7RTW

Cryo-EM structure of a TTYH3 cis-dimer

Summary for 7RTW

Entry DOI	10.2210/pdb7rtw/pdb
EMDB information	24691
Descriptor	Protein tweety homolog 3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	ttyh2, momomer, membrane protein
Biological source	Mus musculus (Mouse)
Total number of polymer chains	2
Total formula weight	119227.66
Authors	Li, B.,Brohawn, S.G.,Hoel, C.M. (deposition date: 2021-08-15, release date: 2021-08-25, Last modification date: 2022-03-09)
Primary citation	Li, B.,Hoel, C.M.,Brohawn, S.G. Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca 2+ -dependent switch from intra- to intermembrane dimerization. Nat Commun, 12:6913-6913, 2021 Cited by PubMed: 34824283 DOI: 10.1038/s41467-021-27283-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.23 Å)

Structure validation