3BJK
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![BU of 3bjk by Molmil](/molmil-images/mine/3bjk) | Crystal structure of HI0827, a hexameric broad specificity acyl-coenzyme A thioesterase: The Asp44Ala mutant enzyme | Descriptor: | 1,2-ETHANEDIOL, Acyl-CoA thioester hydrolase HI0827, CITRIC ACID | Authors: | Willis, M.A, Herzberg, O, Structure 2 Function Project (S2F) | Deposit date: | 2007-12-04 | Release date: | 2008-02-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of YciA from Haemophilus influenzae (HI0827), a Hexameric Broad Specificity Acyl-Coenzyme A Thioesterase. Biochemistry, 47, 2008
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3B3B
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3BDG
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1Y0X
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![BU of 1y0x by Molmil](/molmil-images/mine/1y0x) | Thyroxine-Thyroid Hormone Receptor Interactions | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, CACODYLATE ION, Thyroid hormone receptor beta-1 | Authors: | Sandler, B, Webb, P, Apriletti, J.W, Huber, B.R, Togashi, M, Cunha Lima, S.T, Juric, S, Nilsson, S, Wagner, R, Fletterick, R.J, Baxter, J.D. | Deposit date: | 2004-11-16 | Release date: | 2004-12-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Thyroxine-thyroid hormone receptor interactions. J.Biol.Chem., 279, 2004
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8B8E
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![BU of 8b8e by Molmil](/molmil-images/mine/8b8e) | Wild-type GH11 from Blastobotrys mokoenaii | Descriptor: | 1,2-ETHANEDIOL, BmGH11, DI(HYDROXYETHYL)ETHER, ... | Authors: | Coleman, T, Ravn, J.L, Larsbrink, J. | Deposit date: | 2022-10-04 | Release date: | 2023-05-17 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Yeasts Have Evolved Divergent Enzyme Strategies To Deconstruct and Metabolize Xylan. Microbiol Spectr, 11, 2023
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3B63
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![BU of 3b63 by Molmil](/molmil-images/mine/3b63) | Actin filament model in the extended form of acromsomal bundle in the Limulus sperm | Descriptor: | Actin | Authors: | Cong, Y, Topf, M, Sali, A, Matsudaira, P, Dougherty, M, Chiu, W, Schmid, M.F. | Deposit date: | 2007-10-26 | Release date: | 2008-11-18 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Crystallographic conformers of actin in a biologically active bundle of filaments. J.Mol.Biol., 375, 2008
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1Y4C
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![BU of 1y4c by Molmil](/molmil-images/mine/1y4c) | Designed Helical Protein fusion MBP | Descriptor: | Maltose binding protein fused with designed helical protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | LaPorte, S.L, Forsyth, C.M, Cunningham, B.C, Miercke, L.J, Akhavan, D, Stroud, R.M. | Deposit date: | 2004-11-30 | Release date: | 2005-02-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | De novo design of an IL-4 antagonist and its structure at 1.9 A. Proc.Natl.Acad.Sci.Usa, 102, 2005
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3BI4
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![BU of 3bi4 by Molmil](/molmil-images/mine/3bi4) | Crystal structures of fms1 in complex with its inhibitors | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, N-[(1E,2Z)-but-2-en-1-ylidene]-N'-[(2E)-but-2-en-1-ylidene]butane-1,4-diamine, Polyamine oxidase FMS1 | Authors: | Huang, Q, Hao, Q. | Deposit date: | 2007-11-29 | Release date: | 2008-01-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of fms1 in complex with its inhibitors To be Published
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3BDF
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3BAB
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![BU of 3bab by Molmil](/molmil-images/mine/3bab) | Structural Basis for the Inhibition of Bacterial NAD+ Dependent DNA Ligase | Descriptor: | 7-amino-2-tert-butyl-4-(4-pyrimidin-2-ylpiperazin-1-yl)pyrido[2,3-d]pyrimidine-6-carboxamide, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, ... | Authors: | Pinko, C. | Deposit date: | 2007-11-07 | Release date: | 2008-11-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for the Inhibition of Bacterial NAD+ Dependent DNA Ligase To be Published
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1YHF
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![BU of 1yhf by Molmil](/molmil-images/mine/1yhf) | Crystal Structure of Conserved SPY1581 Protein of Unknown Function from Streptococcus pyogenes | Descriptor: | hypothetical protein SPy1581 | Authors: | Osipiuk, J, Lezondra, L, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-01-07 | Release date: | 2005-02-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray crystal structure of conserved hypothetical SPy1581 protein from Streptococcus pyogenes. To be Published
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1YHL
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![BU of 1yhl by Molmil](/molmil-images/mine/1yhl) | Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2 | Descriptor: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M. | Deposit date: | 2005-01-09 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design. Proteins, 62, 2005
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1Y3G
