3AMT
 
 | | Crystal structure of the TiaS-tRNA(Ile2)-ATP complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Putative uncharacterized protein, RNA (78-MER) | | Authors: | Numata, T, Osawa, T. | | Deposit date: | 2010-08-23 | | Release date: | 2011-10-12 | | Last modified: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis of tRNA agmatinylation essential for AUA codon decoding
Nat.Struct.Mol.Biol., 18, 2011
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3AMU
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1J2B
 | | Crystal Structure Of Archaeosine tRNA-Guanine Transglycosylase Complexed With lambda-form tRNA(Val) | | Descriptor: | Archaeosine tRNA-guanine transglycosylase, MAGNESIUM ION, ZINC ION, ... | | Authors: | Ishitani, R, Nureki, O, Nameki, N, Okada, N, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2002-12-29 | | Release date: | 2003-05-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Alternative Tertiary Structure of tRNA for Recognition by a Posttranscriptional Modification Enzyme
Cell(Cambridge,Mass.), 113, 2003
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6N5P
 | | Structure of Human pir-miRNA-340 Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | | Deposit date: | 2018-11-22 | | Release date: | 2019-11-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.991 Å) | | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography
To Be Published
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2GIA
 | | Crystal structures of trypanosoma bruciei MRP1/MRP2 | | Descriptor: | ACETIC ACID, mitochondrial RNA-binding protein 1, mitochondrial RNA-binding protein 2 | | Authors: | Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J. | | Deposit date: | 2006-03-28 | | Release date: | 2006-09-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism.
Cell(Cambridge,Mass.), 126, 2006
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1FYJ
 | | SOLUTION STRUCTURE OF MULTI-FUNCTIONAL PEPTIDE MOTIF-1 PRESENT IN HUMAN GLUTAMYL-PROLYL TRNA SYNTHETASE (EPRS). | | Descriptor: | MULTIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE | | Authors: | Jeong, E.-J, Hwang, G.-S, Kim, K.H, Kim, M.J, Kim, S, Kim, K.-S. | | Deposit date: | 2000-10-02 | | Release date: | 2001-03-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural analysis of multifunctional peptide motifs in human bifunctional tRNA synthetase: identification of RNA-binding residues and functional implications for tandem repeats.
Biochemistry, 39, 2000
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7EZW
 | | Cyclic Peptide that Interacts with the eIF4E Capped-mRNA Binding Site | | Descriptor: | ALA-CYS-GLU-MET-GLY-PHE-PHE-GLN-ASP-CYS-GLY, Eukaryotic translation initiation factor 4E, SODIUM ION | | Authors: | Brown, C.J, Ng, S, Frosi, Y. | | Deposit date: | 2021-06-02 | | Release date: | 2022-06-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Development of a novel peptide aptamer that interacts with the eIF4E capped-mRNA binding site using peptide epitope linker evolution (PELE).
Rsc Chem Biol, 3, 2022
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1JWC
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1GTN
 | | Structure of the trp RNA-binding attenuation protein (TRAP) bound to an RNA molecule containing 11 GAGCC repeats | | Descriptor: | (GAGCC)11G 56-NUCLEOTIDE RNA, TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN | | Authors: | Hopcroft, N.H, Wendt, A.L, Gollnick, P, Antson, A.A. | | Deposit date: | 2002-01-16 | | Release date: | 2002-04-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Specificity of Trap-RNA Interactions: Crystal Structures of Two Complexes with Different RNA Sequences
Acta Crystallogr.,Sect.D, 58, 2002
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1JU7
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6L6V
 | | SPO1 Gp44 N-terminal region (1-55) | | Descriptor: | E3 protein | | Authors: | Liu, B, Wang, Z. | | Deposit date: | 2019-10-29 | | Release date: | 2021-05-05 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | A Bacteriophage DNA Mimic Protein Employs a Non-specific Strategy to Inhibit the Bacterial RNA Polymerase.
Front Microbiol, 12, 2021
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1SLO
 | | FIRST STEM LOOP OF THE SL1 RNA FROM CAENORHABDITIS ELEGANS, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | RNA (5'-R(*UP*UP*AP*CP*CP*CP*AP*AP*GP*UP*UP*UP*GP*AP*GP*GP*UP*AP*A)-3') | | Authors: | Greenbaum, N.L, Radhakrishnan, I, Patel, D.J, Hirsh, D. | | Deposit date: | 1996-05-24 | | Release date: | 1996-12-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the donor site of a trans-splicing RNA.
