8SHF
 
 | | CCT-G beta 5 complex closed state 7 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | | Deposit date: | 2023-04-14 | | Release date: | 2023-11-01 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
|
|
8SHN
 | | CCT-G beta 5 complex closed state 6 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | | Deposit date: | 2023-04-14 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
|
|
8SUZ
 | | Open State of the SARS-CoV-2 Envelope Protein Transmembrane Domain, Determined by Solid-State NMR | | Descriptor: | Envelope small membrane protein | | Authors: | Medeiros-Silva, J, Dregni, A.J, Somberg, N.H, Hong, M. | | Deposit date: | 2023-05-14 | | Release date: | 2023-10-25 | | Last modified: | 2024-05-15 | | Method: | SOLID-STATE NMR | | Cite: | Atomic structure of the open SARS-CoV-2 E viroporin.
Sci Adv, 9, 2023
|
|
7REB
 | | E. coli dihydrofolate reductase complexed with 5-(3-(7-(4-(aminomethyl)phenyl)benzo[d][1,3]dioxol-5-yl)but-1-yn-1-yl)-6-ethylpyrimidine-2,4-diamine (UCP1223) | | Descriptor: | 5-[(3R)-3-{7-[4-(aminomethyl)phenyl]-2H-1,3-benzodioxol-5-yl}but-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine, Dihydrofolate reductase, SULFATE ION | | Authors: | Lombardo, M.N, Wright, D.L. | | Deposit date: | 2021-07-12 | | Release date: | 2022-07-27 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
Commun Biol, 5, 2022
|
|
8SHG
 | | CCT G beta 5 complex closed state 9 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | | Deposit date: | 2023-04-14 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
|
|
8SHQ
 | | CCT G beta 5 complex closed state 12 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | | Deposit date: | 2023-04-14 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
|
|
8S9E
 | | Solution structure of jarastatin (rJast), a disintegrin from Bothrops jararaca | | Descriptor: | Disintegrin jarastatin | | Authors: | Vasconcelos, A.A, Estrada, J.E.C, Zingali, R.B, Almeida, F.C.L. | | Deposit date: | 2023-03-28 | | Release date: | 2023-11-29 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Toward the mechanism of jarastatin (rJast) inhibition of the integrin alpha V beta 3.
Int.J.Biol.Macromol., 255, 2024
|
|
8GXX
 | | 3 nucleotide-bound V1EG of V/A-ATPase from Thermus thermophilus. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2022-09-21 | | Release date: | 2023-01-25 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding.
J.Biol.Chem., 299, 2023
|
|
8GXY
 | | 2 sulfate-bound V1EG of V/A-ATPase from Thermus thermophilus. | | Descriptor: | SULFATE ION, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2022-09-21 | | Release date: | 2023-01-25 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding.
J.Biol.Chem., 299, 2023
|
|
8GXZ
 | | 1 sulfate and 1 ATP bound V1EG of V/A-ATPase from Thermus thermophilus. | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2022-09-21 | | Release date: | 2023-01-25 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding.
J.Biol.Chem., 299, 2023
|
|
8GXW
 | | 2 ATP-bound V1EG of V/A-ATPase from Thermus thermophilus | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2022-09-21 | | Release date: | 2023-01-25 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding.
J.Biol.Chem., 299, 2023
|
|
8SH2
 | | KLHDC2 in complex with EloB and EloC | | Descriptor: | Elongin-B, Elongin-C, Kelch domain-containing protein 2 | | Authors: | Digianantonio, K.M, Bekes, M. | | Deposit date: | 2023-04-13 | | Release date: | 2024-01-03 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat.Struct.Mol.Biol., 31, 2024
|
|
1A11
 | | NMR STRUCTURE OF MEMBRANE SPANNING SEGMENT 2 OF THE ACETYLCHOLINE RECEPTOR IN DPC MICELLES, 10 STRUCTURES | | Descriptor: | ACETYLCHOLINE RECEPTOR M2 | | Authors: | Gesell, J.J, Sun, W, Montal, M, Opella, S.J. | | Deposit date: | 1997-12-19 | | Release date: | 1998-04-08 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy.
Nat.Struct.Biol., 6, 1999
|
|
8HS3
 | | Gi bound orphan GPR20 in ligand-free state | | Descriptor: | Ggama, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Lin, X, Jiang, S, Xu, F. | | Deposit date: | 2022-12-16 | | Release date: | 2023-03-08 | | Last modified: | 2023-03-15 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | The activation mechanism and antibody binding mode for orphan GPR20.
