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8GRF
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BU of 8grf by Molmil
Crystal structure of F-box protein in the ternary complex with adaptor protein Skp1(DL) and its substrate
Descriptor: 1,2-ETHANEDIOL, Citrate synthase, E3 ubiquitin ligase complex SCF subunit, ...
Authors:Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T.
Deposit date:2022-09-01
Release date:2023-04-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
8Y0W
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BU of 8y0w by Molmil
dormant ribosome with eIF5A, eEF2 and SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Du, M, Zeng, F.
Deposit date:2024-01-23
Release date:2024-02-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
7R0X
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BU of 7r0x by Molmil
Structure of the branching thioesterase from oocydin biosynthesis
Descriptor: Polyketide synthase
Authors:Fraley, A.E, Piel, J.
Deposit date:2022-02-02
Release date:2022-08-10
Last modified:2022-09-28
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structure of a Promiscuous Thioesterase Domain Responsible for Branching Acylation in Polyketide Biosynthesis.
Angew.Chem.Int.Ed.Engl., 61, 2022
7R72
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BU of 7r72 by Molmil
State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model
Descriptor: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-24
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
6BSW
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BU of 6bsw by Molmil
Crystal structure of Xyloglucan Xylosyltransferase 1 ternary form
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MANGANESE (II) ION, ...
Authors:Culbertson, A.T, Ehrlich, J.J, Choe, J, Honzatko, R.B, Zabotina, O.A.
Deposit date:2017-12-04
Release date:2018-05-23
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (2.156 Å)
Cite:Structure of xyloglucan xylosyltransferase 1 reveals simple steric rules that define biological patterns of xyloglucan polymers.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7R3F
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BU of 7r3f by Molmil
Monomeric PqsE mutant E187R
Descriptor: 2-aminobenzoylacetyl-CoA thioesterase, BENZOIC ACID, CACODYLATE ION, ...
Authors:Borgert, S.R, Schmelz, S, Blankenfeldt, W.
Deposit date:2022-02-07
Release date:2022-12-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.
Nat Commun, 13, 2022
8U06
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BU of 8u06 by Molmil
Imine reductase RedE bound with NADP+ and arcyriaflavin A (primary site)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Arcyriaflavin A, ...
Authors:Daniel-Ivad, P, Ryan, K.S.
Deposit date:2023-08-28
Release date:2024-09-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine
To be published
8U07
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BU of 8u07 by Molmil
Imine reductase RedE bound with NADP+ and arcyriaflavin A (secondary site)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Arcyriaflavin A, ...
Authors:Daniel-Ivad, P, Ryan, K.S.
Deposit date:2023-08-28
Release date:2024-09-04
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine
To be published
8U0H
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BU of 8u0h by Molmil
Crystal structure of PTPN2 with a PROTAC
Descriptor: (5P)-3-(carboxymethoxy)-4-chloro-5-(3-{[(4S)-1-({3-[2-(4-{3-[(3R)-2,6-dioxopiperidin-3-yl]-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl}piperidin-1-yl)acetamido]phenyl}methanesulfonyl)-2,2-dimethylpiperidin-4-yl]amino}phenyl)thiophene-2-carboxylic acid, ACETATE ION, PTPN2, ...
Authors:Jain, R, Longenecker, K, Qiu, W.
Deposit date:2023-08-29
Release date:2024-09-04
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Mechanistic insights into a heterobifunctional degrader-induced PTPN2/N1 complex.
Commun Chem, 7, 2024
8ULF
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BU of 8ulf by Molmil
Crystal structure of Plasmodium vivax CelTOS in complex with antibody 7g7
Descriptor: 7g7 heavy chain, 7g7 light chain, Pv cell-traversal protein, ...
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2023-10-16
Release date:2024-09-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria.
Nat Commun, 15, 2024
8UKH
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BU of 8ukh by Molmil
Crystal structure of Plasmodium falciparum CelTOS in complex with antibody 4h12
Descriptor: 4h12 heavy chain, 4h12 light chain, Cell traversal protein for ookinetes and sporozoites
Authors:Tang, W.K, Tolia, N.H, Urusova, D.
Deposit date:2023-10-13
Release date:2024-09-11
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria.
Nat Commun, 15, 2024
3UT9
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BU of 3ut9 by Molmil
Crystal Structure of Nucleosome Core Particle Assembled with a Palindromic Widom '601' Derivative (NCP-601L)
Descriptor: 145-mer DNA, CHLORIDE ION, Histone H2A, ...
Authors:Chua, E.Y.D, Vasudevan, D, Davey, G.E, Wu, B, Davey, C.A.
Deposit date:2011-11-25
Release date:2012-04-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The mechanics behind DNA sequence-dependent properties of the nucleosome
Nucleic Acids Res., 40, 2012
8VVB
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BU of 8vvb by Molmil
Influenza antibody L5A7 Fab
Descriptor: L5A7 Heavy Chain, L5A7 Light Chain
Authors:Harris, D.R, Olia, A.S, Kwong, P.D.
Deposit date:2024-01-30
Release date:2024-05-22
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody.