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![BU of 1y3g by Molmil](/molmil-images/mine/1y3g) | Crystal Structure of a Silanediol Protease Inhibitor Bound to Thermolysin | Descriptor: | (2S)-2-{[(AMINOMETHYL)(DIHYDROXY)SILYL]METHYL}-4-METHYLPENTANAL, 3-PHENYLPROPANAL, CALCIUM ION, ... | Authors: | Juers, D.H, Kim, J, Matthews, B.W, Sieburth, S.M. | Deposit date: | 2004-11-24 | Release date: | 2006-01-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Analysis of Silanediols as Transition-State-Analogue Inhibitors of the Benchmark Metalloprotease Thermolysin(,). Biochemistry, 44, 2005
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1YHG
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6UWF
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![BU of 6uwf by Molmil](/molmil-images/mine/6uwf) | GltPh in complex with L-aspartate and sodium ions in outward-facing state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Wang, X, Boudker, O. | Deposit date: | 2019-11-05 | Release date: | 2020-06-03 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Use of paramagnetic 19 F NMR to monitor domain movement in a glutamate transporter homolog. Nat.Chem.Biol., 16, 2020
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1ZF9
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![BU of 1zf9 by Molmil](/molmil-images/mine/1zf9) | GGG Duplex A-DNA | Descriptor: | 5'-D(*CP*CP*CP*CP*CP*GP*GP*GP*GP*G)-3', SODIUM ION | Authors: | Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S. | Deposit date: | 2005-04-20 | Release date: | 2005-05-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | How sequence defines structure: a crystallographic map of DNA structure and conformation. Proc.Natl.Acad.Sci.Usa, 102, 2005
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6UZ8
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![BU of 6uz8 by Molmil](/molmil-images/mine/6uz8) | Cryo-EM structure of human TRPC6 in complex with agonist AM-0883 | Descriptor: | (5-chloro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)[(2R)-2,3-dihydro-1,4-benzodioxin-2-yl]methanone, 2-[[(2~{S})-2-decanoyloxy-3-dodecanoyloxy-propoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Bai, Y, Yu, X, Huang, X, Chen, H. | Deposit date: | 2019-11-14 | Release date: | 2020-03-18 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structural basis for pharmacological modulation of the TRPC6 channel. Elife, 9, 2020
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1ZFM
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![BU of 1zfm by Molmil](/molmil-images/mine/1zfm) | AGC Duplex B-DNA | Descriptor: | 5'-D(*CP*CP*GP*CP*TP*AP*GP*CP*GP*G)-3' | Authors: | Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S. | Deposit date: | 2005-04-20 | Release date: | 2005-05-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | How sequence defines structure: a crystallographic map of DNA structure and conformation. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1ZG1
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![BU of 1zg1 by Molmil](/molmil-images/mine/1zg1) | NarL complexed to nirB promoter non-palindromic tail-to-tail DNA site | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*CP*CP*AP*TP*TP*AP*AP*GP*GP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*TP*AP*CP*TP*CP*CP*TP*TP*AP*AP*TP*GP*GP*GP*TP*AP*CP*G)-3', Nitrate/nitrite response regulator protein narL, ... | Authors: | Maris, A.E, Kaczor-Grzeskowiak, M, Ma, Z, Kopka, M.L, Gunsalus, R.P, Dickerson, R.E. | Deposit date: | 2005-04-20 | Release date: | 2005-11-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Primary and Secondary Modes of DNA Recognition by the NarL Two-Component Response Regulator. Biochemistry, 44, 2005
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1ZP8
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![BU of 1zp8 by Molmil](/molmil-images/mine/1zp8) | HIV Protease with inhibitor AB-2 | Descriptor: | Pol polyprotein, [1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL (1R,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YLCARBAMATE | Authors: | Brik, A, Alexandratos, J.N, Elder, J.H, Olson, A.J, Wlodawer, A, Goodsell, D.S, Wong, C.H. | Deposit date: | 2005-05-16 | Release date: | 2005-06-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors. Chembiochem, 6, 2005
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3B1L
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3B5X
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![BU of 3b5x by Molmil](/molmil-images/mine/3b5x) | Crystal Structure of MsbA from Vibrio cholerae | Descriptor: | Lipid A export ATP-binding/permease protein msbA | Authors: | Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G. | Deposit date: | 2007-10-26 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3B35
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![BU of 3b35 by Molmil](/molmil-images/mine/3b35) | Crystal structure of the M180A mutant of the aminopeptidase from Vibrio proteolyticus | Descriptor: | Bacterial leucyl aminopeptidase, SODIUM ION, THIOCYANATE ION, ... | Authors: | Ataie, N.J, Hoang, Q.Q, Petsko, G.A, Ringe, D. | Deposit date: | 2007-10-19 | Release date: | 2007-11-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus. Biochemistry, 47, 2008
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3B49
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3B9L
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![BU of 3b9l by Molmil](/molmil-images/mine/3b9l) | Human serum albumin complexed with myristate and AZT | Descriptor: | 3'-azido-3'-deoxythymidine, MYRISTIC ACID, Serum albumin | Authors: | Zhu, L, Yang, F, Chen, L, Meehan, E.J, Huang, M. | Deposit date: | 2007-11-05 | Release date: | 2008-05-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography J.Struct.Biol., 162, 2008
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