Cell Discov, 9, 2023
|
|
8HSC
 | | Gi bound Orphan GPR20 complex with Fab046 in ligand-free state | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Lin, X, Jiang, S, Xu, F. | | Deposit date: | 2022-12-19 | | Release date: | 2023-03-08 | | Last modified: | 2023-03-15 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | The activation mechanism and antibody binding mode for orphan GPR20.
Cell Discov, 9, 2023
|
|
8S32
 | | GroEL with bound GroTAC peptide | | Descriptor: | Chaperonin GroEL, GroTAC | | Authors: | Wroblewski, K, Izert-Nowakowska, M.A, Goral, T.K, Klimecka, M.M, Kmiecik, S, Gorna, M.W. | | Deposit date: | 2024-02-19 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.45 Å) | | Cite: | Depletion of essential GroEL protein in Escherichia coli using Clp-Interacting Peptidic Protein Erasers (CLIPPERs)
To Be Published
|
|
6MG9
 | |
7RTT
 | | Cryo-EM structure of a TTYH2 cis-dimer | | Descriptor: | CALCIUM ION, Protein tweety homolog 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Li, B, Brohawn, S.G, Hoel, C.M. | | Deposit date: | 2021-08-15 | | Release date: | 2021-08-25 | | Last modified: | 2022-03-09 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca 2+ -dependent switch from intra- to intermembrane dimerization.
Nat Commun, 12, 2021
|
|
7RTU
 | | Cryo-EM structure of a TTYH2 trans-dimer | | Descriptor: | Protein tweety homolog 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Li, B, Brohawn, S.G, Hoel, C.M. | | Deposit date: | 2021-08-15 | | Release date: | 2021-08-25 | | Last modified: | 2022-03-09 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca 2+ -dependent switch from intra- to intermembrane dimerization.
Nat Commun, 12, 2021
|
|
7RTW
 | | Cryo-EM structure of a TTYH3 cis-dimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Li, B, Brohawn, S.G, Hoel, C.M. | | Deposit date: | 2021-08-15 | | Release date: | 2021-08-25 | | Last modified: | 2022-03-09 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca 2+ -dependent switch from intra- to intermembrane dimerization.
Nat Commun, 12, 2021
|
|
8SL4
 | | Dimeric form of human adenylyl cyclase 5 | | Descriptor: | Adenylate cyclase type 5 | | Authors: | Yen, Y.C, Tesmer, J.J.G. | | Deposit date: | 2023-04-20 | | Release date: | 2024-04-03 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Structure of adenylyl cyclase 5 in complex with G beta gamma offers insights into ADCY5-related dyskinesia.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8S03
 | | NMR solution structure of the CysD2 domain of MUC2 | | Descriptor: | CALCIUM ION, Mucin-2 | | Authors: | Recktenwald, C, Karlsson, B.G, Garcia-Bonnete, M.-J, Katona, G, Jensen, M, Lymer, R, Baeckstroem, M, Johansson, M.E.V, Hansson, G.C, Trillo-Muyo, S. | | Deposit date: | 2024-02-13 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking.
Cell Rep, 43, 2024
|
|
7S67
 | | Extended conformation of daytime state KaiC | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, ... | | Authors: | Sandate, C.R, Swan, J.A, Partch, C.L, Lander, G.C. | | Deposit date: | 2021-09-13 | | Release date: | 2021-09-22 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Coupling of distant ATPase domains in the circadian clock protein KaiC.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7RTV
 | | Cryo-EM structure of monomeric TTYH2 | | Descriptor: | Protein tweety homolog 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Li, B, Brohawn, S.G, Hoel, C.M. | | Deposit date: | 2021-08-15 | | Release date: | 2021-09-22 | | Last modified: | 2022-04-06 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca 2+ -dependent switch from intra- to intermembrane dimerization.
Nat Commun, 12, 2021
|
|
7RTM
 | | Cryo-EM Structure of the Sodium-driven Chloride/Bicarbonate Exchanger NDCBE (SLC4A8) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... | | Authors: | Wang, W.G, Tsirulnikov, K, Zhekova, H, Kayik, G, Muhammad-Khan, H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Zhou, Z.H, Pushkin, A, Kurtz, I. | | Deposit date: | 2021-08-13 | | Release date: | 2021-09-29 | | Last modified: | 2021-10-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE.
Nat Commun, 12, 2021
|
|
