 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Nucleic Acids Res., 43, 2015
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7ORI
 | | La Crosse virus polymerase at replication late-elongation stage | | Descriptor: | La Crosse virus polymerase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | | Authors: | Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. | | Deposit date: | 2021-06-06 | | Release date: | 2022-02-16 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022
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6LBJ
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6LBK
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2GA9
 | | Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound ATP-gamma-S | | Descriptor: | CALCIUM ION, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Moure, C.M, Bowman, B.R, Gershon, P.D, Quiocho, F.A. | | Deposit date: | 2006-03-08 | | Release date: | 2006-05-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity.
Mol.Cell, 22, 2006
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7EH0
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2GAF
 | | Crystal Structure of the Vaccinia Polyadenylate Polymerase Heterodimer (apo form) | | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit | | Authors: | Moure, C.M, Bowman, B.R, Gershon, P.D, Quiocho, F.A. | | Deposit date: | 2006-03-08 | | Release date: | 2006-05-16 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity.
Mol.Cell, 22, 2006
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7X76
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7X75
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7CKM
 | | Structure of Machupo virus polymerase bound to Z matrix protein (monomeric complex) | | Descriptor: | MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... | | Authors: | Xu, X, Peng, R, Peng, Q, Shi, Y. | | Deposit date: | 2020-07-17 | | Release date: | 2021-05-05 | | Last modified: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals
Nat Microbiol, 6, 2021
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7CKL
 | | Structure of Lassa virus polymerase bound to Z matrix protein | | Descriptor: | MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... | | Authors: | Xu, X, Peng, R, Peng, Q, Shi, Y. | | Deposit date: | 2020-07-17 | | Release date: | 2021-05-05 | | Last modified: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.88 Å) | | Cite: | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals
Nat Microbiol, 6, 2021
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7ORO
 | | La Crosse virus polymerase at replication early-elongation stage | | Descriptor: | La Crosse virus polymerase, MAGNESIUM ION, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*C)-3'), ... | | Authors: | Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. | | Deposit date: | 2021-06-06 | | Release date: | 2022-02-16 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022
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8P0G
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8P0B
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8P0U
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1FA0
 | | STRUCTURE OF YEAST POLY(A) POLYMERASE BOUND TO MANGANATE AND 3'-DATP | | Descriptor: | 3'-DEOXYADENOSINE, 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | | Authors: | Bard, J, Zhelkovsky, A.M, Helmling, S, Moore, C.L, Bohm, A. | | Deposit date: | 2000-07-11 | | Release date: | 2000-08-30 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of yeast poly(A) polymerase alone and in complex with 3'-dATP.
Science, 289, 2000
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