8HSC

Gi bound Orphan GPR20 complex with Fab046 in ligand-free state

Summary for 8HSC

• Entry DOI: 10.2210/pdb8hsc/pdb
• EMDB information: 34993
• Descriptor: light chain of Fab046, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
• Functional Keywords: orphan receptor, gpcr, gpr20, gi-coupled, gpr20-gi-fab046, membrane protein
• Biological source: Rattus; More
• Total number of polymer chains: 7
• Total formula weight: 224707.03

Authors

Lin, X.,Jiang, S.,Xu, F. (deposition date: 2022-12-19, release date: 2023-03-08, Last modification date: 2023-03-15)

• Primary citation: Lin, X.,Jiang, S.,Wu, Y.,Wei, X.,Han, G.W.,Wu, L.,Liu, J.,Chen, B.,Zhang, Z.,Zhao, S.,Cherezov, V.,Xu, F.; The activation mechanism and antibody binding mode for orphan GPR20.; Cell Discov, 9:23-23, 2023; PubMed: 36849514; DOI: 10.1038/s41421-023-00520-8

Experimental method

ELECTRON MICROSCOPY (3.22 Å)