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8IK5	Transcription factor LMX1a homeobox domain in complex with Wnt1 promoter Descriptor: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), GLYCEROL, ... Authors: Lv, M.Q, Lin, L.Q. Deposit date: 2023-02-28 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (1.989 Å) Cite: Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain Febs J., 2024
4BXZ	RNA Polymerase II-Bye1 complex Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. Deposit date: 2013-07-16 Release date: 2013-09-11 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (4.8 Å) Cite: Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
3HKZ	The X-ray crystal structure of RNA polymerase from Archaea Descriptor: DNA-directed RNA polymerase subunit 13, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... Authors: Murakami, K.S. Deposit date: 2009-05-26 Release date: 2009-06-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.4 Å) Cite: The X-ray crystal structure of RNA polymerase from Archaea. Nature, 451, 2008
6ZGL	Structure of DPS determined by movement-free cryoEM with zero dose extrapolation Descriptor: DNA protection during starvation protein Authors: Naydenova, K, Russo, C.J. Deposit date: 2020-06-19 Release date: 2020-10-21 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (1.9 Å) Cite: Cryo-EM with sub-1 angstrom specimen movement. Science, 370, 2020
7F4G	Structure of RPAP2-bound RNA polymerase II Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y. Deposit date: 2021-06-18 Release date: 2021-07-07 Last modified: 2022-07-20 Method: ELECTRON MICROSCOPY (2.78 Å) Cite: RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex. Cell Rep, 39, 2022
7MBM	Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode01 Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... Authors: Park, S.H, Ayoub, A, Lee, Y.T, Dou, Y, Cho, U. Deposit date: 2021-04-01 Release date: 2021-12-29 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY Cite: Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes. Biochemistry, 61, 2022
7MBN	Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode02 Descriptor: DNA (146-MER), Histone H2A, Histone H2B 1.1, ... Authors: Park, S.H, Ayoub, A, Lee, Y.T, Dou, Y, Cho, U. Deposit date: 2021-04-01 Release date: 2021-12-29 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY Cite: Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes. Biochemistry, 61, 2022
5ODP	Salinibacter ruber Single-Strand Binding protein D17K D71K mutant Descriptor: DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Single-stranded DNA-binding protein Authors: Pierechod, M, Rothweiler, U. Deposit date: 2017-07-06 Release date: 2018-08-01 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.535 Å) Cite: Salinibacter ruber Single-Strand Binding protein D17K D71K mutant To Be Published
2CKZ	X-ray structure of RNA polymerase III subcomplex C17-C25. Descriptor: DNA-DIRECTED RNA POLYMERASE III 18 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE III 25 KD POLYPEPTIDE Authors: Jasiak, A.J, Armache, K.-J, Martens, B, Jansen, R.-P, Cramer, P. Deposit date: 2006-04-24 Release date: 2006-07-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural Biology of RNA Polymerase III: Subcomplex C17/-C25 X-Ray Structure and 11-Subunit Enzyme Model Mol.Cell, 23, 2006
8PP6	human RYBP-PRC1 bound to H2AK118ub1 nucleosome Descriptor: DNA (215-MER), Histone H2A, Histone H2B, ... Authors: Ciapponi, M, Benda, C, Mueller, J. Deposit date: 2023-07-06 Release date: 2024-04-03 Last modified: 2024-07-31 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. Nat.Struct.Mol.Biol., 31, 2024
8ILW	Transcription factor LMX1a homeobox domain in complex with Pitx3 promoter Descriptor: DNA (5'-D(*CP*AP*AP*CP*AP*CP*TP*TP*AP*AP*TP*CP*CP*AP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*TP*GP*GP*AP*TP*TP*AP*AP*GP*TP*GP*TP*T)-3'), LMX1A factor Authors: Lv, M.Q, Lin, L.Q. Deposit date: 2023-03-04 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (2.712 Å) Cite: Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain Febs J., 2024
8IKE	Transcription factors LMX1a mutant-R199A homeobox domain complex with Wnt1 promoter Descriptor: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), LMX1A factor Authors: Lv, M.Q, Lin, L.Q. Deposit date: 2023-02-28 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain Febs J., 2024
8TKQ	Cryo-EM structure of human full-length RAD52 Descriptor: DNA repair protein RAD52 homolog Authors: Schnicker, N.J, Razzaghi, M, Spies, M. Deposit date: 2023-07-25 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: A double-ring of human RAD52 remodels replication forks restricting fork reversal To Be Published
