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5SL7	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z1186029914 Descriptor: (3R)-1-(2-fluorophenyl)-3-(methylamino)pyrrolidin-2-one, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.841 Å) Cite: PanDDA analysis group deposition To Be Published
5SLI	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z1003146540 Descriptor: 2-(difluoromethoxy)benzene-1-sulfonamide, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: PanDDA analysis group deposition To Be Published
5SLO	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z56983806 Descriptor: 1-methyl-N-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.829 Å) Cite: PanDDA analysis group deposition To Be Published
5SLR	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z2073741691 Descriptor: 2-(difluoromethoxy)-1-[(2R,6S)-2,6-dimethylmorpholin-4-yl]ethan-1-one, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.86 Å) Cite: PanDDA analysis group deposition To Be Published
5SM3	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z943693514 Descriptor: PHOSPHATE ION, Proofreading exoribonuclease nsp14, ZINC ION, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.198 Å) Cite: PanDDA analysis group deposition To Be Published
5SM6	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z1899842917 Descriptor: 3-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-5-methyl-1,3,4-thiadiazol-2(3H)-one, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.29 Å) Cite: PanDDA analysis group deposition To Be Published
5SMI	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z71580604 Descriptor: (2S)-N-(5-methylpyridin-2-yl)oxolane-2-carboxamide, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.08 Å) Cite: PanDDA analysis group deposition To Be Published
5SMK	PanDDA analysis group deposition of ground-state model of SARS-CoV-2 NSP14 Descriptor: PHOSPHATE ION, Proofreading exoribonuclease nsp14, ZINC ION Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-08 Release date: 2022-03-23 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.65 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
5SCA	Structure of liver pyruvate kinase in complex with anthraquinone derivative 36 Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, N-[(3R)-1-(3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonyl)piperidine-3-carbonyl]-L-aspartic acid, ... Authors: Lulla, A, Foller, A, Nain-Perez, A, Grotli, M, Brear, P, Hyvonen, M. Deposit date: 2021-12-01 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.918 Å) Cite: Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase. Eur.J.Med.Chem., 234, 2022
5SL8	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z2856434762 Descriptor: N,N-dimethylpyridin-4-amine, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.07 Å) Cite: PanDDA analysis group deposition To Be Published
5SLN	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z57299529 Descriptor: PHOSPHATE ION, Proofreading exoribonuclease nsp14, ZINC ION, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.208 Å) Cite: PanDDA analysis group deposition To Be Published
5SM2	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z3006151474 Descriptor: (5S)-5-(difluoromethoxy)pyridin-2(5H)-one, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.781 Å) Cite: PanDDA analysis group deposition To Be Published
5SMH	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NSP14 in complex with Z2856434938 Descriptor: 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine, PHOSPHATE ION, Proofreading exoribonuclease nsp14, ... Authors: Imprachim, N, Yosaatmadja, Y, von-Delft, F, Bountra, C, Gileadi, O, Newman, J.A. Deposit date: 2022-03-03 Release date: 2022-03-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.64 Å) Cite: PanDDA analysis group deposition To Be Published
8Y88	Structure of HCoV-HKU1C spike in the functionally anchored-2up conformation with 2TMPRSS2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Method: ELECTRON MICROSCOPY (3.03 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
9ICE	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND CUCL2 (0.1 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9ICA	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SOAKED IN THE PRESENCE OF DATP(ALPHA)S AND MNCL2 Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1995-12-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9BA4	Full-length cross-linked Contactin 2 (CNTN2) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2 Authors: Liu, J.L, Fan, S.F, Ren, G.R, Rudenko, G.R. Deposit date: 2024-04-03 Release date: 2024-07-17 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Molecular mechanism of contactin 2 homophilic interaction. Structure, 2024
9F8X	Low-dose structure of Marinobacter nauticus nitrous oxide reductase Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... Authors: Einsle, O, Pomowski, A. Deposit date: 2024-05-07 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (1.498 Å) Cite: Revisiting the metal sites of nitrous oxide reductase in a low-dose structure from Marinobacter nauticus. J.Biol.Inorg.Chem., 29, 2024
8Y2H	GK tetramer of AtP5CS1 filament with adjacent hooks, reaction state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Delta-1-pyrroline-5-carboxylate synthase A Authors: Zhang, T, Guo, C.J, Liu, J.L. Deposit date: 2024-01-26 Release date: 2024-06-05 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Dynamic Arabidopsis P5CS filament facilitates substrate channelling. Nat.Plants, 10, 2024
9ICR	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DCTP AND MNCL2 Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-01-04 Release date: 1996-01-04 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3 Å) Cite: A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ICJ	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis Biochemistry, 35, 1996
9FZK	SARS CoV-2 nsp10 in complex with theExoN domain from nsp14 Descriptor: Guanine-N7 methyltransferase nsp14, Non-structural protein 11, ZINC ION Authors: Fisher, S.Z. Deposit date: 2024-07-05 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (1.3 Å) Cite: SARS CoV-2 nsp10 in complex with theExoN domain from nsp14 To Be Published
8ZND	Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH and a substrate in the steady stage of reaction Descriptor: Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Wakabayashi, T, Nakasako, M. Deposit date: 2024-05-26 Release date: 2024-06-12 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action To Be Published
8Y7X	Structure of HCoV-HKU1A spike in the functionally anchored-3up conformation with 3TMPRSS2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. Deposit date: 2024-02-05 Release date: 2024-07-17 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024
8Y16	Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... Authors: Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. Deposit date: 2024-01-23 Release date: 2024-07-03 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants. Structure, 2024

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