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5DEF
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BU of 5def by Molmil
Crystal structure of B*27:04 complex bound to the pVIPR peptide
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
Authors:Loll, B, Fabian, H, Huser, H, Hee, C.S, Uchanska-Ziegler, B, Ziegler, A.
Deposit date:2015-08-25
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis.
Arthritis Rheumatol, 68, 2016
5GRG
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BU of 5grg by Molmil
Crystal structure of dual peptide from EBV in complex with HLA-A*11:01
Descriptor: Beta-2-microglobulin, Epstein Barr Virus, Latent Membrane Protein 2 epitope, ...
Authors:Tadwal, V.S, Xiao, Z, Ren, E.C.
Deposit date:2016-08-11
Release date:2017-08-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens
Sci Rep, 7, 2017
5GSV
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BU of 5gsv by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 142-5
Descriptor: 10-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
Deposit date:2016-08-17
Release date:2017-04-26
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5D2L
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BU of 5d2l by Molmil
Crystal structure of TCR C7 in complex with HCMV NLV epitope presented by HLA-A2
Descriptor: ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C7 TCR alpha chain, ...
Authors:Gao, M, Mariuzza, R.A.
Deposit date:2015-08-05
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.511 Å)
Cite:Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015
5D7I
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BU of 5d7i by Molmil
Structure of human MR1-Ac-6-FP in complex with human MAIT M33.64 TCR
Descriptor: Beta-2-microglobulin, GLYCEROL, M33.64 TCR Alpha Chain, ...
Authors:Keller, A.N, Woolley, R.E, Rossjohn, J.
Deposit date:2015-08-14
Release date:2016-01-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44, 2016
1CE6
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BU of 1ce6 by Molmil
MHC CLASS I H-2DB COMPLEXED WITH A SENDAI VIRUS NUCLEOPROTEIN PEPTIDE
Descriptor: PROTEIN (HUMAN BETA-2 MICROGLOBULIN), PROTEIN (MHC CLASS I H-2DB HEAVY CHAIN), PROTEIN (SENDAI VIRUS NUCLEOPROTEIN), ...
Authors:Tormo, J, Jones, E.Y.
Deposit date:1999-03-17
Release date:1999-03-26
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity.
Immunity, 10, 1999
5ENW
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BU of 5enw by Molmil
Structure of HLA-A2:01 with peptide G9L
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Remesh, S.G, Zajonc, D.M.
Deposit date:2015-11-09
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
5EO0
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BU of 5eo0 by Molmil
Crystal Structure of HLA-B0702-RFL9
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
Authors:Josephs, T.M, Gras, S, Rossjohn, J.
Deposit date:2015-11-10
Release date:2016-02-24
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.
J Immunol., 196, 2016
5D5M
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BU of 5d5m by Molmil
Structure of human MR1-5-OP-RU in complex with human MAIT M33.64 TCR
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, ACETATE ION, Beta-2-microglobulin, ...
Authors:Keller, A.N, Birkinshaw, R.W, Rossjohn, J.
Deposit date:2015-08-11
Release date:2016-01-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44, 2016
5GR7
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BU of 5gr7 by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-1
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
Authors:Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
Deposit date:2016-08-08
Release date:2017-06-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
7JWI
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BU of 7jwi by Molmil
Crystal structure of B17.R2 TCR in complex with H2D-b-NP366
Descriptor: 1,2-ETHANEDIOL, B17.R2 TCR alpha chain, B17.R2 TCR beta chain, ...
Authors:Farenc, C, Rossjohn, J.
Deposit date:2020-08-25
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.
Science, 372, 2021
5GSB
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BU of 5gsb by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-3
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
Authors:Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
Deposit date:2016-08-15
Release date:2017-07-12
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5BJT
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BU of 5bjt by Molmil
Crystal structure of human FcRn with a peptide inhibitor at multiple sites
Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, peptide inhibitor
Authors:Nienaber, V, Badger, J.
Deposit date:2016-10-23
Release date:2017-03-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5EOT
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BU of 5eot by Molmil
Structure of HLA-A2:01 with peptide G13E
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Zajonc, D.M, Remesh, S.G.
