5TYX
 
 | | DNA Polymerase Mu Product Complex, Mn2+ (15 min) | | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... | | Authors: | Jamsen, J.A, Wilson, S.H. | | Deposit date: | 2016-11-21 | | Release date: | 2017-08-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.948 Å) | | Cite: | Time-lapse crystallography snapshots of a double-strand break repair polymerase in action.
Nat Commun, 8, 2017
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5TYE
 | | DNA Polymerase Mu Product Complex, 10 mM Mg2+ (60 min) | | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Jamsen, J.A, Wilson, S.H. | | Deposit date: | 2016-11-19 | | Release date: | 2017-08-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.047 Å) | | Cite: | Time-lapse crystallography snapshots of a double-strand break repair polymerase in action.
Nat Commun, 8, 2017
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2QJ1
 | | Crystal structure of infectious bursal disease virus VP1 polymerase incubated with an oligopeptide mimicking the VP3 C-terminus | | Descriptor: | Infectious bursal disease virus VP1 polymerase | | Authors: | Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N. | | Deposit date: | 2007-07-06 | | Release date: | 2007-11-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.48 Å) | | Cite: | Unprecedented activation mechanism of a non-canonical RNA-dependent RNA polymerase
To be Published
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4M3O
 | | Crystal structure of K.lactis Rtr1 NTD | | Descriptor: | KLLA0F12672p, ZINC ION | | Authors: | Hsu, P.L, Yang, W, Zheng, N, Varani, G. | | Deposit date: | 2013-08-06 | | Release date: | 2014-07-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD.
J.Mol.Biol., 426, 2014
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8F72
 | | Phage P32 gp64- RNA polymerase | | Descriptor: | MAGNESIUM ION, TPR_REGION domain-containing protein | | Authors: | Bae, B, Nair, S.K. | | Deposit date: | 2022-11-17 | | Release date: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Thermophage RNA polymerase
To Be Published
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2MOW
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2WNM
 | | Solution structure of Gp2 | | Descriptor: | GENE 2 | | Authors: | Camara, B, Liu, M, Shadrinc, A, Liu, B, Simpson, P, Weinzierl, R, Severinovc, K, Cota, E, Matthews, S, Wigneshweraraj, S.R. | | Deposit date: | 2009-07-13 | | Release date: | 2010-02-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | T7 Phage Protein Gp2 Inhibits the Escherichia Coli RNA Polymerase by Antagonizing Stable DNA Strand Separation Near the Transcription Start Site.
Proc.Natl.Acad.Sci.USA, 107, 2010
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5UI6
 | | Solution NMR Structure of Lasso Peptide Acinetodin | | Descriptor: | Acinetodin | | Authors: | Bushin, L.B, Metelev, M, Severinov, K, Seyedsayamdost, M.R. | | Deposit date: | 2017-01-12 | | Release date: | 2017-02-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.
ACS Chem. Biol., 12, 2017
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5UI7
 | | Solution NMR Structure of Lasso Peptide Klebsidin | | Descriptor: | Klebsidin | | Authors: | Bushin, L.B, Metelev, M, Severinov, K, Seyedsayamdost, M.R. | | Deposit date: | 2017-01-13 | | Release date: | 2017-02-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.
ACS Chem. Biol., 12, 2017
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3UB0
 | | Crystal structure of the nonstructural protein 7 and 8 complex of Feline Coronavirus | | Descriptor: | Non-structural protein 6, nsp6,, Non-structural protein 7, ... | | Authors: | Xiao, Y, Hilgenfeld, R, Ma, Q. | | Deposit date: | 2011-10-22 | | Release date: | 2012-02-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Nonstructural proteins 7 and 8 of feline coronavirus form a 2:1 heterotrimer that exhibits primer-independent RNA polymerase activity.
J.Virol., 86, 2012
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7Y9Y
 | | Structure of the Cas7-11-Csx29-guide RNA-target RNA (no PFS) complex | | Descriptor: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (27-MER), ... | | Authors: | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | | Deposit date: | 2022-06-26 | | Release date: | 2022-11-09 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease.
Science, 378, 2022
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7Y9X
 | | Structure of the Cas7-11-Csx29-guide RNA complex | | Descriptor: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ... | | Authors: | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | | Deposit date: | 2022-06-26 | | Release date: | 2022-11-09 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.49 Å) | | Cite: | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease.
