4FJS
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![BU of 4fjs by Molmil](/molmil-images/mine/4fjs) | Crystal structure of ureidoglycolate dehydrogenase enzyme in apo form | Descriptor: | Ureidoglycolate dehydrogenase | Authors: | Kim, M.I, Shin, I, Lee, J, Rhee, S. | Deposit date: | 2012-06-12 | Release date: | 2013-01-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization. Plos One, 7, 2012
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1FUK
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5CXC
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![BU of 5cxc by Molmil](/molmil-images/mine/5cxc) | Structure of Ytm1 bound to the C-terminal domain of Erb1 in P 65 2 2 space group | Descriptor: | CHLORIDE ION, Ribosome biogenesis protein ERB1, Ribosome biogenesis protein YTM1 | Authors: | Wegrecki, M, Bravo, J. | Deposit date: | 2015-07-28 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
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5CYK
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![BU of 5cyk by Molmil](/molmil-images/mine/5cyk) | Structure of Ytm1 bound to the C-terminal domain of Erb1-R486E | Descriptor: | CHLORIDE ION, Ribosome biogenesis protein ERB1, Ribosome biogenesis protein YTM1 | Authors: | Wegrecki, M, Bravo, J. | Deposit date: | 2015-07-30 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
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4IJE
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![BU of 4ije by Molmil](/molmil-images/mine/4ije) | Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain R312A/K319A/R322A mutant | Descriptor: | PHOSPHATE ION, POTASSIUM ION, Polymerase cofactor VP35, ... | Authors: | Binning, J.B, Wang, T, Leung, D.W, Xu, W, Borek, D, Amarasinghe, G.K. | Deposit date: | 2012-12-21 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Development of RNA Aptamers Targeting Ebola Virus VP35. Biochemistry, 52, 2013
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412D
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![BU of 412d by Molmil](/molmil-images/mine/412d) | DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-METHYL-[TRI(OXYETHYL)] RIBONUCLEOSIDE | Descriptor: | DNA (5'-D(*GP*CP*GP*TP*AP*(126)P*AP*CP*GP*C)-3'), MAGNESIUM ION | Authors: | Tereshko, V, Portmann, S, Tay, E.C, Martin, P, Natt, F, Altmann, K.H, Egli, M. | Deposit date: | 1998-06-30 | Release date: | 1998-07-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues. Biochemistry, 37, 1998
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5CXB
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3ZFV
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![BU of 3zfv by Molmil](/molmil-images/mine/3zfv) | Crystal structure of an archaeal CRISPR-associated Cas6 nuclease | Descriptor: | CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS6 1, GLYCEROL | Authors: | Reeks, J, Liu, H, White, M.F, Naismith, J.H. | Deposit date: | 2012-12-12 | Release date: | 2013-04-03 | Last modified: | 2013-05-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of a Dimeric Crenarchaeal Cas6 Enzyme with an Atypical Active Site for Crispr RNA Processing Biochem.J., 452, 2013
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410D
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![BU of 410d by Molmil](/molmil-images/mine/410d) | DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-ETHOXYMETHYLENE RIBONUCLEOSIDE | Descriptor: | DNA (5'-D(*GP*CP*GP*TP*AP*(T38)P*AP*CP*GP*C)-3'), SPERMINE | Authors: | Tereshko, V, Portmann, S, Tay, E.C, Martin, P, Natt, F, Altmann, K.H, Egli, M. | Deposit date: | 1998-06-30 | Release date: | 1998-07-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues. Biochemistry, 37, 1998
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1AB3
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![BU of 1ab3 by Molmil](/molmil-images/mine/1ab3) | RIBOSOMAL PROTEIN S15 FROM THERMUS THERMOPHILUS, NMR, 26 STRUCTURES | Descriptor: | RIBOSOMAL RNA BINDING PROTEIN S15 | Authors: | Berglund, H, Rak, A, Serganov, A, Garber, M, Hard, T. | Deposit date: | 1997-02-03 | Release date: | 1997-04-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the ribosomal RNA binding protein S15 from Thermus thermophilus. Nat.Struct.Biol., 4, 1997
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411D
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![BU of 411d by Molmil](/molmil-images/mine/411d) | DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-METHOXYETHYL RIBONUCLEOSIDE | Descriptor: | DNA (5'-D(*GP*CP*GP*TP*AP*(T39)P*AP*CP*GP*C)-3') | Authors: | Tereshko, V, Portmann, S, Tay, E.C, Martin, P, Natt, F, Altmann, K.H, Egli, M. | Deposit date: | 1998-06-30 | Release date: | 1998-07-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues. Biochemistry, 37, 1998
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3HD4
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![BU of 3hd4 by Molmil](/molmil-images/mine/3hd4) | MHV Nucleocapsid Protein NTD | Descriptor: | Nucleoprotein | Authors: | Giedroc, D.P, Keane, S.C, Dann III, C.E. | Deposit date: | 2009-05-06 | Release date: | 2009-11-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.747 Å) | Cite: | Coronavirus N Protein N-Terminal Domain (NTD) Specifically Binds the Transcriptional Regulatory Sequence (TRS) and Melts TRS-cTRS RNA Duplexes. J.Mol.Biol., 394, 2009
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3DJX
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![BU of 3djx by Molmil](/molmil-images/mine/3djx) | Bovine Seminal Ribonuclease- cytidine 5' phosphate complex | Descriptor: | CYTIDINE-5'-MONOPHOSPHATE, Seminal ribonuclease | Authors: | Dossi, K, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | Deposit date: | 2008-06-24 | Release date: | 2009-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors Eur.J.Med.Chem., 44, 2009
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1BVI
