2PEE
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![BU of 2pee by Molmil](/molmil-images/mine/2pee) | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State | Descriptor: | GLYCEROL, SULFATE ION, Serine protease inhibitor | Authors: | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | Deposit date: | 2007-04-02 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The N terminus of the serpin, tengpin, functions to trap the metastable native state. Embo Rep., 8, 2007
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4AJU
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![BU of 4aju by Molmil](/molmil-images/mine/4aju) | Crystal structure of the reactive loop cleaved ZPI in P41 space group | Descriptor: | 1,2-ETHANEDIOL, PROTEIN Z-DEPENDENT PROTEASE INHIBITOR, SULFATE ION | Authors: | Zhou, A, Yan, Y, Wei, Z. | Deposit date: | 2012-02-19 | Release date: | 2013-01-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
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4AJT
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![BU of 4ajt by Molmil](/molmil-images/mine/4ajt) | |
4AU4
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![BU of 4au4 by Molmil](/molmil-images/mine/4au4) | Crystal Structure of Hsp47 | Descriptor: | SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), MEMBER 1, ... | Authors: | Widmer, C, Gebauer, J.M, Brunstein, E, Rodenbaum, S, Zaucke, F, Drogemuller, C, Leeb, T, Baumann, U. | Deposit date: | 2012-05-14 | Release date: | 2012-08-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
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2RIW
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![BU of 2riw by Molmil](/molmil-images/mine/2riw) | The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin | Authors: | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | Deposit date: | 2007-10-12 | Release date: | 2008-10-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins J.Biol.Chem., 286, 2011
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3ZHA
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![BU of 3zha by Molmil](/molmil-images/mine/3zha) | |
4AQH
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![BU of 4aqh by Molmil](/molmil-images/mine/4aqh) | Plasminogen activator inhibitor type-1 in complex with the inhibitor AZ3976 | Descriptor: | PLASMINOGEN ACTIVATOR INHIBITOR 1, TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE | Authors: | Fjellstrom, O, Deinum, J, Sjogren, T, Johansson, C, Geschwindner, S, Nerme, V, Legnehed, A, McPheat, J, Olsson, K, Bodin, C, Gustafsson, D. | Deposit date: | 2012-04-17 | Release date: | 2012-11-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 that Accelerates the Transition Into the Latent Conformation J.Biol.Chem., 288, 2013
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4AFX
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![BU of 4afx by Molmil](/molmil-images/mine/4afx) | Crystal structure of the reactive loop cleaved ZPI in I2 space group | Descriptor: | CALCIUM ION, PHOSPHATE ION, PROTEIN Z DEPENDENT PROTEASE INHIBITOR, ... | Authors: | Zhou, A, Yan, Y, Wei, Z. | Deposit date: | 2012-01-23 | Release date: | 2013-01-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
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2QUG
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![BU of 2qug by Molmil](/molmil-images/mine/2qug) | Crystal structure of alpha-1-antitrypsin, crystal form A | Descriptor: | Alpha-1-antitrypsin | Authors: | Hansen, G, Morton, C.J, Pearce, M.C, Feil, S.C, Adams, J.J, Parker, M.W, Bottomley, S.P. | Deposit date: | 2007-08-05 | Release date: | 2008-08-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding. Protein Sci., 17, 2008
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4BB2
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![BU of 4bb2 by Molmil](/molmil-images/mine/4bb2) | Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone | Descriptor: | 1,2-ETHANEDIOL, CORTICOSTEROID-BINDING GLOBULIN, CYSTEINE, ... | Authors: | Gardill, B.R, Vogl, M.R, Lin, H, Hammond, G.L, Muller, Y.A. | Deposit date: | 2012-09-19 | Release date: | 2012-12-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences Plos One, 7, 2012
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4C49
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![BU of 4c49 by Molmil](/molmil-images/mine/4c49) | Reactive loop cleaved human CBG in complex with cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | Authors: | Chan, W.L, Zhou, A, Read, R.J. | Deposit date: | 2013-09-02 | Release date: | 2014-10-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Role of Sa-Hd Loop Movement in Cortisol Release Mechanism of Cbg To be Published
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2R9Y
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![BU of 2r9y by Molmil](/molmil-images/mine/2r9y) | Structure of antiplasmin | Descriptor: | Alpha-2-antiplasmin | Authors: | Law, R.H.P, Sofian, T, Kan, W.T, Horvath, A.J, Hitchen, C.R, Langendorf, C.G, Buckle, A.M, Whisstock, J.C, Coughlin, P.B. | Deposit date: | 2007-09-14 | Release date: | 2007-12-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | X-ray crystal structure of the fibrinolysis inhibitor {alpha}2-antiplasmin Blood, 111, 2008
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2RIV
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![BU of 2riv by Molmil](/molmil-images/mine/2riv) | Crystal structure of the reactive loop cleaved human Thyroxine Binding Globulin | Descriptor: | GLYCEROL, SULFATE ION, Thyroxine-binding globulin | Authors: | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | Deposit date: | 2007-10-12 | Release date: | 2008-10-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins J.Biol.Chem., 286, 2011
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4C41
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2VDX
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![BU of 2vdx by Molmil](/molmil-images/mine/2vdx) | |
2VDY
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![BU of 2vdy by Molmil](/molmil-images/mine/2vdy) | Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | Authors: | Zhou, A, Wei, Z, Read, R.J. | Deposit date: | 2007-10-13 | Release date: | 2008-05-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release. J.Mol.Biol., 380, 2008
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4CAA
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![BU of 4caa by Molmil](/molmil-images/mine/4caa) | CLEAVED ANTICHYMOTRYPSIN T345R | Descriptor: | ANTICHYMOTRYPSIN | Authors: | Lukacs, C.M, Christianson, D.W. | Deposit date: | 1997-08-14 | Release date: | 1998-02-25 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
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2V95
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![BU of 2v95 by Molmil](/molmil-images/mine/2v95) | Structure of Corticosteroid-Binding Globulin in complex with Cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | Authors: | Klieber, M.A, Muller, Y.A. | Deposit date: | 2007-08-21 | Release date: | 2007-09-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Corticosteroid-Binding Globulin: Structural Basis for Steroid Transport and Proteinase-Triggered Release J.Biol.Chem., 282, 2007
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2VH4
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![BU of 2vh4 by Molmil](/molmil-images/mine/2vh4) | Structure of a loop C-sheet serpin polymer | Descriptor: | TENGPIN | Authors: | Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M. | Deposit date: | 2007-11-19 | Release date: | 2008-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A Structural Basis for Loop C-Sheet Polymerization in Serpins. J.Mol.Biol., 376, 2008
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2WXX
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![BU of 2wxx by Molmil](/molmil-images/mine/2wxx) | |
2WY0
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![BU of 2wy0 by Molmil](/molmil-images/mine/2wy0) | Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122 | Descriptor: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | Authors: | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | Deposit date: | 2009-11-11 | Release date: | 2010-10-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
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2WXZ
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2XN6
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![BU of 2xn6 by Molmil](/molmil-images/mine/2xn6) | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein | Descriptor: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-6-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | Deposit date: | 2010-07-30 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins. J.Biol.Chem., 286, 2011
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2XN7
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![BU of 2xn7 by Molmil](/molmil-images/mine/2xn7) | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein (T405-CF) | Descriptor: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-5-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | Deposit date: | 2010-07-30 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins. J.Biol.Chem., 286, 2011
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2WY1
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