7MWS
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![BU of 7mws by Molmil](/molmil-images/mine/7mws) | Crystal structure of tamarin CD81 large extracellular loop | Descriptor: | CD81 protein, GLYCEROL, TETRAETHYLENE GLYCOL | Authors: | Kumar, A, Hossain, R.A, Yost, S.A, Bu, W, Wang, Y, Dearborn, A.D, Grakoui, A, Cohen, J.I, Marcotrigiano, J. | Deposit date: | 2021-05-17 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into hepatitis C virus receptor binding and entry. Nature, 598, 2021
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6HVV
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![BU of 6hvv by Molmil](/molmil-images/mine/6hvv) | Yeast 20S proteasome with human beta2i (1-53) in complex with 39 | Descriptor: | (2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Huber, E.M, Groll, M. | Deposit date: | 2018-10-11 | Release date: | 2019-01-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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6HWD
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![BU of 6hwd by Molmil](/molmil-images/mine/6hwd) | Yeast 20S proteasome beta2-G45A mutant in complex with bortezomib | Descriptor: | CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... | Authors: | Huber, E.M, Groll, M. | Deposit date: | 2018-10-11 | Release date: | 2019-01-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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6KDF
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![BU of 6kdf by Molmil](/molmil-images/mine/6kdf) | Crystal structure of the alpha beta heterodimer of human IDH3 in APO form. | Descriptor: | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta | Authors: | Sun, P, Ding, J. | Deposit date: | 2019-07-02 | Release date: | 2019-09-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase. J.Biol.Chem., 294, 2019
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6HVA
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![BU of 6hva by Molmil](/molmil-images/mine/6hva) | Yeast 20S proteasome with human beta2i (1-53) in complex with 13 | Descriptor: | (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Huber, E.M, Groll, M. | Deposit date: | 2018-10-10 | Release date: | 2019-01-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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7MPU
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![BU of 7mpu by Molmil](/molmil-images/mine/7mpu) | Brucella melitensis NrnC bound to pGG | Descriptor: | 5'-phosphorylated GG, NanoRNase C, SULFATE ION | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2021-05-04 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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6HW9
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![BU of 6hw9 by Molmil](/molmil-images/mine/6hw9) | Yeast 20S proteasome in complex with 41b | Descriptor: | (2~{S})-3-(4-methoxyphenyl)-~{N}-[(2~{S},3~{R})-4-methyl-1-(4-methylcyclohexyl)-3,4-bis(oxidanyl)pentan-2-yl]-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Huber, E.M, Groll, M. | Deposit date: | 2018-10-11 | Release date: | 2019-01-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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6KH3
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![BU of 6kh3 by Molmil](/molmil-images/mine/6kh3) | Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes | Descriptor: | FE (III) ION, Ferritin, NICKEL (II) ION | Authors: | Gu, C, Chen, H, Wang, Y, Zhang, T, Wang, H, Zhao, G. | Deposit date: | 2019-07-12 | Release date: | 2020-01-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes. Chemistry, 26, 2020
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7MQJ
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![BU of 7mqj by Molmil](/molmil-images/mine/7mqj) | Dhr1 Helicase Core | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable ATP-dependent RNA helicase DHR1 | Authors: | Miller, L, Chaker-Margot, M, Klinge, S. | Deposit date: | 2021-05-05 | Release date: | 2021-09-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
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7MJ1
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![BU of 7mj1 by Molmil](/molmil-images/mine/7mj1) | LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with NAD | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P. | Deposit date: | 2021-04-19 | Release date: | 2021-09-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.402 Å) | Cite: | The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 118, 2021
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6KL2
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![BU of 6kl2 by Molmil](/molmil-images/mine/6kl2) | |
7MJ0
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![BU of 7mj0 by Molmil](/molmil-images/mine/7mj0) | LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with adenosine monophosphate AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase | Authors: | Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P. | Deposit date: | 2021-04-19 | Release date: | 2021-09-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MJ2
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![BU of 7mj2 by Molmil](/molmil-images/mine/7mj2) | LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with Zn | Descriptor: | MAGNESIUM ION, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase, ZINC ION | Authors: | Chatterjee, S, Rankin, J.A, Lagishetty, S, Hu, J, Hausinger, R.P. | Deposit date: | 2021-04-19 | Release date: | 2021-09-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MUQ
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![BU of 7muq by Molmil](/molmil-images/mine/7muq) | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 1 | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | Deposit date: | 2021-05-14 | Release date: | 2021-10-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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7MUY
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![BU of 7muy by Molmil](/molmil-images/mine/7muy) | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 5 | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | Deposit date: | 2021-05-14 | Release date: | 2021-10-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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7MUV
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![BU of 7muv by Molmil](/molmil-images/mine/7muv) | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 3 | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | Deposit date: | 2021-05-14 | Release date: | 2021-10-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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7MUW
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![BU of 7muw by Molmil](/molmil-images/mine/7muw) | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 4 | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | Deposit date: | 2021-05-14 | Release date: | 2021-10-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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7MUD
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![BU of 7mud by Molmil](/molmil-images/mine/7mud) | Legionella pneumophila Dot/Icm T4SS OMC | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | Deposit date: | 2021-05-14 | Release date: | 2021-10-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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7MUS
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![BU of 7mus by Molmil](/molmil-images/mine/7mus) | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 2 | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | Deposit date: | 2021-05-14 | Release date: | 2021-10-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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6HW3
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![BU of 6hw3 by Molmil](/molmil-images/mine/6hw3) | Yeast 20S proteasome in complex with 13 | Descriptor: | (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Huber, E.M, Groll, M. | Deposit date: | 2018-10-11 | Release date: | 2019-01-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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7MUC
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![BU of 7muc by Molmil](/molmil-images/mine/7muc) | Legionella pneumophila Dot/Icm T4SS C1 Reconstruction | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | Deposit date: | 2021-05-14 | Release date: | 2021-10-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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6KDK
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![BU of 6kdk by Molmil](/molmil-images/mine/6kdk) | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dCTP ternary complex | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2019-07-02 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
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7MUE
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![BU of 7mue by Molmil](/molmil-images/mine/7mue) | Legionella pneumophila Dot/Icm T4SS PR | Descriptor: | DotF, IcmE protein, Type IV secretion protein IcmK, ... | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | Deposit date: | 2021-05-14 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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7MJP
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![BU of 7mjp by Molmil](/molmil-images/mine/7mjp) | Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Sung, M.W, Shyng, S.L. | Deposit date: | 2021-04-20 | Release date: | 2021-10-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proc.Natl.Acad.Sci.USA, 118, 2021
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6HTR
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![BU of 6htr by Molmil](/molmil-images/mine/6htr) | Yeast 20S proteasome with human beta2c (S171G) in complex with 13 | Descriptor: | (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, MAGNESIUM ION, PROTEASOME SUBUNIT ALPHA TYPE-1, ... | Authors: | Huber, E.M, Groll, M. | Deposit date: | 2018-10-04 | Release date: | 2019-01-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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