Structure, 4, 1996
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1SLP
 | | FIRST STEM LOOP OF THE SL1 RNA FROM CAENORHABDITIS ELEGANS, NMR, 16 STRUCTURES | | Descriptor: | RNA (5'-R(*UP*UP*AP*CP*CP*CP*AP*AP*GP*UP*UP*UP*GP*AP*GP*GP*UP*AP*A)-3') | | Authors: | Greenbaum, N.L, Radhakrishnan, I, Patel, D.J, Hirsh, D. | | Deposit date: | 1996-05-24 | | Release date: | 1997-04-21 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the donor site of a trans-splicing RNA.
Structure, 4, 1996
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1FQZ
 | | NMR VALIDATED MODEL OF DOMAIN IIID OF HEPATITIS C VIRUS INTERNAL RIBOSOME ENTRY SITE | | Descriptor: | HEPATITIS C VIRUS IRES DOMAIN IIID | | Authors: | Klinck, R, Westhof, E, Walker, S, Afshar, M, Collier, A, Aboul-ela, F. | | Deposit date: | 2000-09-07 | | Release date: | 2001-01-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A potential RNA drug target in the hepatitis C virus internal ribosomal entry site.
RNA, 6, 2000
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8PE1
 | | Crystal structure of Gel4 in complex with Nanobody 4 | | Descriptor: | 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 4, ... | | Authors: | Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. | | Deposit date: | 2023-06-13 | | Release date: | 2024-06-19 | | Last modified: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases.
Angew.Chem.Int.Ed.Engl., 2024
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8PE2
 | | Crystal structure of Gel4 in complex with Nanobody 3 | | Descriptor: | 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 3, ... | | Authors: | Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. | | Deposit date: | 2023-06-13 | | Release date: | 2024-06-19 | | Last modified: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases.
Angew.Chem.Int.Ed.Engl., 2024
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2F4V
 | | 30S ribosome + designer antibiotic | | Descriptor: | (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, (2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE, 16S ribosomal RNA, ... | | Authors: | Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S. | | Deposit date: | 2005-11-24 | | Release date: | 2006-07-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site
Chem.Biol., 13, 2006
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6UP0
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5UX0
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4Q4Z
 | | Thermus thermophilus RNA polymerase de novo transcription initiation complex | | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ADENOSINE-5'-TRIPHOSPHATE, DNA (25-MER), ... | | Authors: | Murakami, K.S. | | Deposit date: | 2014-04-15 | | Release date: | 2014-07-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme.
J.Biol.Chem., 289, 2014
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1TN2
 | | CRYSTALLOGRAPHIC AND BIOCHEMICAL INVESTIGATION OF THE LEAD(II)-CATALYZED HYDROLYSIS OF YEAST PHENYLALANINE T-RNA | | Descriptor: | LEAD (II) ION, MAGNESIUM ION, SPERMINE, ... | | Authors: | Brown, R.S, Dewan, J.C, Klug, A. | | Deposit date: | 1986-08-22 | | Release date: | 1986-10-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA.
Biochemistry, 24, 1985
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4Q5S
 | | Thermus thermophilus RNA polymerase initially transcribing complex containing 6-mer RNA | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*GP*CP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3'), ... | | Authors: | Murakami, K.S. | | Deposit date: | 2014-04-17 | | Release date: | 2014-07-09 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme.
J.Biol.Chem., 289, 2014
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2JQ7
 | | Model for thiostrepton binding to the ribosomal L11-RNA | | Descriptor: | 50S RIBOSOMAL PROTEIN L11, RIBOSOMAL RNA, THIOSTREPTON | | Authors: | Jonker, H.R.A, Ilin, S, Grimm, S.K, Woehnert, J, Schwalbe, H. | | Deposit date: | 2007-05-30 | | Release date: | 2007-07-03 | | Last modified: | 2021-08-18 | | Method: | SOLUTION NMR | | Cite: | L11 Domain Rearrangement Upon Binding to RNA and Thiostrepton Studied by NMR Spectroscopy
Nucleic Acids Res., 35, 2007
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7EU0
 | | The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex | | Descriptor: | DNA (33-MER), DNA (5'-D(*CP*TP*GP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase IV subunit 1, ... | | Authors: | Fang, C.L, Wu, X.X, Huang, K, Zhang, Y. | | Deposit date: | 2021-05-15 | | Release date: | 2021-12-29 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA.
Science, 374, 2021
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7EU1
 | | The cryo-EM structure of A. thaliana Pol IV-RDR2 holoenzyme | | Descriptor: | DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerases II and IV subunit 5A, DNA-directed RNA polymerases II, ... | | Authors: | Fang, C.L, Wu, X.X, Huang, K, Zhang, Y. | | Deposit date: | 2021-05-15 | | Release date: | 2021-12-29 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA.
Science, 374, 2021
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