3UKI
| Crystal structure of reduced OxyR from Porphyromonas gingivalis | Descriptor: | OxyR | Authors: | Svintradze, D.V, Wright, H.T, Collazo-Santiago, E.A, Lewis, J.P. | Deposit date: | 2011-11-09 | Release date: | 2013-07-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Structures of the Porphyromonas gingivalis OxyR regulatory domain explain differences in expression of the OxyR regulon in Escherichia coli and P. gingivalis. Acta Crystallogr.,Sect.D, 69, 2013
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8JML
| Structure of Helicobacter pylori Soj protein mutant, D41A | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SpoOJ regulator (Soj) | Authors: | Wu, C.T, Chu, C.H, Sun, Y.J. | Deposit date: | 2023-06-05 | Release date: | 2024-05-29 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into the molecular mechanism of ParABS system in chromosome partition by HpParA and HpParB. Nucleic Acids Res., 52, 2024
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4AC6
| Corynebacterium glutamicum AcnR AU derivative structure | Descriptor: | GOLD ION, HTH-TYPE TRANSCRIPTIONAL REPRESSOR ACNR | Authors: | Garcia-Nafria, J, Baumgart, M, Turkenburg, J.P, Wilkinson, A.J, Bott, M, Wilson, K.S. | Deposit date: | 2011-12-14 | Release date: | 2012-12-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Crystal and Solution Studies Reveal that the Transcriptional Regulator Acnr of Corynebacterium Glutamicum is Regulated by Citrate:Mg2+ Binding to a Non-Canonical Pocket. J.Biol.Chem., 288, 2013
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1B4O
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6PV1
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6PV3
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7B5J
| Anti-CRISPR associated (Aca) protein, Aca2 | Descriptor: | Anti-CRISPR associated (Aca) protein, Aca2, GLYCEROL | Authors: | Usher, B, Birkholz, N, Fineran, P.C, Blower, T.R. | Deposit date: | 2020-12-03 | Release date: | 2021-06-23 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Crystal structure of the anti-CRISPR repressor Aca2. J.Struct.Biol., 213, 2021
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4P96
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5V7M
| PCNA mutant L126A/I128A Protein Defective in Gene Silencing | Descriptor: | MAGNESIUM ION, Proliferating cell nuclear antigen | Authors: | Kondratick, C.M, Litman, J.M, Washington, M.T, Dieckman, L.M. | Deposit date: | 2017-03-20 | Release date: | 2018-03-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structures of PCNA mutant proteins defective in gene silencing suggest a novel interaction site on the front face of the PCNA ring. PLoS ONE, 13, 2018
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3M66
| Crystal structure of human Mitochondrial Transcription Termination Factor 3 | Descriptor: | mTERF domain-containing protein 1, mitochondrial | Authors: | Spahr, H, Samuelsson, T, Hallberg, B.M, Gustafsson, C.M. | Deposit date: | 2010-03-15 | Release date: | 2010-05-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain. Biochem.Biophys.Res.Commun., 397, 2010
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6W4R
| Structure of Tdp1 catalytic domain in complex with inhibitor XZ633p | Descriptor: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-{[2-(2-hydroxyphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}benzene-1,2-dicarboxylic acid, ... | Authors: | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R, Waugh, D.S. | Deposit date: | 2020-03-11 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.819 Å) | Cite: | Tdp1 catalytic domain To Be Published
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5V3O
| Cereblon in complex with DDB1 and CC-220 | Descriptor: | (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... | Authors: | Matyskiela, M, Pagarigan, B, Chamberlain, P. | Deposit date: | 2017-03-07 | Release date: | 2017-05-03 | Last modified: | 2018-02-07 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos. J. Med. Chem., 61, 2018
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5V7K
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8RGH
| Structure of dynein-2 intermediate chain DYNC2I1 (WDR60) in complex with the dynein-2 heavy chain DYNC2H1. | Descriptor: | Cytoplasmic dynein 2 intermediate chain 1, Cytoplasmic dynein 2 intermediate chain 2, Cytoplasmic dynein 2 light intermediate chain 1, ... | Authors: | Mukhopadhyay, A.G, Toropova, K, Daly, L, Wells, J, Vuolo, L, Seda, M, Jenkins, D, Stephens, D.J, Roberts, A.J. | Deposit date: | 2023-12-13 | Release date: | 2024-03-20 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure and tethering mechanism of dynein-2 intermediate chains in intraflagellar transport. Embo J., 43, 2024
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6NFX
| MBTD1 MBT repeats | Descriptor: | GLYCEROL, MBT domain-containing protein 1,Enhancer of polycomb homolog 1, SODIUM ION, ... | Authors: | Zhang, H, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2018-12-21 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex. Cell Rep, 30, 2020
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6WX7
| SOX2 bound to Importin-alpha 2 | Descriptor: | Importin subunit alpha-1, Transcription factor SOX-2 | Authors: | Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N. | Deposit date: | 2020-05-09 | Release date: | 2020-10-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for nuclear import selectivity of pioneer transcription factor SOX2. Nat Commun, 12, 2021
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6WX8
| SOX2 bound to Importin-alpha 3 | Descriptor: | Importin subunit alpha-3, SULFATE ION, Transcription factor SOX-2 | Authors: | Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N. | Deposit date: | 2020-05-10 | Release date: | 2020-10-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for nuclear import selectivity of pioneer transcription factor SOX2. Nat Commun, 12, 2021
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6PV2
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6PV0
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7RMW
| Crystal structure of B. subtilis PurR bound to ppGpp | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, Pur operon repressor | Authors: | Schumacher, M.A. | Deposit date: | 2021-07-28 | Release date: | 2021-12-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus. Nucleic Acids Res., 50, 2022
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6WX9
| SOX2 bound to Importin-alpha 5 | Descriptor: | Importin subunit alpha-5, Transcription factor SOX-2 | Authors: | Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N. | Deposit date: | 2020-05-10 | Release date: | 2020-10-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for nuclear import selectivity of pioneer transcription factor SOX2. Nat Commun, 12, 2021
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7KQ1
| PCNA bound to truncated peptide mimetic | Descriptor: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | Authors: | Vandborg, B.A, Bruning, J.B. | Deposit date: | 2020-11-13 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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7KQ0
| PCNA bound to peptide mimetic | Descriptor: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-TYR-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | Authors: | Vandborg, B.A, Bruning, J.B. | Deposit date: | 2020-11-13 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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6G16
| Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange | Descriptor: | Histone-binding protein RBBP4, Metastasis-associated protein MTA1 | Authors: | Millard, C.J, Varma, N, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2018-03-20 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structure of the core NuRD repression complex provides insights into its interaction with chromatin. Elife, 5, 2016
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5XJP
| Crystal structure of response regulator AdeR receiver domain with Mg | Descriptor: | AdeR, MAGNESIUM ION | Authors: | Wen, Y. | Deposit date: | 2017-05-03 | Release date: | 2017-08-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.597 Å) | Cite: | Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region. Nucleic Acids Res., 45, 2017
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