Deposit date:2015-11-10
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
1OF2
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BU of 1of2 by Molmil
Crystal structure of HLA-B*2709 complexed with the vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408)
Descriptor: BETA-2-MICROGLOBULIN, GLYCEROL, HUMAN LYMPHOCYTE ANTIGEN HLA-B27, ...
Authors:Hulsmeyer, M, Fiorillo, M.T, Bettosini, F, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
Deposit date:2003-04-04
Release date:2004-01-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Dual, Hla-B27 Subtype-Dependent Conformation of a Self-Peptide
J.Exp.Med., 199, 2004
5D7L
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BU of 5d7l by Molmil
Structure of human MR1-5-OP-RU in complex with human MAV36 TCR
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, MAV36 TCR Alpha Chain, ...
Authors:Keller, A.N, Rossjohn, J.
Deposit date:2015-08-14
Release date:2016-01-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44, 2016
5CS7
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BU of 5cs7 by Molmil
The crystal structure of wt beta2-microglobulin at room temperature
Descriptor: Beta-2-microglobulin
Authors:de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
5DDH
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BU of 5ddh by Molmil
Structure of HLA-A2:01 with the 12-mer peptide F12K
Descriptor: 12-mer peptide F12K, Beta-2-microglobulin, GLYCEROL, ...
Authors:Remesh, S.G, Zajonc, D.
Deposit date:2015-08-24
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove.
Elife, 5, 2016
5DEG
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BU of 5deg by Molmil
Crystal structure of B*27:06 bound to the pVIPR peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
Authors:Loll, B, Fabian, H, Hee, C.S, Huser, H, Uchanska-Ziegler, B, Ziegler, A.
Deposit date:2015-08-25
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis.
Arthritis Rheumatol, 68, 2016
7LLI
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BU of 7lli by Molmil
Stimulatory immune receptor protein complex
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
Authors:Rice, M.T, Littler, D.R, Rossjohn, J, Gully, B.S.
Deposit date:2021-02-04
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Recognition of the antigen-presenting molecule MR1 by a V delta 3 + gamma delta T cell receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LLJ
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BU of 7llj by Molmil
Inhibitory immune receptor protein complex
Descriptor: Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide, ...
Authors:Rice, M.T, Littler, D.R, Rossjohn, J, Gully, B.S.
Deposit date:2021-02-04
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Recognition of the antigen-presenting molecule MR1 by a V delta 3 + gamma delta T cell receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
5BS0
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BU of 5bs0 by Molmil
MAGE-A3 Reactive TCR in complex with Titin Epitope in HLA-A1
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, Lomax, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K.
Deposit date:2015-06-01
Release date:2016-03-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep, 6, 2016
5GRD
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BU of 5grd by Molmil
Crystal structure of 10-mer peptide from EBV in complex with HLA-A1101.
Descriptor: Beta-2-microglobulin, Epstein Barr Virus, Latent membrane protein 2 epitope, ...
Authors:Tadwal, V.S, Xiao, Z, Ren, E.C.
Deposit date:2016-08-10
Release date:2017-08-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens
Sci Rep, 7, 2017
5HYJ
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BU of 5hyj by Molmil
1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA
Descriptor: ALA-GLN-TRP-GLY-PRO-ASP-PRO-ALA-ALA-ALA, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
Deposit date:2016-02-01
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:A "hotspot" for autoimmune T cells in type 1 diabetes.
J.Clin.Invest., 126, 2016
1A1N
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BU of 1a1n by Molmil
MHC CLASS I MOLECULE B*3501 COMPLEXED WITH PEPTIDE VPLRPMTY FROM THE NEF PROTEIN (75-82) OF HIV1
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, BW-53 B*5301 alpha chain, ...
Authors:Smith, K.J, Reid, S.W, Stuart, D.I, Mcmichael, A.J, Jones, E.Y, Bell, J.I.
Deposit date:1997-12-11
Release date:1998-04-08
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501.
Immunity, 4, 1996

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