Front Immunol, 15, 2024
3SC2
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BU of 3sc2 by Molmil
REFINED ATOMIC MODEL OF WHEAT SERINE CARBOXYPEPTIDASE II AT 2.2-ANGSTROMS RESOLUTION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SERINE CARBOXYPEPTIDASE II (CPDW-II), alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Liao, D.-I, Remington, S.J.
Deposit date:1992-07-01
Release date:1993-10-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refined atomic model of wheat serine carboxypeptidase II at 2.2-A resolution.
Biochemistry, 31, 1992
1KBR
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BU of 1kbr by Molmil
CRYSTAL STRUCTURE OF UNLIGATED HPPK(R92A) FROM E.COLI AT 1.55 ANGSTROM RESOLUTION
Descriptor: 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION
Authors:Blaszczyk, J, Ji, X.
Deposit date:2001-11-06
Release date:2003-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
2PII
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BU of 2pii by Molmil
PII, GLNB PRODUCT
Descriptor: PII
Authors:Carr, P.D, Cheah, E, Suffolk, P.M, Ollis, D.L.
Deposit date:1995-05-02
Release date:1996-06-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of the signal transduction protein from Escherichia coli at 1.9 A.
Acta Crystallogr.,Sect.D, 52, 1996
2WT8
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BU of 2wt8 by Molmil
Structure of the N-terminal BRCT domain of human microcephalin (Mcph1)
Descriptor: ACETATE ION, CHLORIDE ION, MICROCEPHALIN
Authors:Richards, M.W, Roe, S.M, Bayliss, R.
Deposit date:2009-09-14
Release date:2009-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Pocket on the Surface of the N-Terminal Brct Domain of Mcph1 is Required to Prevent Abnormal Chromosome Condensation.
J.Mol.Biol., 395, 2010
3UTA
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BU of 3uta by Molmil
Crystal Structure of Nucleosome Core Particle Assembled with an Alpha-Satellite Sequence Containing Two TTAAA elements (NCP-TA2)
Descriptor: 145-mer DNA, CHLORIDE ION, Histone H2A, ...
Authors:Chua, E.Y.D, Vasudevan, D, Davey, G.E, Wu, B, Davey, C.A.
Deposit date:2011-11-25
Release date:2012-04-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:The mechanics behind DNA sequence-dependent properties of the nucleosome
Nucleic Acids Res., 40, 2012
1ZAE
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BU of 1zae by Molmil
Solution structure of the functional domain of phi29 replication organizer p16.7c
Descriptor: Early protein GP16.7
Authors:Asensio, J.L, Albert, A, Munoz-Espin, D, Gonzalez, C, Hermoso, J, Villar, L, Jimenez-Barbero, J, Salas, M, Meijer, W.J.J.
Deposit date:2005-04-06
Release date:2005-04-19
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the functional domain of phi29 replication organizer: insights into oligomerization and dna binding
J.Biol.Chem., 280, 2005
4BTM
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BU of 4btm by Molmil
TTBK1 in complex with inhibitor
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, SULFATE ION, ...
Authors:Xue, Y, Wan, P, Hillertz, P, Schweikart, F, Zhao, Y, Wissler, L, Dekker, N.
Deposit date:2013-06-18
Release date:2013-09-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:X-Ray Structural Analysis of Tau-Tubulin Kinase 1 and its Interactions with Small Molecular Inhibitors.
Chemmedchem, 8, 2013
1PZE
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BU of 1pze by Molmil
T.gondii LDH1 apo form
Descriptor: lactate dehydrogenase
Authors:Kavanagh, K.L, Elling, R.A, Wilson, D.K.
Deposit date:2003-07-10
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZG
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BU of 1pzg by Molmil
T.gondii LDH1 complexed with APAD and sulfate at 1.6 Angstroms
Descriptor: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, SULFATE ION, lactate dehydrogenase
Authors:Kavanagh, K.L, Elling, R.A, Wilson, D.K.
Deposit date:2003-07-10
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
4BVX
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BU of 4bvx by Molmil
Crystal structure of the AIMP3-MRS N-terminal domain complex with I3C
Descriptor: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1, METHIONINE--TRNA LIGASE, ...
Authors:Cho, H.Y, Seo, W.W, Cho, H.J, Kang, B.S.
Deposit date:2013-06-29
Release date:2014-07-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Assembly of Multi-tRNA Synthetase Complex Via Heterotetrameric Glutathione Transferase-Homology Domains.
J.Biol.Chem., 290, 2015
4LNU
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BU of 4lnu by Molmil
Nucleotide-free kinesin motor domain in complex with tubulin and a DARPin
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D1, GLYCEROL, ...
Authors:Cao, L, Gigant, B, Knossow, M.
Deposit date:2013-07-12
Release date:2014-12-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement
Nat Commun, 5, 2014
2PIJ
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BU of 2pij by Molmil
Structure of the Cro protein from prophage Pfl 6 in Pseudomonas fluorescens Pf-5
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BICARBONATE ION, Prophage Pfl 6 Cro, ...
Authors:Roessler, C.G, Roberts, S.A, Montfort, W.R, Cordes, M.H.J.
Deposit date:2007-04-13
Release date:2008-03-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Transitive homology-guided structural studies lead to discovery of Cro proteins with 40% sequence identity but different folds.
Proc.Natl.Acad.Sci.Usa, 105, 2008

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