Science, 378, 2022
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2ZNI
 | | Crystal structure of Pyrrolysyl-tRNA synthetase-tRNA(Pyl) complex from Desulfitobacterium hafniense | | Descriptor: | CALCIUM ION, Pyrrolysyl-tRNA synthetase, bacterial tRNA | | Authors: | Nozawa, K, Araiso, Y, Soll, D, Ishitani, R, Nureki, O. | | Deposit date: | 2008-04-25 | | Release date: | 2008-12-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality
Nature, 457, 2009
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2O8K
 | | NMR Structure of the Sigma-54 RpoN Domain Bound to the-24 Promoter Element | | Descriptor: | 5'-D(*GP*AP*AP*AP*CP*GP*TP*GP*CP*CP*AP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*GP*CP*AP*CP*GP*TP*TP*TP*C)-3', RNA polymerase sigma factor RpoN | | Authors: | Doucleff, M, Pelton, J.G, Lee, P.S, Wemmer, D.E. | | Deposit date: | 2006-12-12 | | Release date: | 2007-07-17 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structural basis of DNA recognition by the alternative sigma-factor, sigma54.
J.Mol.Biol., 369, 2007
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4FQG
 | | Crystal structure of the TCERG1 FF4-6 tandem repeat domain | | Descriptor: | CHLORIDE ION, NICKEL (II) ION, Transcription elongation regulator 1 | | Authors: | Liu, J, Fan, S, Lee, C.J, Greenleaf, A.L, Zhou, P. | | Deposit date: | 2012-06-25 | | Release date: | 2013-02-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat.
J.Biol.Chem., 288, 2013
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5HCI
 | | GPN-loop GTPase Npa3 in complex with GDP | | Descriptor: | GLYCEROL, GPN-loop GTPase 1, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | | Deposit date: | 2016-01-04 | | Release date: | 2016-01-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly.
Mol.Cell.Biol., 36, 2015
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5HCN
 | | GPN-loop GTPase Npa3 in complex with GMPPCP | | Descriptor: | GLYCEROL, GPN-loop GTPase 1, LAURIC ACID, ... | | Authors: | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | | Deposit date: | 2016-01-04 | | Release date: | 2016-01-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly.
Mol.Cell.Biol., 36, 2015
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2P4V
 | | Crystal structure of the transcript cleavage factor, GreB at 2.6A resolution | | Descriptor: | Transcription elongation factor greB | | Authors: | Vassylyeva, M.N, Svetlov, V, Dearborn, A.D, Klyuyev, S, Artsimovitch, I, Vassylyev, D.G. | | Deposit date: | 2007-03-13 | | Release date: | 2008-01-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The carboxy-terminal coiled-coil of the RNA polymerase beta'-subunit is the main binding site for Gre factors.
Embo Rep., 8, 2007
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1DDE
 | | STRUCTURE OF THE DNAG CATALYTIC CORE | | Descriptor: | DNA PRIMASE, YTTRIUM ION | | Authors: | Keck, J.L, Roche, D.D, Lynch, A.S, Berger, J.M. | | Deposit date: | 1999-11-09 | | Release date: | 2000-04-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of the RNA polymerase domain of E. coli primase.
Science, 287, 2000
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1DD9
 | | STRUCTURE OF THE DNAG CATALYTIC CORE | | Descriptor: | DNA PRIMASE, STRONTIUM ION | | Authors: | Keck, J.L, Roche, D.D, Lynch, A.S, Berger, J.M. | | Deposit date: | 1999-11-09 | | Release date: | 2000-04-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of the RNA polymerase domain of E. coli primase.
Science, 287, 2000
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8B8B
 | | Multimerization domain of Munia virus 1 phosphoprotein | | Descriptor: | Munia Bornavirus 1 phosphoprotein, NITRATE ION | | Authors: | Chenavier, F, Tarbouriech, N, Bourhis, J.M, Tomonaga, K, Horie, M, Crepin, T. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-23 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing.
Viruses, 14, 2022
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2KM4
 | | Solution structure of Rtt103 CTD interacting domain | | Descriptor: | Regulator of Ty1 transposition protein 103 | | Authors: | Lunde, B.M, Reichow, S, Kim, M, Leeper, T.C, Becker, R, Buratowski, S, Meinhart, A, Varani, G. | | Deposit date: | 2009-07-20 | | Release date: | 2010-09-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
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1XJR
 | | The Structure of a Rigorously Conserved RNA Element Within the SARS Virus Genome | | Descriptor: | MAGNESIUM ION, s2m RNA | | Authors: | Robertson, M.P, Igel, H, Baertsch, R, Haussler, D, Ares Jr, M, Scott, W.G. | | Deposit date: | 2004-09-24 | | Release date: | 2005-02-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The structure of a rigorously conserved RNA element within the SARS virus genome
Plos Biol., 3, 2005
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1YMO
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3K8D
 | | Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase in complex with CTP and 2-deoxy-Kdo | | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, 3-deoxy-manno-octulosonate cytidylyltransferase, CYTIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Heyes, D.J, Levy, C.W, Lafite, P, Scrutton, N.S, Leys, D. | | Deposit date: | 2009-10-14 | | Release date: | 2009-11-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases
J.Biol.Chem., 284, 2009
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