3NHZ	Structure of N-terminal Domain of MtrA Descriptor: MAGNESIUM ION, Two component system transcriptional regulator mtrA Authors: Barbieri, C.M, Mack, T.R, Robinson, V.L, Miller, M.T, Stock, A.M. Deposit date: 2010-06-14 Release date: 2010-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Regulation of response regulator autophosphorylation through interdomain contacts. J.Biol.Chem., 285, 2010
3AYH	Crystal structure of the C17/25 subcomplex from S. pombe RNA Polymerase III Descriptor: DNA-directed RNA polymerase III subunit rpc8, DNA-directed RNA polymerase III subunit rpc9, SULFATE ION Authors: Ehara, H, Sekine, S, Yokoyama, S. Deposit date: 2011-05-06 Release date: 2011-07-13 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.193 Å) Cite: Crystal structure of the C17/25 subcomplex from Schizosaccharomyces pombe RNA polymerase III Protein Sci., 20, 2011
3GFK	Crystal structure of Bacillus subtilis Spx/RNA polymerase alpha subunit C-terminal domain complex Descriptor: DNA-directed RNA polymerase subunit alpha, Regulatory protein spx Authors: Lamour, V, Westblade, L.F, Campbell, E.A, Darst, S.A. Deposit date: 2009-02-27 Release date: 2009-03-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the in vivo-assembled Bacillus subtilis Spx/RNA polymerase alpha subunit C-terminal domain complex J.Struct.Biol., 168, 2009
6J4F	Crystal structure of the AtWRKY2 domain Descriptor: DNA (5'-D(*AP*GP*CP*CP*TP*TP*TP*GP*AP*CP*CP*AP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*TP*GP*GP*TP*CP*AP*AP*AP*GP*GP*C)-3'), Probable WRKY transcription factor 2, ... Authors: Xu, Y.P, Xu, H, Wang, B, Su, X.D. Deposit date: 2019-01-08 Release date: 2020-01-15 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of the AtWRKY2 domain To Be Published
2ISI	Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand Descriptor: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION, PHOSPHATE ION Authors: Agarwal, R, Naidu, M.D. Deposit date: 2006-10-17 Release date: 2006-10-31 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Crystal structure of hApe1 in a new crystal form with a bound ligand: implications on catalytic mechanism and its inhibition To be Published
7RSU	TNA polymerase, n+2 product Descriptor: DNA polymerase, Primer, Template Authors: Maola, V, Chaput, J, Chim, N. Deposit date: 2021-08-11 Release date: 2021-10-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities. J.Am.Chem.Soc., 143, 2021
6J4E	Crystal structure of the AtWRKY1 domain Descriptor: DNA (5'-D(*AP*GP*CP*CP*TP*TP*TP*GP*AP*CP*CP*AP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*TP*GP*GP*TP*CP*AP*AP*AP*GP*GP*C)-3'), WRKY transcription factor 1, ... Authors: Xu, Y.P, Xu, H, Wang, B, Su, X.D. Deposit date: 2019-01-08 Release date: 2020-01-15 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.126 Å) Cite: Crystal structure of the AtWRKY1 domain To Be Published
3QT1	RNA polymerase II variant containing A Chimeric RPB9-C11 subunit Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Ruan, W, Lehmann, E, Thomm, M, Kostrewa, D, Cramer, P. Deposit date: 2011-02-22 Release date: 2011-03-23 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (4.3 Å) Cite: Evolution of two modes of intrinsic RNA polymerase transcript cleavage. J.Biol.Chem., 286, 2011
1WCM	Complete 12-Subunit RNA Polymerase II at 3.8 Angstrom Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, ... Authors: Armache, K.-J, Mitterweger, S, Meinhart, A, Cramer, P. Deposit date: 2004-11-17 Release date: 2004-12-14 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structures of Complete RNA Polymerase II and its Subcomplex,Rpb4/7 J.Biol.Chem., 280, 2005
3QQC	Crystal structure of archaeal Spt4/5 bound to the RNAP clamp domain Descriptor: DNA-directed RNA polymerase subunit b, DNA-directed RNA polymerase subunit a', DNA-directed RNA polymerase subunit A'', ... Authors: Martinez-Rucobo, F.W. Deposit date: 2011-02-15 Release date: 2011-03-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity. Embo J., 30, 2011
7PNG	Solution structure of 1:1 complex of an indoloquinoline derivative SYUIQ-5 to parallel quadruplex-duplex (Q-D) hybrid Descriptor: DNA (37-MER), ~{N}-(5~{H}-indolo[3,2-b]quinolin-11-yl)-~{N}',~{N}'-dimethyl-propane-1,3-diamine Authors: Vianney, Y.M, Weisz, K. Deposit date: 2021-09-06 Release date: 2021-12-29 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces. Chemistry, 28, 2022
6W5N	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05) Descriptor: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. Deposit date: 2020-03-13 Release date: 2021-03-31 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (6 Å) Cite: Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021

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