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![BU of 1bvi by Molmil](/molmil-images/mine/1bvi) | RIBONUCLEASE T1 (WILDTYPE) COMPLEXED WITH 2'GMP | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | Authors: | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | Deposit date: | 1998-09-15 | Release date: | 1998-09-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Dissection of the structural and functional role of a conserved hydration site in RNase T1. Protein Sci., 8, 1999
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3DJQ
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![BU of 3djq by Molmil](/molmil-images/mine/3djq) | Bovine Seminal Ribonuclease- Uridine 5' diphosphate complex | Descriptor: | Seminal ribonuclease, URIDINE-5'-DIPHOSPHATE | Authors: | Dossi, K, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | Deposit date: | 2008-06-24 | Release date: | 2009-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors Eur.J.Med.Chem., 44, 2009
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3DJV
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![BU of 3djv by Molmil](/molmil-images/mine/3djv) | Bovine Seminal Ribonuclease- cytidine 3' phosphate complex | Descriptor: | CYTIDINE-3'-MONOPHOSPHATE, Seminal ribonuclease | Authors: | Dossi, K, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | Deposit date: | 2008-06-24 | Release date: | 2009-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors Eur.J.Med.Chem., 44, 2009
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3AIA
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![BU of 3aia by Molmil](/molmil-images/mine/3aia) | Crystal structure of DUF358 reveals a putative SPOUT-class methltransferase | Descriptor: | S-ADENOSYLMETHIONINE, UPF0217 protein MJ1640, pentane-2,2,4,4-tetrol | Authors: | Yuan, Y.A, Chen, H.Y. | Deposit date: | 2010-05-11 | Release date: | 2011-03-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of Mj1640/DUF358 protein reveals a putative SPOUT-class RNA methyltransferase J Mol Cell Biol, 2, 2010
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1WXX
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![BU of 1wxx by Molmil](/molmil-images/mine/1wxx) | Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8 | Descriptor: | PHOSPHATE ION, POTASSIUM ION, hypothetical protein TTHA1280 | Authors: | Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-02-02 | Release date: | 2005-08-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine. Acta Crystallogr.,Sect.F, 61, 2005
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9EUR
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![BU of 9eur by Molmil](/molmil-images/mine/9eur) | Mpro WT from SARS-CoV-2 with 298Q mutation | Descriptor: | Replicase polyprotein 1a | Authors: | Plewka, J, Lis, K, Czarna, A, Pyrc, K, Kantyka, T, Chykunova, Y. | Deposit date: | 2024-03-28 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.113 Å) | Cite: | SARS-CoV-2 M pro oligomerization as a potential target for therapy. Int.J.Biol.Macromol., 267, 2024
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9EPL
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![BU of 9epl by Molmil](/molmil-images/mine/9epl) | Mpro from SARS-CoV-2 with 298Q mutation | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Non-structural protein 11, ... | Authors: | Plewka, J, Lis, K, Czarna, A, Pyrc, K, Kantyka, T, Chykunova, Y. | Deposit date: | 2024-03-18 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | SARS-CoV-2 M pro oligomerization as a potential target for therapy. Int.J.Biol.Macromol., 267, 2024
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9EWM
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![BU of 9ewm by Molmil](/molmil-images/mine/9ewm) | Mpro from SARS-CoV-2 with R4Q R298Q double mutations | Descriptor: | Non-structural protein 11 | Authors: | Plewka, J, Lis, K, Chykunova, Y, Czarna, A, Kantyka, T, Pyrc, K. | Deposit date: | 2024-04-04 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | SARS-CoV-2 M pro oligomerization as a potential target for therapy. Int.J.Biol.Macromol., 267, 2024
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9EWO
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![BU of 9ewo by Molmil](/molmil-images/mine/9ewo) | Mpro from SARS-CoV-2 with R4A R298A double mutations | Descriptor: | Non-structural protein 11, SULFATE ION | Authors: | Plewka, J, Lis, K, Chykunova, Y, Czarna, A, Kantyka, T, Pyrc, K. | Deposit date: | 2024-04-04 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | SARS-CoV-2 M pro oligomerization as a potential target for therapy. Int.J.Biol.Macromol., 267, 2024
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9EWN
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![BU of 9ewn by Molmil](/molmil-images/mine/9ewn) | Mpro from SARS-CoV-2 with 4Q mutation | Descriptor: | Non-structural protein 11 | Authors: | Plewka, J, Lis, K, Czarna, A, Kantyka, T, Pyrc, K. | Deposit date: | 2024-04-04 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.113 Å) | Cite: | SARS-CoV-2 M pro oligomerization as a potential target for therapy. Int.J.Biol.Macromol., 267, 2024
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9EUS
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![BU of 9eus by Molmil](/molmil-images/mine/9eus) | Mpro from SARS-CoV-2 with R298A mutation | Descriptor: | GLYCEROL, Replicase polyprotein 1a | Authors: | Plewka, J, Lis, K, Czarna, A, Pyrc, K, Kantyka, T, Chykunova, Y. | Deposit date: | 2024-03-28 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | SARS-CoV-2 M pro oligomerization as a potential target for therapy. Int.J.Biol.Macromol., 267, 2024
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9EPM
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![BU of 9epm by Molmil](/molmil-images/mine/9epm) | Mpro from SARS-CoV-2 with 4A mutation | Descriptor: | Non-structural protein 11 | Authors: | Plewka, J, Lis, K, Czarna, A, Pyrc, K, Kantyka, T, Chykunova, Y. | Deposit date: | 2024-03-19 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.981 Å) | Cite: | SARS-CoV-2 M pro oligomerization as a potential target for therapy. Int.J.Biol.Macromol., 267, 2024
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